iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000008860.5	ENSGALT00000014392.5	ENSGALP00000014376.4
ENSGALG00000008860.5	ENSGALT00000051471.1	ENSGALP00000047250.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.20e-10	40.4	95	133
E3 activity/RING/U-box	2.50e-10	40.6	425	473

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C  C+  +++ p++lpCgH+f+++Cl++          + rC+lCr
   Q: 95   CRKCQGFLFE-PVSLPCGHTFCKKCLERD------RAAATRCVLCR 133
           888*******.***************988......99********8 PP

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplte 52
           p+++ C++ + l+ +Pv++p+G+t+  +++e++l+++ k cP++++ l+e
   Q: 425  PSDLDCSLCMRLFYEPVTTPCGHTFCLKCLERCLDHNPK-CPLCKEGLSE 473
           7899**********************************9.*****99865 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MGSRPEPLQA QNLEAASGSR GPEWQALLGR ADALAFGGRL HEALPLYQLA SRQRQLRAEQ 60
LEKLVECLAQ GVRLKEGLPA GSGAPQPRDW DGCRCRKCQG FLFEPVSLPC GHTFCKKCLE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCAGCAGCA TGGGCCGGCG GGGCCGCGCC GCGCCCGCGG CGCCACAGCC TACGCGCCCC 60
GGCGCCCCCG GCCGCCCGCC CGGCTCGCGT TCCCGCTCGT GCTAGAGGCG CCGCCCGCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0802--TPR repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003111--Lon_substr-bd
IPR015947--PUA-like_domain
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51787--LON_N
PS50005--TPR
PS50293--TPR_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02190--LON_substr_bdg
PF13445--zf-RING_UBOX

SMART

SM00464--LON
SM00184--RING
SM00028--TPR

Gene Ontology

GO:0005622--C:intracellular
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

KEGG

gga:422375

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001774	Ailuropoda melanoleuca	76.18	6.00e-154	537.00
IUUC-Apl-003916	Anas platyrhynchos	87.50	0.00e+00	798.00
IUUC-Ang-009643	Aspergillus niger	29.71	1.00e-40	160.00
IUUC-Ame-010881	Astyanax mexicanus	56.99	0.00e+00	706.00
IUUC-Bta-012872	Bos taurus	58.33	0.00e+00	759.00
IUUC-Cfa-020101	Canis familiaris	76.47	2.00e-151	529.00
IUUC-Cpo-022041	Cavia porcellus	55.98	0.00e+00	702.00
IUUC-Csa-024034	Chlorocebus sabaeus	57.20	0.00e+00	746.00
IUUC-Dno-029518	Dasypus novemcinctus	58.60	0.00e+00	709.00
IUUC-Dor-031132	Dipodomys ordii	55.36	0.00e+00	748.00
IUUC-Eca-033382	Equus caballus	58.19	0.00e+00	782.00
IUUC-Fca-035777	Felis catus	64.47	3.00e-178	617.00
IUUC-Fal-036730	Ficedula albicollis	93.81	0.00e+00	1045.00
IUUC-Gac-042201	Gasterosteus aculeatus	52.62	0.00e+00	706.00
IUUC-Ggo-045111	Gorilla gorilla	57.07	0.00e+00	748.00
IUUC-Hsa-045695	Homo sapiens	57.11	0.00e+00	747.00
IUUC-Lch-050429	Latimeria chalumnae	65.74	0.00e+00	945.00
IUUC-Loc-051823	Lepisosteus oculatus	60.30	0.00e+00	791.00
IUUC-Lma-053145	Leptosphaeria maculans	29.48	6.00e-42	165.00
IUUC-Laf-053434	Loxodonta africana	62.82	0.00e+00	667.00
IUUC-Mcc-055249	Macaca mulatta	65.34	4.00e-177	613.00
IUUC-Mga-060131	Meleagris gallopavo	80.25	0.00e+00	872.00
IUUC-Mmr-060749	Microcebus murinus	58.40	0.00e+00	779.00
IUUC-Mdo-062261	Monodelphis domestica	75.23	9.00e-159	553.00
IUUC-Mmu-063219	Mus musculus	52.31	0.00e+00	637.00
IUUC-Mpu-066222	Mustela putorius furo	54.93	0.00e+00	700.00
IUUC-Mlu-067769	Myotis lucifugus	56.48	0.00e+00	752.00
IUUC-Nle-069738	Nomascus leucogenys	61.68	0.00e+00	667.00
IUUC-Ont-072029	Oreochromis niloticus	53.76	0.00e+00	673.00
IUUC-Oan-073179	Ornithorhynchus anatinus	80.08	0.00e+00	805.00
IUUC-Ocu-074884	Oryctolagus cuniculus	56.31	0.00e+00	723.00
IUUC-Oar-089903	Ovis aries	59.08	0.00e+00	763.00
IUUC-Ptr-091238	Pan troglodytes	57.12	0.00e+00	742.00
IUUC-Pan-092379	Papio anubis	59.87	0.00e+00	813.00
IUUC-Psi-093418	Pelodiscus sinensis	80.91	0.00e+00	729.00
IUUC-Pno-094889	Phaeosphaeria nodorum	32.46	1.00e-41	163.00
IUUC-Pfo-097284	Poecilia formosa	51.96	0.00e+00	698.00
IUUC-Pab-098343	Pongo abelii	59.38	0.00e+00	816.00
IUUC-Pca-100905	Procavia capensis	52.20	2.00e-159	555.00
IUUC-Pva-102242	Pteropus vampyrus	54.59	0.00e+00	671.00
IUUC-Pte-104214	Pyrenophora teres	30.92	2.00e-39	156.00
IUUC-Pyt-104565	Pyrenophora triticirepentis	30.64	2.00e-39	156.00
IUUC-Rno-105899	Rattus norvegicus	59.95	0.00e+00	818.00
IUUC-Sha-107565	Sarcophilus harrisii	50.79	0.00e+00	683.00
IUUC-Sja-107742	Schizosaccharomyces japonicus	35.43	4.00e-32	132.00
IUUC-Spo-108344	Schizosaccharomyces pombe	33.49	6.00e-26	111.00
IUUC-Ssc-115705	Sus scrofa	57.44	0.00e+00	767.00
IUUC-Tgu-116978	Taeniopygia guttata	80.96	0.00e+00	1051.00
IUUC-Tsy-118988	Tarsius syrichta	62.75	0.00e+00	656.00
IUUC-Tbe-127563	Tupaia belangeri	71.78	5.00e-114	404.00
IUUC-Ttr-128875	Tursiops truncatus	77.41	7.00e-149	521.00
IUUC-Vpa-130779	Vicugna pacos	81.53	4.00e-138	484.00
IUUC-Xtr-132508	Xenopus tropicalis	61.48	0.00e+00	842.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence