iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107392

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01024970

Gene Name

TRIM35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000006418.1	ENSSHAT00000007445.1	ENSSHAP00000007383.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.80e-07	31.3	16	79
E3 activity/RING/RING	7.50e-08	32.9	21	59

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk.tcPvtrqplteedlvPnltlrrli 65
            ee+lC+I ++++rd v+l +G+ + r ++ ++ + +    cPv +++ +++ + Pn +l++ +
   Q: 16   KEELLCAICYDPFRDAVTLRCGHNFCRGCVGRCWELQDApACPVFKERAAPKHFQPNQALKDGV 79
           689*****************************997766669*******************9855 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPl 44
           CaiC+++f+d  ++l+CgH f++ C+  +w     + + +  CP+
   Q: 21   CAICYDPFRD-AVTLRCGHNFCRGCVgRCW-----ELQDAPACPV 59
           ********99.999************9999.....7888888997 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MEPGPGESAG LSPSFKEELL CAICYDPFRD AVTLRCGHNF CRGCVGRCWE LQDAPACPVF 60
KERAAPKHFQ PNQALKDGVE KKIFRKAGLC RTQPIYYSRA CALVHHKKIS AVCTHKHIII 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGCCGG GACCGGGCGA GTCCGCTGGG CTATCGCCCT CCTTCAAGGA GGAGCTGCTC 60
TGCGCCATCT GCTACGACCC GTTCCGCGAC GCGGTGACTC TGCGCTGCGG CCACAACTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00097--zf-C3HC4

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0045930--P:negative regulation of mitotic cell cycle
GO:1902187--P:negative regulation of viral release from host cell
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001788	Ailuropoda melanoleuca	70.02	0.00e+00	709.00
IUUC-Apl-003958	Anas platyrhynchos	48.56	8.00e-114	403.00
IUUC-Aca-005199	Anolis carolinensis	43.02	7.00e-110	390.00
IUUC-Bta-013359	Bos taurus	68.39	0.00e+00	676.00
IUUC-Cja-018900	Callithrix jacchus	58.61	9.00e-169	586.00
IUUC-Cfa-020685	Canis familiaris	70.82	0.00e+00	713.00
IUUC-Cpo-022253	Cavia porcellus	64.11	0.00e+00	644.00
IUUC-Csa-023777	Chlorocebus sabaeus	69.62	0.00e+00	714.00
IUUC-Dno-029065	Dasypus novemcinctus	66.80	0.00e+00	691.00
IUUC-Dor-030248	Dipodomys ordii	59.32	6.00e-91	326.00
IUUC-Ete-033183	Echinops telfairi	56.91	2.00e-157	548.00
IUUC-Eca-033263	Equus caballus	67.24	3.00e-179	620.00
IUUC-Eeu-034699	Erinaceus europaeus	74.26	6.00e-108	384.00
IUUC-Fca-036366	Felis catus	68.41	0.00e+00	692.00
IUUC-Fal-037257	Ficedula albicollis	51.54	2.00e-131	462.00
IUUC-Gga-041125	Gallus gallus	56.73	2.00e-110	392.00
IUUC-Ggo-045233	Gorilla gorilla	78.34	1.00e-151	528.00
IUUC-Hsa-046042	Homo sapiens	69.82	0.00e+00	714.00
IUUC-Itr-048751	Ictidomys tridecemlineatus	68.18	0.00e+00	679.00
IUUC-Laf-054322	Loxodonta africana	69.36	0.00e+00	684.00
IUUC-Mcc-055555	Macaca mulatta	67.59	0.00e+00	694.00
IUUC-Meu-055900	Macropus eugenii	81.74	0.00e+00	793.00
IUUC-Mga-059380	Meleagris gallopavo	47.49	1.00e-79	289.00
IUUC-Mmr-061296	Microcebus murinus	66.80	0.00e+00	667.00
IUUC-Mdo-062811	Monodelphis domestica	79.07	0.00e+00	778.00
IUUC-Mmu-063718	Mus musculus	61.71	1.00e-178	619.00
IUUC-Mpu-066219	Mustela putorius furo	69.01	0.00e+00	684.00
IUUC-Mlu-067033	Myotis lucifugus	67.81	0.00e+00	686.00
IUUC-Nle-069806	Nomascus leucogenys	68.95	0.00e+00	661.00
IUUC-Opr-070248	Ochotona princeps	60.12	1.00e-165	576.00
IUUC-Oan-073364	Ornithorhynchus anatinus	69.35	3.00e-102	364.00
IUUC-Ocu-074572	Oryctolagus cuniculus	69.01	0.00e+00	706.00
IUUC-Oga-088378	Otolemur garnettii	66.20	0.00e+00	663.00
IUUC-Oar-089516	Ovis aries	67.98	0.00e+00	669.00
IUUC-Ptr-091313	Pan troglodytes	69.82	0.00e+00	714.00
IUUC-Pan-092877	Papio anubis	69.62	0.00e+00	714.00
IUUC-Psi-093928	Pelodiscus sinensis	53.70	5.00e-141	494.00
IUUC-Pab-098624	Pongo abelii	69.62	0.00e+00	708.00
IUUC-Pca-100469	Procavia capensis	64.60	0.00e+00	641.00
IUUC-Pva-103227	Pteropus vampyrus	69.01	0.00e+00	695.00
IUUC-Rno-105778	Rattus norvegicus	61.10	3.00e-177	614.00
IUUC-Ssc-115739	Sus scrofa	70.04	0.00e+00	689.00
IUUC-Tbe-127926	Tupaia belangeri	73.29	1.00e-117	416.00
IUUC-Ttr-129293	Tursiops truncatus	69.22	0.00e+00	690.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence