iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
ULD/UDP/UFD/UBX	UBX	11243799

Classification

Family	E-value	Score	Start	End
ULD/UDP/UFD/UBX	1.30e-18	67.3	616	693
ULD/UDP/UBQ/UBQ_Other	1.10e-08	34.8	152	181

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfveyllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllve 80
           +t+++++++R p G +l+r+F  +++l+++ +fv+ ++++  ++++L+s++Prr+l+  e+++tl++++L+p++++++e
   Q: 616  ETGTSKIRVRKPTGDFLERRFFINNNLQDLLNFVT-ANGFLIEEYKLISSWPRRDLTAIESSQTLESLKLYPQETVILE 693
           5779*******************************.****************************************986 PP

ULD/UDP/UBQ/UBQ_Other

   S: 13   ltlkvnpsdtVaeLKekiekklgippeqqr 42
           ++l++++ +tV +LK+ki+ ++++p+ +q+
   Q: 152  YQLRLPSEATVEQLKRKIFAETSVPVCRQA 181
           788877788****************88875 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MSENKDEALT SFQSITGIDD VGEAFSHLEA ADWNLVEALS RVIPHEDAPL TSPHPILVPE 60
PPARNAVEST NGFRPPGFDE MPGTSNASGF FAAALQNQNQ NLNLNQPHIQ QRFPTSQLLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCCAATGAG CATAGGTTAA AAAATTTAAA AAAAAAAATA CATGAATATA TAAAAAGGTT 60
TGAAGAAATT TATTTCAAAG TGCCGTTAGC AGCAGTAGCG CTACTGCGCA TAAATCGCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR033043--FAF1_UBX
IPR012336--Thioredoxin-like_fold
IPR006577--UAS
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50033--UBX

Pfam

PF00789--UBX

SMART

SM00594--UAS
SM00166--UBX

Gene Ontology

GO:0005737--C:cytoplasm
GO:0008219--P:cell death
GO:0002814--P:negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria
GO:0061060--P:negative regulation of peptidoglycan recognition protein signaling pathway
GO:0045861--P:negative regulation of proteolysis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002153	Ailuropoda melanoleuca	36.20	8.00e-93	333.00
IUUC-Apl-004127	Anas platyrhynchos	36.80	4.00e-95	341.00
IUUC-Aca-005188	Anolis carolinensis	33.91	2.00e-98	352.00
IUUC-Ame-010696	Astyanax mexicanus	35.12	1.00e-74	273.00
IUUC-Bta-012965	Bos taurus	33.10	2.00e-97	348.00
IUUC-Cel-018420	Caenorhabditis elegans	24.13	3.00e-14	72.40
IUUC-Cja-019128	Callithrix jacchus	36.38	7.00e-93	333.00
IUUC-Cfa-021201	Canis familiaris	39.91	2.00e-81	296.00
IUUC-Cpo-021475	Cavia porcellus	34.88	3.00e-67	248.00
IUUC-Csa-024076	Chlorocebus sabaeus	36.38	5.00e-93	334.00
IUUC-Cho-025067	Choloepus hoffmanni	30.07	1.00e-80	293.00
IUUC-Cin-025663	Ciona intestinalis	34.29	1.00e-46	179.00
IUUC-Csv-025894	Ciona savignyi	31.67	7.00e-32	130.00
IUUC-Dre-027508	Danio rerio	35.59	2.00e-84	306.00
IUUC-Dno-029336	Dasypus novemcinctus	35.85	6.00e-92	330.00
IUUC-Dor-030218	Dipodomys ordii	34.45	1.00e-85	309.00
IUUC-Ete-032860	Echinops telfairi	28.76	7.00e-23	101.00
IUUC-Eca-034321	Equus caballus	36.03	5.00e-89	320.00
IUUC-Eeu-034844	Erinaceus europaeus	41.56	8.00e-24	104.00
IUUC-Fca-036575	Felis catus	38.76	1.00e-67	249.00
IUUC-Fal-037128	Ficedula albicollis	33.38	3.00e-99	355.00
IUUC-Fox-037839	Fusarium oxysporum	31.25	4.80e-02	31.20
IUUC-Fso-038401	Fusarium solani	35.71	2.60e-02	32.00
IUUC-Gmo-038694	Gadus morhua	37.46	7.00e-92	330.00
IUUC-Gga-040826	Gallus gallus	36.40	1.00e-94	340.00
IUUC-Gac-042125	Gasterosteus aculeatus	34.90	1.00e-101	362.00
IUUC-Ggo-045254	Gorilla gorilla	33.29	2.00e-99	355.00
IUUC-Hsa-046722	Homo sapiens	33.29	3.00e-99	355.00
IUUC-Hvu-047478	Hordeum vulgare	29.55	4.00e-06	45.40
IUUC-Itr-048149	Ictidomys tridecemlineatus	38.20	3.00e-28	117.00
IUUC-Lch-050312	Latimeria chalumnae	32.52	3.00e-45	174.00
IUUC-Loc-051990	Lepisosteus oculatus	36.48	8.00e-82	297.00
IUUC-Laf-054375	Loxodonta africana	38.92	5.00e-68	250.00
IUUC-Mcc-054627	Macaca mulatta	33.38	3.00e-97	348.00
IUUC-Meu-056611	Macropus eugenii	40.99	1.00e-37	150.00
IUUC-Mga-059400	Meleagris gallopavo	36.40	3.00e-95	341.00
IUUC-Mmr-060882	Microcebus murinus	35.52	7.00e-92	330.00
IUUC-Mdo-061874	Monodelphis domestica	36.44	8.00e-93	333.00
IUUC-Mmu-063444	Mus musculus	32.39	1.00e-93	336.00
IUUC-Mpu-065713	Mustela putorius furo	35.85	4.00e-92	331.00
IUUC-Mlu-068122	Myotis lucifugus	33.86	4.00e-97	348.00
IUUC-Nle-069025	Nomascus leucogenys	33.57	3.00e-99	355.00
IUUC-Opr-071089	Ochotona princeps	31.00	8.00e-86	310.00
IUUC-Ont-072421	Oreochromis niloticus	37.28	8.00e-92	330.00
IUUC-Oan-073092	Ornithorhynchus anatinus	35.94	2.00e-68	252.00
IUUC-Ogu-078652	Oryza glumaepatula	38.89	9.00e-10	58.20
IUUC-Olo-080220	Oryza longistaminata	38.89	2.00e-09	57.40
IUUC-Oni-082968	Oryza nivara	38.89	8.00e-10	57.80
IUUC-Ola-086497	Oryzias latipes	37.23	3.00e-93	335.00
IUUC-Oga-088854	Otolemur garnettii	36.16	7.00e-94	337.00
IUUC-Oar-090120	Ovis aries	32.96	7.00e-97	347.00
IUUC-Ptr-091554	Pan troglodytes	33.29	2.00e-99	355.00
IUUC-Pan-091985	Papio anubis	33.10	1.00e-97	350.00
IUUC-Psi-093548	Pelodiscus sinensis	36.06	6.00e-90	324.00
IUUC-Pma-094190	Petromyzon marinus	45.45	7.00e-19	85.10
IUUC-Pfo-096729	Poecilia formosa	37.32	5.00e-91	328.00
IUUC-Pab-097810	Pongo abelii	33.52	4.00e-99	355.00
IUUC-Pca-101079	Procavia capensis	34.31	1.00e-78	286.00
IUUC-Pva-102534	Pteropus vampyrus	29.42	1.00e-64	239.00
IUUC-Rno-105127	Rattus norvegicus	35.21	5.00e-87	314.00
IUUC-Sha-106667	Sarcophilus harrisii	36.22	1.00e-94	339.00
IUUC-Sar-113424	Sorex araneus	35.67	6.00e-66	244.00
IUUC-Ssc-115974	Sus scrofa	35.85	7.00e-92	330.00
IUUC-Tgu-116495	Taeniopygia guttata	33.38	1.00e-99	356.00
IUUC-Tru-118727	Takifugu rubripes	36.93	3.00e-90	325.00
IUUC-Tsy-118906	Tarsius syrichta	34.69	4.00e-86	311.00
IUUC-Tni-119717	Tetraodon nigroviridis	36.28	9.00e-89	320.00
IUUC-Tur-126134	Triticum urartu	34.15	5.00e-07	48.90
IUUC-Tbe-127849	Tupaia belangeri	30.48	3.00e-19	89.40
IUUC-Ttr-128660	Tursiops truncatus	33.98	2.00e-80	292.00
IUUC-Vpa-130359	Vicugna pacos	32.81	2.00e-95	342.00
IUUC-Xtr-132212	Xenopus tropicalis	42.13	1.00e-81	295.00
IUUC-Xma-132989	Xiphophorus maculatus	36.41	3.00e-90	325.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence