iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059400

Ensembl Protein ID

ENSMGAP00000011439.1

UniProt Accession

G1NEQ8; G1NEQ8_MELGA

Protein Name

Uncharacterized protein

Gene Name

FAF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000010948.1	ENSMGAT00000012315.1	ENSMGAP00000011439.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.30e-06	28.1	8	45
ULD/UDP/UFD/UBX	1.70e-19	69.9	570	647
ULD/UDP/UBQ/UBQ_Other	8.60e-09	34.9	204	236

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 4    edkleqlve.MGF.dreealqaLraannnleaAveyLl 39
           ++++ +l++ +G+ + +ea++ L+++n++l aA++ ++
   Q: 8    NQLISELKAcTGIeNIDEAITLLEQNNWDLVAAINGVI 45
           89********************************9875 PP

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfveyllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllve 80
           t++ ++l+iR+p+G++++r+F +s +l+ +++fv+ ++++++++++L+ +fPrr++++ + +++l e +L+p+++l++e
   Q: 570  TESVSKLRIRTPSGEFFERRFLASSKLQVVFDFVA-SKGYPWEEYKLLGTFPRRDVTQLDPNKSLLEVKLYPQETLFLE 647
           4559*******************************.****************************************986 PP

ULD/UDP/UBQ/UBQ_Other

   S: 11   s.eltlkvnpsdtVaeLKekiekklgip.peqq 41
             e+ l+++ s+t++e+K+ ++++++ip ++qq
   Q: 204  QrEYNLNFSGSSTIQEVKRNVYDLTSIPvRHQQ 236
           44788889********************77776 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MKINLNKNQL ISELKACTGI ENIDEAITLL EQNNWDLVAA INGVIPQENG ILQSEYGGET 60
LQGPAYGPTS HSTAASSASS SSSAFRHVVP SRQIVERQPR MLDFRVEYRD RNVDVVLEDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAAATAA ATCTGAATAA AAATCAGTTA ATCTCCGAAT TAAAGGGGAA AAAATTCTCA 60
TTGTATTTCT AACTTATTGT TAACTTAATA ACAAAGGTAT GCTTTTGCTT TTCAGAGTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033043--FAF1_UBX
IPR012336--Thioredoxin-like_fold
IPR006577--UAS
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50033--UBX

Pfam

PF00789--UBX

SMART

SM00594--UAS
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0005635--C:nuclear envelope
GO:0048471--C:perinuclear region of cytoplasm
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0008219--P:cell death
GO:0007253--P:cytoplasmic sequestering of NF-kappaB
GO:1902043--P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:0031334--P:positive regulation of protein complex assembly
GO:0030155--P:regulation of cell adhesion
GO:0042176--P:regulation of protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002153	Ailuropoda melanoleuca	88.94	0.00e+00	1129.00
IUUC-Apl-004127	Anas platyrhynchos	97.96	0.00e+00	1222.00
IUUC-Aca-005188	Anolis carolinensis	94.03	0.00e+00	1172.00
IUUC-Ame-010696	Astyanax mexicanus	75.42	0.00e+00	845.00
IUUC-Bta-012965	Bos taurus	89.09	0.00e+00	1134.00
IUUC-Cel-018420	Caenorhabditis elegans	28.24	1.00e-29	124.00
IUUC-Cja-019128	Callithrix jacchus	89.59	0.00e+00	1138.00
IUUC-Cfa-021201	Canis familiaris	72.85	0.00e+00	884.00
IUUC-Cpo-021475	Cavia porcellus	91.45	0.00e+00	856.00
IUUC-Csa-024076	Chlorocebus sabaeus	89.71	0.00e+00	1137.00
IUUC-Cho-025067	Choloepus hoffmanni	76.34	0.00e+00	989.00
IUUC-Cin-025663	Ciona intestinalis	44.07	3.00e-70	258.00
IUUC-Csv-025894	Ciona savignyi	33.20	2.00e-67	249.00
IUUC-Dre-027508	Danio rerio	73.58	0.00e+00	937.00
IUUC-Dno-029336	Dasypus novemcinctus	88.79	0.00e+00	1118.00
IUUC-Dor-030218	Dipodomys ordii	82.33	0.00e+00	1016.00
IUUC-Dme-031581	Drosophila melanogaster	34.93	2.00e-89	323.00
IUUC-Ete-032860	Echinops telfairi	71.49	0.00e+00	632.00
IUUC-Eca-034321	Equus caballus	92.01	0.00e+00	991.00
IUUC-Eeu-034844	Erinaceus europaeus	66.13	2.00e-127	449.00
IUUC-Fca-036575	Felis catus	92.29	0.00e+00	688.00
IUUC-Fal-037128	Ficedula albicollis	96.15	0.00e+00	1228.00
IUUC-Gmo-038694	Gadus morhua	74.64	0.00e+00	901.00
IUUC-Gga-040826	Gallus gallus	97.69	0.00e+00	1246.00
IUUC-Gac-042125	Gasterosteus aculeatus	73.66	0.00e+00	966.00
IUUC-Ggo-045254	Gorilla gorilla	89.55	0.00e+00	1139.00
IUUC-Hsa-046722	Homo sapiens	89.40	0.00e+00	1138.00
IUUC-Itr-048149	Ictidomys tridecemlineatus	92.53	2.00e-97	347.00
IUUC-Lch-050312	Latimeria chalumnae	83.50	0.00e+00	689.00
IUUC-Loc-051990	Lepisosteus oculatus	80.43	0.00e+00	966.00
IUUC-Laf-054375	Loxodonta africana	92.84	0.00e+00	694.00
IUUC-Mcc-054627	Macaca mulatta	91.35	0.00e+00	1129.00
IUUC-Meu-056611	Macropus eugenii	67.44	7.00e-122	430.00
IUUC-Mvi-060222	Microbotryum violaceum	34.21	6.40e-02	28.10
IUUC-Mmr-060882	Microcebus murinus	88.48	0.00e+00	1101.00
IUUC-Mdo-061874	Monodelphis domestica	89.69	0.00e+00	1165.00
IUUC-Mmu-063444	Mus musculus	87.86	0.00e+00	1124.00
IUUC-Mpu-065713	Mustela putorius furo	90.72	0.00e+00	1118.00
IUUC-Mlu-068122	Myotis lucifugus	87.69	0.00e+00	1082.00
IUUC-Nle-069025	Nomascus leucogenys	89.09	0.00e+00	1127.00
IUUC-Opr-071089	Ochotona princeps	79.11	0.00e+00	1024.00
IUUC-Ont-072421	Oreochromis niloticus	73.91	0.00e+00	949.00
IUUC-Oan-073092	Ornithorhynchus anatinus	87.86	0.00e+00	867.00
IUUC-Ola-086497	Oryzias latipes	74.02	0.00e+00	952.00
IUUC-Oga-088854	Otolemur garnettii	88.48	0.00e+00	1139.00
IUUC-Oar-090120	Ovis aries	88.94	0.00e+00	1109.00
IUUC-Ptr-091554	Pan troglodytes	89.55	0.00e+00	1139.00
IUUC-Pan-091985	Papio anubis	89.40	0.00e+00	1113.00
IUUC-Psi-093548	Pelodiscus sinensis	96.23	0.00e+00	1166.00
IUUC-Pma-094123	Petromyzon marinus	51.74	6.00e-54	202.00
IUUC-Pfo-096729	Poecilia formosa	72.96	0.00e+00	948.00
IUUC-Pab-097810	Pongo abelii	89.55	0.00e+00	1140.00
IUUC-Pca-101079	Procavia capensis	83.49	0.00e+00	845.00
IUUC-Pva-102534	Pteropus vampyrus	81.48	0.00e+00	854.00
IUUC-Rno-105127	Rattus norvegicus	88.94	0.00e+00	1038.00
IUUC-Sce-106395	Saccharomyces cerevisiae	23.37	4.00e-04	39.30
IUUC-Sha-106667	Sarcophilus harrisii	92.91	0.00e+00	1047.00
IUUC-Sar-113424	Sorex araneus	77.96	2.00e-180	625.00
IUUC-Ssc-115974	Sus scrofa	91.04	0.00e+00	1105.00
IUUC-Tgu-116495	Taeniopygia guttata	96.46	0.00e+00	1232.00
IUUC-Tru-118727	Takifugu rubripes	72.11	0.00e+00	933.00
IUUC-Tsy-118906	Tarsius syrichta	84.02	0.00e+00	1020.00
IUUC-Tni-119717	Tetraodon nigroviridis	74.50	0.00e+00	941.00
IUUC-Tbe-127849	Tupaia belangeri	75.27	0.00e+00	655.00
IUUC-Ttr-128660	Tursiops truncatus	84.97	0.00e+00	1065.00
IUUC-Vpa-130359	Vicugna pacos	90.72	0.00e+00	1125.00
IUUC-Xtr-132212	Xenopus tropicalis	83.87	0.00e+00	735.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence