iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000012559.1	ENSONIT00000015825.1	ENSONIP00000015810.1
ENSONIG00000012559.1	ENSONIT00000015826.1	ENSONIP00000015811.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.20e-15	56.9	40	81

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktc 43
           v ++ +C +sl++ rdPvv+p+G+ y++++I +++ +++++ 
   Q: 40   VKDFDCCCLSLQPCRDPVVTPDGYLYEKQAILEYILHQKTQI 81
           567789*****************************9998833 PP

Organism

Oreochromis niloticus

Functional Description
(View)

Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity.

Protein Sequence
(Fasta)

MTRHGKNCTA GAVYTYHEKK KDTAASGYGT QSVRLGRDAV KDFDCCCLSL QPCRDPVVTP 60
DGYLYEKQAI LEYILHQKTQ IAKKMKAYEK QKQAQRSSNQ LESKSEERER VERFKTKENS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTCACTCAC CAGTGTTCGA GTAACGTGGA GAAGAAGAAG AACAAAACGA AATACAACGA 60
CGAAGAAGAG CGTGTGGCTG TAGTCTGCGT TAAGAAAAGA TTGTTCCGGA ATATAATTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome

Interpro

IPR016818--Nitric_oxide_synth-interacting
IPR031790--Znf-NOSIP
IPR013083--Znf_RING/FYVE/PHD

Pfam

PF15906--zf-NOSIP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0050999--P:regulation of nitric-oxide synthase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000769	Aegilops tauschii	45.35	7.00e-16	79.00
IUUC-Aml-002069	Ailuropoda melanoleuca	64.54	1.00e-114	405.00
IUUC-Atr-002661	Amborella trichopoda	28.43	2.00e-27	116.00
IUUC-Aca-004630	Anolis carolinensis	66.56	2.00e-117	415.00
IUUC-Aly-006316	Arabidopsis lyrata	28.62	2.00e-30	126.00
IUUC-Ath-007000	Arabidopsis thaliana	28.62	2.00e-30	125.00
IUUC-Acl-008175	Aspergillus clavatus	33.33	6.00e-07	48.50
IUUC-Afl-008440	Aspergillus flavus	25.40	4.00e-10	58.90
IUUC-Afu-009012	Aspergillus fumigatus	30.65	4.00e-07	49.30
IUUC-Ani-009153	Aspergillus nidulans	30.08	5.00e-04	38.90
IUUC-Ang-009556	Aspergillus niger	24.36	2.00e-11	63.50
IUUC-Aor-009892	Aspergillus oryzae	23.79	1.00e-08	54.30
IUUC-Ame-011874	Astyanax mexicanus	79.74	2.00e-127	448.00
IUUC-Bgr-012090	Blumeria graminis	25.35	6.00e-06	45.10
IUUC-Bta-012956	Bos taurus	66.67	5.00e-119	420.00
IUUC-Bci-013897	Botrytis cinerea	37.50	2.00e-08	53.50
IUUC-Bdi-014968	Brachypodium distachyon	29.29	7.00e-34	137.00
IUUC-Bol-015578	Brassica oleracea	29.64	6.00e-32	131.00
IUUC-Bra-017234	Brassica rapa	29.64	6.00e-32	131.00
IUUC-Cel-018637	Caenorhabditis elegans	45.25	2.00e-57	215.00
IUUC-Cja-019632	Callithrix jacchus	66.23	3.00e-120	424.00
IUUC-Cfa-020192	Canis familiaris	66.56	8.00e-119	420.00
IUUC-Cpo-021939	Cavia porcellus	66.23	7.00e-119	420.00
IUUC-Cre-023005	Chlamydomonas reinhardtii	32.24	8.00e-37	147.00
IUUC-Csa-023802	Chlorocebus sabaeus	65.89	8.00e-120	423.00
IUUC-Cho-024637	Choloepus hoffmanni	52.20	1.00e-42	166.00
IUUC-Cin-025180	Ciona intestinalis	52.94	5.00e-88	317.00
IUUC-Csv-026206	Ciona savignyi	58.04	1.00e-45	175.00
IUUC-Cgl-026696	Colletotrichum gloeosporioides	23.55	6.00e-12	65.10
IUUC-Cne-026827	Cryptococcus neoformans	25.65	2.00e-08	53.50
IUUC-Dre-028092	Danio rerio	80.46	2.00e-135	474.00
IUUC-Dno-029501	Dasypus novemcinctus	61.31	1.00e-102	367.00
IUUC-Dor-030542	Dipodomys ordii	65.89	7.00e-120	423.00
IUUC-Dse-031188	Dothistroma septosporum	24.31	1.00e-14	73.90
IUUC-Dme-031734	Drosophila melanogaster	47.54	2.00e-81	295.00
IUUC-Eca-033577	Equus caballus	66.89	1.00e-120	425.00
IUUC-Fca-035761	Felis catus	66.56	2.00e-118	418.00
IUUC-Fox-037703	Fusarium oxysporum	25.36	4.00e-13	68.90
IUUC-Fso-038208	Fusarium solani	24.79	1.00e-13	70.50
IUUC-Gmo-038523	Gadus morhua	71.35	3.00e-73	267.00
IUUC-Ggr-040087	Gaeumannomyces graminis	29.50	1.00e-08	53.90
IUUC-Gac-042621	Gasterosteus aculeatus	77.12	2.00e-128	451.00
IUUC-Gma-042698	Glycine max	29.10	5.00e-31	128.00
IUUC-Ggo-045357	Gorilla gorilla	66.23	2.00e-120	425.00
IUUC-Hsa-046195	Homo sapiens	66.23	2.00e-120	425.00
IUUC-Hvu-047174	Hordeum vulgare	29.29	2.00e-33	135.00
IUUC-Itr-048487	Ictidomys tridecemlineatus	66.56	6.00e-118	417.00
IUUC-Lch-050569	Latimeria chalumnae	66.13	1.00e-108	385.00
IUUC-Lpe-050992	Leersia perrieri	32.35	4.00e-22	99.40
IUUC-Loc-052522	Lepisosteus oculatus	74.83	2.00e-120	425.00
IUUC-Lma-053254	Leptosphaeria maculans	24.16	6.00e-08	52.00
IUUC-Laf-053397	Loxodonta africana	65.56	7.00e-118	416.00
IUUC-Mcc-054681	Macaca mulatta	66.56	1.00e-120	426.00
IUUC-Meu-056723	Macropus eugenii	65.56	2.00e-118	418.00
IUUC-Mor-056961	Magnaporthe oryzae	29.46	6.00e-09	55.10
IUUC-Mpo-057359	Magnaporthe poae	21.31	8.00e-06	44.30
IUUC-Mtr-058063	Medicago truncatula	29.43	9.00e-34	137.00
IUUC-Mla-059004	Melampsora laricipopulina	28.97	1.00e-21	97.10
IUUC-Mvi-060460	Microbotryum violaceum	30.51	1.00e-25	110.00
IUUC-Mmr-060847	Microcebus murinus	66.56	5.00e-121	427.00
IUUC-Mdo-062480	Monodelphis domestica	65.46	1.00e-118	419.00
IUUC-Mmu-063809	Mus musculus	65.23	1.00e-117	416.00
IUUC-Mac-064870	Musa acuminata	29.77	1.00e-34	140.00
IUUC-Mpu-066322	Mustela putorius furo	65.03	5.00e-119	421.00
IUUC-Mlu-067556	Myotis lucifugus	66.23	7.00e-119	420.00
IUUC-Nfi-068440	Neosartorya fischeri	24.23	3.00e-09	56.20
IUUC-Ncr-068898	Neurospora crassa	33.33	4.00e-06	45.80
IUUC-Nle-070049	Nomascus leucogenys	66.23	3.00e-120	424.00
IUUC-Opr-070972	Ochotona princeps	65.23	4.00e-119	421.00
IUUC-Oan-073296	Ornithorhynchus anatinus	94.92	1.00e-30	125.00
IUUC-Ocu-074218	Oryctolagus cuniculus	66.43	5.00e-105	374.00
IUUC-Oba-075284	Oryza barthii	28.96	9.00e-32	130.00
IUUC-Obr-076651	Oryza brachyantha	28.76	2.00e-34	139.00
IUUC-Ogl-077899	Oryza glaberrima	28.96	9.00e-32	130.00
IUUC-Ogu-078477	Oryza glumaepatula	29.29	4.00e-32	132.00
IUUC-Oin-080011	Oryza indica	28.96	8.00e-32	130.00
IUUC-Olo-080545	Oryza longistaminata	28.96	4.00e-25	109.00
IUUC-Ome-081543	Oryza meridionalis	28.96	8.00e-32	130.00
IUUC-Oni-082955	Oryza nivara	28.96	8.00e-32	130.00
IUUC-Opu-083565	Oryza punctata	28.96	5.00e-32	131.00
IUUC-Oru-084474	Oryza rufipogon	28.96	8.00e-32	130.00
IUUC-Osa-085913	Oryza sativa	28.96	8.00e-32	130.00
IUUC-Ola-086851	Oryzias latipes	80.79	7.00e-144	503.00
IUUC-Olu-087724	Ostreococcus lucimarinus	29.13	3.00e-10	59.30
IUUC-Oga-087970	Otolemur garnettii	67.00	6.00e-120	423.00
IUUC-Oar-089756	Ovis aries	65.02	2.00e-112	398.00
IUUC-Ptr-091485	Pan troglodytes	65.23	5.00e-117	413.00
IUUC-Pan-091832	Papio anubis	66.23	2.00e-120	425.00
IUUC-Pma-094551	Petromyzon marinus	61.44	5.00e-104	370.00
IUUC-Ppa-095255	Physcomitrella patens	28.67	3.00e-29	122.00
IUUC-Pfo-096373	Poecilia formosa	84.21	7.00e-144	503.00
IUUC-Pab-098247	Pongo abelii	66.23	3.00e-120	424.00
IUUC-Pop-099186	Populus trichocarpa	30.30	6.00e-34	137.00
IUUC-Pca-100677	Procavia capensis	60.14	1.00e-91	329.00
IUUC-Ppe-101403	Prunus persica	29.10	7.00e-32	130.00
IUUC-Pva-103000	Pteropus vampyrus	66.89	9.00e-121	426.00
IUUC-Pgr-103663	Puccinia graminis	29.10	1.00e-27	117.00
IUUC-Ptt-103712	Puccinia triticina	35.38	2.00e-07	49.30
IUUC-Pte-104287	Pyrenophora teres	22.18	4.00e-13	68.90
IUUC-Pyt-104579	Pyrenophora triticirepentis	31.25	4.00e-07	48.90
IUUC-Rno-106069	Rattus norvegicus	65.89	5.00e-119	420.00
IUUC-Sha-106553	Sarcophilus harrisii	65.23	1.00e-116	412.00
IUUC-Smo-108874	Selaginella moellendorffii	32.00	3.00e-38	152.00
IUUC-Sit-110307	Setaria italica	29.29	2.00e-30	126.00
IUUC-Sly-111094	Solanum lycopersicum	29.43	1.00e-33	136.00
IUUC-Stu-112363	Solanum tuberosum	29.43	1.00e-33	137.00
IUUC-Sar-113480	Sorex araneus	65.56	4.00e-114	404.00
IUUC-Sbi-113939	Sorghum bicolor	29.97	3.00e-33	135.00
IUUC-Ssc-115644	Sus scrofa	65.89	9.00e-120	422.00
IUUC-Tru-118781	Takifugu rubripes	78.36	3.00e-140	490.00
IUUC-Tni-119672	Tetraodon nigroviridis	76.74	3.00e-36	142.00
IUUC-Tca-121795	Theobroma cacao	29.10	6.00e-35	140.00
IUUC-Tre-122037	Trichoderma reesei	32.47	3.00e-07	49.70
IUUC-Tvi-122524	Trichoderma virens	26.64	6.00e-14	71.60
IUUC-Tae-122828	Triticum aestivum	29.63	1.00e-33	136.00
IUUC-Tur-126387	Triticum urartu	29.34	5.00e-27	115.00
IUUC-Tme-127111	Tuber melanosporum	36.90	3.00e-08	53.10
IUUC-Ttr-128227	Tursiops truncatus	65.69	9.00e-119	419.00
IUUC-Vda-129924	Verticillium dahliae	25.00	1.00e-15	77.40
IUUC-Vpa-130802	Vicugna pacos	67.82	8.00e-32	130.00
IUUC-Vvi-131105	Vitis vinifera	30.64	3.00e-34	139.00
IUUC-Xtr-132830	Xenopus tropicalis	64.69	1.00e-116	412.00
IUUC-Xma-133618	Xiphophorus maculatus	83.44	8.00e-138	483.00
IUUC-Zma-135389	Zea mays	29.29	3.00e-31	129.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence