iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045474

UUCD1 version

UUC-GoG-00714

Ensembl Protein ID

ENSGGOP00000018170.1

UniProt Accession

G3RQU7; G3RQU7_GORGO

Protein Name

Uncharacterized protein

Gene Name

RNF5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000002320.2	ENSGGOT00000002333.2	ENSGGOP00000002283.2
ENSGGOG00000002320.2	ENSGGOT00000027212.1	ENSGGOP00000018170.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.70e-07	31.0	37	78

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iCle  ++  +v  CgH+++  Cl++w         ++ CP+C+
   Q: 37   CNICLETARE-AVVSVCGHLYCWPCLHQW---LETRPERQECPVCK 78
           99******88.888***************...555888889****7 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

KGTWGETKPA MAAAEEEDGG PEGPNRERGG AGATFECNIC LETAREAVVS VCGHLYCWPC 60
LHQWLETRPE RQECPVCKAG ISREKVVPLY GRGSQKPQDP RLKTPPRPQG QRPAPESRGG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAATTCTTTG TGACTGGCAG GCATTCAGAC CAATAGTGAT TAGGAAACCT TGAAGGCTGC 60
CCAACGATCG TGGGCAGGAG GTGGTTTCTG GTTTGTTGGG GCGTGTGTAT GTGTATTTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0016021--C:integral component of membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071712--P:ER-associated misfolded protein catabolic process
GO:0010507--P:negative regulation of autophagy
GO:0031648--P:protein destabilization
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:2000785--P:regulation of autophagosome assembly
GO:0009617--P:response to bacterium

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001155	Aegilops tauschii	48.54	9.00e-24	103.00
IUUC-Aml-001417	Ailuropoda melanoleuca	98.43	5.00e-71	259.00
IUUC-Aca-004254	Anolis carolinensis	75.86	4.00e-36	143.00
IUUC-Ame-011316	Astyanax mexicanus	70.13	4.00e-57	213.00
IUUC-Bta-013109	Bos taurus	98.58	1.00e-79	288.00
IUUC-Bdi-014313	Brachypodium distachyon	54.65	1.00e-23	103.00
IUUC-Bol-016132	Brassica oleracea	43.57	4.00e-27	114.00
IUUC-Bra-017631	Brassica rapa	42.96	7.00e-27	113.00
IUUC-Cja-019902	Callithrix jacchus	97.87	5.00e-79	286.00
IUUC-Cfa-020079	Canis familiaris	97.87	4.00e-79	286.00
IUUC-Cpo-021320	Cavia porcellus	93.41	2.00e-87	314.00
IUUC-Csa-023595	Chlorocebus sabaeus	99.29	3.00e-80	290.00
IUUC-Cme-027164	Cyanidioschyzon merolae	32.24	7.00e-17	80.90
IUUC-Dre-027716	Danio rerio	74.29	1.00e-42	165.00
IUUC-Dno-029843	Dasypus novemcinctus	85.82	1.00e-56	211.00
IUUC-Dor-030170	Dipodomys ordii	97.58	3.00e-69	253.00
IUUC-Eca-033642	Equus caballus	98.78	2.00e-92	331.00
IUUC-Eeu-034778	Erinaceus europaeus	98.29	6.00e-64	235.00
IUUC-Fca-036326	Felis catus	96.45	1.00e-78	285.00
IUUC-Fso-038195	Fusarium solani	40.91	2.00e-10	60.10
IUUC-Gac-042258	Gasterosteus aculeatus	80.80	1.00e-56	211.00
IUUC-Hsa-046046	Homo sapiens	100.00	1.00e-80	291.00
IUUC-Hvu-047124	Hordeum vulgare	54.65	1.00e-23	102.00
IUUC-Itr-048037	Ictidomys tridecemlineatus	98.67	7.00e-85	305.00
IUUC-Lch-050367	Latimeria chalumnae	70.83	7.00e-46	175.00
IUUC-Lpe-051034	Leersia perrieri	45.26	1.00e-25	109.00
IUUC-Laf-053395	Loxodonta africana	96.45	4.00e-78	283.00
IUUC-Mcc-054833	Macaca mulatta	99.29	3.00e-80	290.00
IUUC-Meu-055984	Macropus eugenii	86.08	5.00e-36	143.00
IUUC-Mdo-062437	Monodelphis domestica	88.41	5.00e-83	299.00
IUUC-Mmu-064159	Mus musculus	97.89	4.00e-80	290.00
IUUC-Mac-065053	Musa acuminata	57.65	8.00e-24	103.00
IUUC-Mlu-067689	Myotis lucifugus	90.91	2.00e-84	304.00
IUUC-Nle-069705	Nomascus leucogenys	100.00	1.00e-80	291.00
IUUC-Opr-070392	Ochotona princeps	43.97	2.00e-20	90.90
IUUC-Ont-072482	Oreochromis niloticus	74.83	7.00e-59	219.00
IUUC-Ocu-074208	Oryctolagus cuniculus	97.16	2.00e-78	284.00
IUUC-Oba-075461	Oryza barthii	52.75	3.00e-24	105.00
IUUC-Obr-076382	Oryza brachyantha	56.98	6.00e-25	107.00
IUUC-Ogl-077553	Oryza glaberrima	49.57	1.00e-26	112.00
IUUC-Ogu-078463	Oryza glumaepatula	49.57	1.00e-26	112.00
IUUC-Oin-080177	Oryza indica	49.57	2.00e-26	112.00
IUUC-Olo-080378	Oryza longistaminata	54.65	1.00e-23	103.00
IUUC-Ome-081605	Oryza meridionalis	49.57	2.00e-26	112.00
IUUC-Oni-082458	Oryza nivara	49.57	4.00e-26	112.00
IUUC-Opu-083362	Oryza punctata	58.14	1.00e-25	110.00
IUUC-Oru-084757	Oryza rufipogon	48.74	5.00e-27	114.00
IUUC-Osa-086198	Oryza sativa	48.74	5.00e-27	114.00
IUUC-Ola-086507	Oryzias latipes	68.82	6.00e-62	229.00
IUUC-Olu-087623	Ostreococcus lucimarinus	49.25	2.00e-16	78.60
IUUC-Oga-088912	Otolemur garnettii	99.29	4.00e-80	290.00
IUUC-Oar-090284	Ovis aries	95.30	1.00e-71	261.00
IUUC-Ptr-090919	Pan troglodytes	100.00	3.00e-71	260.00
IUUC-Pan-092843	Papio anubis	99.29	3.00e-80	290.00
IUUC-Pfo-096818	Poecilia formosa	80.16	3.00e-57	214.00
IUUC-Pab-098244	Pongo abelii	99.29	4.00e-80	290.00
IUUC-Pop-099595	Populus trichocarpa	44.14	2.00e-27	115.00
IUUC-Pca-100319	Procavia capensis	96.95	2.00e-82	297.00
IUUC-Pva-102249	Pteropus vampyrus	94.33	1.00e-73	268.00
IUUC-Rno-106042	Rattus norvegicus	97.89	4.00e-80	290.00
IUUC-Smo-109079	Selaginella moellendorffii	48.19	2.00e-22	100.00
IUUC-Sit-110690	Setaria italica	53.57	3.00e-22	98.60
IUUC-Sly-110917	Solanum lycopersicum	52.94	3.00e-25	108.00
IUUC-Stu-112552	Solanum tuberosum	44.44	3.00e-25	108.00
IUUC-Sbi-114275	Sorghum bicolor	54.65	2.00e-23	102.00
IUUC-Ssc-115934	Sus scrofa	99.29	4.00e-80	290.00
IUUC-Tru-118679	Takifugu rubripes	61.73	2.00e-23	100.00
IUUC-Tsy-119615	Tarsius syrichta	95.07	4.00e-75	272.00
IUUC-Tca-121830	Theobroma cacao	48.78	1.00e-25	109.00
IUUC-Tae-123623	Triticum aestivum	54.65	2.00e-23	102.00
IUUC-Tur-126198	Triticum urartu	54.65	1.00e-23	102.00
IUUC-Tbe-127773	Tupaia belangeri	96.45	1.00e-76	278.00
IUUC-Ttr-128690	Tursiops truncatus	97.44	8.00e-64	236.00
IUUC-Vvi-131225	Vitis vinifera	60.00	5.00e-26	110.00
IUUC-Xtr-132608	Xenopus tropicalis	80.00	2.00e-45	174.00
IUUC-Xma-134225	Xiphophorus maculatus	80.16	2.00e-57	214.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence