iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-117322

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01026579

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000007936.1	ENSTGUT00000008298.1	ENSTGUP00000008213.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	8.30e-108	360.4	734	1561

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtC+mNS +Qc sn+++l++++ + ++  +ln++np ++kg+++k++ +l++elw++++k+++p +l  +++k+a++f+g
   Q: 734  TGLSNLGNTCFMNSSIQCVSNTQPLTRYFISgRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKNIAPLKLRWTIAKYAPRFNG 820
           7******************************9******************************************************* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           ++qqD+qE+laflld+l+e+l++ ++kp+ e++++d   ++d+     a+e++ ++n+s+++dlF+gqlksq+kc++c+++s+r++p
   Q: 821  FQQQDSQELLAFLLDGLHEDLNRVHDKPYVELKDSD--GRPDWevaaeAWENHLRRNRSIVVDLFHGQLKSQVKCKTCGHISVRFDP 905
           ********************************9999..6666666777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           f+ lslp+p+++ +++e                                                                      
   Q: 906  FNFLSLPLPMDSYMHLEitvikldgttpvryglrlnmdekytglkkqlselcglkpeqillaevhssniknfpqdnqkvrlsvsgfl 992
           *************9999********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 993  cafeipipgsptsasspvqtetstgpsangapsilmngdvakpslipngmpntvvpcgtersppswtlnghvpslcdspctgyiiav 1079
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1080 hrkmmrtelyflssqknrpslfgmplivpctvhtrkrdlydavwiqvsrlasplppqeasnhaqdcddsmgyqypftlrvvqkdgns 1166
           *************************************************************************************** PP
   S: 186  ...................................................................slqdcLesftkeeelegenk 205
                                                                              +l++cL++ft+eeel ++++
   Q: 1167 cawcpwyrfcrgckiectedracvgsayiavdwdptalhlryqtsqeriveehesveqsrraqaepiNLDSCLRAFTSEEELGEDEM 1253
           *************************************************************************************** PP
   S: 206  yycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts........................ 267
           yyc+kck ++ a+kkl+l++lP++Li+hLkRf+f +   + +k +k v+fp+e +d s f+++                        
   Q: 1254 YYCSKCKTHCLATKKLDLWRLPPILIIHLKRFQFVNG--RWIKSQKIVKFPREnFDPSAFLVQrdpshfqrkqltlqveslpearpg 1338
           ********************************99775..5569********************899888888888888888888888 PP
   S: 268  ...............................................................................peekqke. 274
                                                                                          +     + 
   Q: 1339 qgdtrkadvqntgtagegdtlnrspsslnttvlnnvkaspslgrksgtscpssknsspnssprtlgrgkgrlrlpqlgkN-----Kl 1420
           88888888888888888888887777777777777777777777777777666666666666666666666665555550.....05 PP
   S: 275  ................................................................................kkkYeLi 281
                                                                                           + +Y+L+
   Q: 1421 ssskenlaanrengaeheqgdaltkgqalggsqselypgqdsegalangflweqsslsngqgenhseddtaddqrddgwlSPIYNLY 1507
           5555555566666666666666777777777777777777777777777777777777788888888899999999*********** PP
   S: 282  avvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
           a+ +HsG +++GHYv+y+kn ++kW++++Ds+++e++ +e+ +   ++aY+lfY+++
   Q: 1508 AISCHSGIMGGGHYVTYAKNPNNKWYCYNDSSCKELHPDEIDT---DSAYILFYEQQ 1561
           *******************************************...********985 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MGAKESRIGF LGYDEALRRV TDIELKRLKD AFKRTCGLSY YMTQQCFIRE VLGDGVPPKV 60
AEVIYCSFGG ISKGLHFNNL IVGLVLLTRG REEEKTKYIF SLFSNESGSY VVREEMEKML 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCGCCA AGGAGTCCCG CATCGGCTTC CTCGGCTACG ACGAGGCCCT GCGGAGGGGT 60
GAGGCGGCGG GGGAGGGTTG GGTGGAGGTC GGCGGGGAGG GGTGTGGGGG CCCCGCGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF13202--EF-hand_5
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP
SM00054--EFh

Gene Ontology

GO:0005509--F:calcium ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001611	Ailuropoda melanoleuca	85.23	0.00e+00	2298.00
IUUC-Apl-003272	Anas platyrhynchos	91.49	0.00e+00	2844.00
IUUC-Aca-005057	Anolis carolinensis	84.76	0.00e+00	2308.00
IUUC-Ame-010781	Astyanax mexicanus	75.05	0.00e+00	2390.00
IUUC-Bta-013502	Bos taurus	81.89	0.00e+00	2484.00
IUUC-Cja-018754	Callithrix jacchus	85.63	0.00e+00	2733.00
IUUC-Cfa-020526	Canis familiaris	85.82	0.00e+00	2705.00
IUUC-Cpo-021568	Cavia porcellus	81.02	0.00e+00	2426.00
IUUC-Csa-023143	Chlorocebus sabaeus	85.13	0.00e+00	2684.00
IUUC-Cho-024603	Choloepus hoffmanni	55.29	5.00e-174	605.00
IUUC-Cin-025583	Ciona intestinalis	54.49	0.00e+00	880.00
IUUC-Csv-026344	Ciona savignyi	46.56	0.00e+00	1180.00
IUUC-Dre-028121	Danio rerio	76.78	0.00e+00	2378.00
IUUC-Dno-029911	Dasypus novemcinctus	84.60	0.00e+00	2638.00
IUUC-Dor-030608	Dipodomys ordii	63.27	0.00e+00	647.00
IUUC-Dme-032094	Drosophila melanogaster	44.05	3.00e-122	433.00
IUUC-Ete-032639	Echinops telfairi	81.39	0.00e+00	1353.00
IUUC-Eca-034253	Equus caballus	85.39	0.00e+00	2638.00
IUUC-Eeu-035084	Erinaceus europaeus	74.35	0.00e+00	1461.00
IUUC-Fca-035474	Felis catus	83.60	0.00e+00	2149.00
IUUC-Fal-036985	Ficedula albicollis	97.20	0.00e+00	3019.00
IUUC-Gmo-039568	Gadus morhua	81.45	0.00e+00	2128.00
IUUC-Gga-040509	Gallus gallus	90.51	0.00e+00	2893.00
IUUC-Gac-041757	Gasterosteus aculeatus	80.11	0.00e+00	2169.00
IUUC-Ggo-044956	Gorilla gorilla	81.33	0.00e+00	1698.00
IUUC-Hsa-046107	Homo sapiens	85.44	0.00e+00	2707.00
IUUC-Itr-048865	Ictidomys tridecemlineatus	78.95	0.00e+00	967.00
IUUC-Lch-050681	Latimeria chalumnae	78.14	0.00e+00	2373.00
IUUC-Loc-052474	Lepisosteus oculatus	78.33	0.00e+00	2494.00
IUUC-Laf-054273	Loxodonta africana	85.63	0.00e+00	2710.00
IUUC-Mcc-054718	Macaca mulatta	85.31	0.00e+00	2707.00
IUUC-Meu-056558	Macropus eugenii	70.09	0.00e+00	1345.00
IUUC-Mga-059892	Meleagris gallopavo	92.40	0.00e+00	2833.00
IUUC-Mmr-060866	Microcebus murinus	85.48	0.00e+00	2744.00
IUUC-Mdo-062607	Monodelphis domestica	86.36	0.00e+00	2775.00
IUUC-Mmu-063797	Mus musculus	85.69	0.00e+00	2759.00
IUUC-Mpu-066121	Mustela putorius furo	85.76	0.00e+00	2758.00
IUUC-Mlu-067581	Myotis lucifugus	84.95	0.00e+00	2709.00
IUUC-Nle-069916	Nomascus leucogenys	83.26	0.00e+00	2582.00
IUUC-Opr-071073	Ochotona princeps	77.20	0.00e+00	1095.00
IUUC-Ont-071310	Oreochromis niloticus	81.86	0.00e+00	2169.00
IUUC-Oan-073356	Ornithorhynchus anatinus	85.31	0.00e+00	2719.00
IUUC-Ocu-074216	Oryctolagus cuniculus	86.05	0.00e+00	2732.00
IUUC-Ola-087434	Oryzias latipes	75.12	0.00e+00	2271.00
IUUC-Oga-089034	Otolemur garnettii	85.67	0.00e+00	2611.00
IUUC-Oar-090369	Ovis aries	85.58	0.00e+00	2705.00
IUUC-Ptr-090605	Pan troglodytes	85.56	0.00e+00	2713.00
IUUC-Pan-092381	Papio anubis	85.02	0.00e+00	2621.00
IUUC-Psi-093819	Pelodiscus sinensis	88.78	0.00e+00	2789.00
IUUC-Pma-094480	Petromyzon marinus	63.98	0.00e+00	1467.00
IUUC-Pfo-096561	Poecilia formosa	74.55	0.00e+00	2300.00
IUUC-Pab-097643	Pongo abelii	82.89	0.00e+00	2595.00
IUUC-Pca-100944	Procavia capensis	69.36	0.00e+00	920.00
IUUC-Pva-102732	Pteropus vampyrus	76.15	0.00e+00	2363.00
IUUC-Rno-105113	Rattus norvegicus	85.33	0.00e+00	2707.00
IUUC-Sha-107608	Sarcophilus harrisii	75.90	3.00e-156	544.00
IUUC-Sar-113201	Sorex araneus	75.21	0.00e+00	1504.00
IUUC-Ssc-115469	Sus scrofa	75.45	2.00e-147	514.00
IUUC-Tru-118705	Takifugu rubripes	69.35	0.00e+00	680.00
IUUC-Tsy-119433	Tarsius syrichta	73.93	0.00e+00	1919.00
IUUC-Tni-120631	Tetraodon nigroviridis	80.14	0.00e+00	2083.00
IUUC-Tbe-127553	Tupaia belangeri	82.70	0.00e+00	650.00
IUUC-Ttr-128260	Tursiops truncatus	84.57	0.00e+00	2701.00
IUUC-Vpa-130479	Vicugna pacos	80.79	0.00e+00	2504.00
IUUC-Xtr-132686	Xenopus tropicalis	82.79	0.00e+00	2595.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence