iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049684

Ensembl Protein ID

ENSLACP00000012395.1

UniProt Accession

H3ARX4; H3ARX4_LATCH

Genbank Protein ID

ENSLACP00000012395

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

AFYH01039464

Gene Name

NSD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000010915.1	ENSLACT00000012488.1	ENSLACP00000012395.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	5.10e-14	52.4	1687	1727

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C vC egg+    l++Ce C  +fH +Cl++     +p+ + w+C++C+
   Q: 1687 WCFVCSEGGS----LLCCESCPAAFHRECLNID----MPEGN-WYCNDCK 1727
           8*********....*******************....99996.******8 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MDQAHELCRI NCLLPFSNPV ELEAPDNKQF NGRDPGNPFE PGNGCTMELP AAFQNTASKS 60
AQDHSACYSP LRRLQDLASM INMDYLDING SKDGAKPVQA PGKIHLRPEV PQAYTTLKTD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATCAAG CACATGAACT ATGTAGGATA AATTGTCTTT TACCATTTTC CAATCCTGTG 60
GAGTTAGAAG CTCCAGATAA CAAACAATTT AATGGAAGAG ATCCAGGAAA CCCATTTGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR006560--AWS_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51215--AWS
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00855--PWWP
PF00856--SET

SMART

SM00570--AWS
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000229	Aegilops tauschii	54.17	3.00e-04	42.00
IUUC-Aml-001795	Ailuropoda melanoleuca	65.87	0.00e+00	1396.00
IUUC-Apl-003953	Anas platyrhynchos	55.13	0.00e+00	1443.00
IUUC-Aca-005339	Anolis carolinensis	80.39	0.00e+00	1274.00
IUUC-Bta-012966	Bos taurus	56.30	0.00e+00	1500.00
IUUC-Bol-016001	Brassica oleracea	30.43	8.00e-17	83.20
IUUC-Bra-017864	Brassica rapa	29.89	1.00e-15	79.30
IUUC-Cja-018780	Callithrix jacchus	57.22	0.00e+00	1483.00
IUUC-Cfa-020975	Canis familiaris	57.15	0.00e+00	1483.00
IUUC-Cpo-021331	Cavia porcellus	66.12	0.00e+00	1396.00
IUUC-Csa-024226	Chlorocebus sabaeus	55.32	0.00e+00	1486.00
IUUC-Cho-024464	Choloepus hoffmanni	36.78	1.00e-144	508.00
IUUC-Dre-027488	Danio rerio	78.35	0.00e+00	1193.00
IUUC-Dno-029230	Dasypus novemcinctus	54.88	0.00e+00	1414.00
IUUC-Dor-031016	Dipodomys ordii	73.58	0.00e+00	981.00
IUUC-Eca-033591	Equus caballus	56.69	0.00e+00	1477.00
IUUC-Fca-035791	Felis catus	54.38	0.00e+00	1482.00
IUUC-Fal-037378	Ficedula albicollis	56.57	0.00e+00	1404.00
IUUC-Gmo-038919	Gadus morhua	71.20	0.00e+00	905.00
IUUC-Gga-040881	Gallus gallus	54.60	0.00e+00	1425.00
IUUC-Gac-041378	Gasterosteus aculeatus	77.22	0.00e+00	1018.00
IUUC-Hsa-046436	Homo sapiens	57.19	0.00e+00	1492.00
IUUC-Itr-048194	Ictidomys tridecemlineatus	56.88	0.00e+00	1497.00
IUUC-Lpe-051201	Leersia perrieri	29.94	2.00e-12	67.40
IUUC-Laf-054046	Loxodonta africana	54.92	0.00e+00	1498.00
IUUC-Mcc-055593	Macaca mulatta	56.96	0.00e+00	1488.00
IUUC-Mga-059756	Meleagris gallopavo	54.78	0.00e+00	1424.00
IUUC-Mmr-061182	Microcebus murinus	55.74	0.00e+00	1482.00
IUUC-Mdo-061984	Monodelphis domestica	56.23	0.00e+00	1392.00
IUUC-Mmu-063605	Mus musculus	65.24	0.00e+00	1419.00
IUUC-Mpu-066446	Mustela putorius furo	54.73	0.00e+00	1487.00
IUUC-Mlu-067261	Myotis lucifugus	54.17	0.00e+00	1481.00
IUUC-Nle-069818	Nomascus leucogenys	56.63	0.00e+00	1477.00
IUUC-Opr-070842	Ochotona princeps	65.56	0.00e+00	1262.00
IUUC-Ont-072448	Oreochromis niloticus	74.63	0.00e+00	1092.00
IUUC-Oan-073496	Ornithorhynchus anatinus	72.26	0.00e+00	1387.00
IUUC-Ocu-074918	Oryctolagus cuniculus	54.52	0.00e+00	1508.00
IUUC-Obr-076753	Oryza brachyantha	54.84	1.00e-07	53.10
IUUC-Ola-087518	Oryzias latipes	75.40	0.00e+00	994.00
IUUC-Oga-088743	Otolemur garnettii	55.96	0.00e+00	1506.00
IUUC-Oar-090265	Ovis aries	56.02	0.00e+00	1496.00
IUUC-Ptr-090521	Pan troglodytes	56.94	0.00e+00	1490.00
IUUC-Psi-093245	Pelodiscus sinensis	55.07	0.00e+00	1363.00
IUUC-Pfo-096066	Poecilia formosa	67.47	0.00e+00	1169.00
IUUC-Pab-098644	Pongo abelii	57.15	0.00e+00	1475.00
IUUC-Pva-103094	Pteropus vampyrus	86.37	0.00e+00	1063.00
IUUC-Rno-105803	Rattus norvegicus	56.73	0.00e+00	1464.00
IUUC-Sha-107278	Sarcophilus harrisii	66.20	0.00e+00	1397.00
IUUC-Sar-113402	Sorex araneus	81.78	0.00e+00	984.00
IUUC-Ssc-116193	Sus scrofa	56.98	0.00e+00	1470.00
IUUC-Tgu-116532	Taeniopygia guttata	85.00	0.00e+00	1176.00
IUUC-Tru-117988	Takifugu rubripes	77.57	0.00e+00	1151.00
IUUC-Tsy-118830	Tarsius syrichta	49.58	0.00e+00	1636.00
IUUC-Tni-120452	Tetraodon nigroviridis	59.25	0.00e+00	908.00
IUUC-Tca-121456	Theobroma cacao	31.75	2.00e-19	90.90
IUUC-Tae-124697	Triticum aestivum	54.17	2.00e-04	42.00
IUUC-Xma-133606	Xiphophorus maculatus	77.25	0.00e+00	1102.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence