iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000019967.2	ENSMMUT00000028064.2	ENSMMUP00000026256.1
ENSMMUG00000019967.2	ENSMMUT00000059961.1	ENSMMUP00000052777.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.80e-18	67.1	212	279
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	8.10e-07	28.4	311	337

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dvil+vg+++++ah++vL++ S++F a+f+++  e k ++++++++++p ++ +l++F Ytg l+++e
   Q: 212  CDVILIVGNRKIPAHRLVLSSVSDYFAAMFTSDVCEAK-QEEIKMEGIDPNALWDLVQFAYTGCLELKE 279
           9************************************9.**************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfi 27
           ++Nclgi++fAd+ +c +L+++a++++
   Q: 311  PSNCLGIRAFADAQGCIELMKVAHSYT 337
           89***********************95 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MSGSGRKDFD VKHILRLRWK LFSHPSPSTG SPAGGGCLQQ DGSGSFEHWG PSQSRLLKSH 60
ERSGVSTFWK KPSSSSSSSS SPSSSSSSFN PLNGTLLPVA TRLQQGAPGQ GTQQPARTLF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAGGCT CTGGGCGAAA AGACTTCGAT GTGAAGCACA TTCTGCGACT CCGCTGGAAA 60
CTCTTCAGCC ACCCGTCACC GTCCACCGGC AGCCCGGCGG GGGGAGGCTG CCTGCAACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0030425--C:dendrite
GO:0043025--C:neuronal cell body
GO:0007628--P:adult walking behavior
GO:0021680--P:cerebellar Purkinje cell layer development
GO:0016358--P:dendrite development
GO:0016567--P:protein ubiquitination

KEGG

mcc:708779

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001478	Ailuropoda melanoleuca	96.26	0.00e+00	1350.00
IUUC-Apl-003408	Anas platyrhynchos	95.89	0.00e+00	1109.00
IUUC-Aca-004384	Anolis carolinensis	86.14	0.00e+00	1249.00
IUUC-Bta-012684	Bos taurus	98.63	0.00e+00	1135.00
IUUC-Cja-019103	Callithrix jacchus	98.66	0.00e+00	1373.00
IUUC-Cfa-020670	Canis familiaris	98.05	0.00e+00	1199.00
IUUC-Cpo-021951	Cavia porcellus	98.80	0.00e+00	1138.00
IUUC-Csa-023607	Chlorocebus sabaeus	99.66	0.00e+00	1143.00
IUUC-Cho-024648	Choloepus hoffmanni	87.38	0.00e+00	1137.00
IUUC-Dno-029854	Dasypus novemcinctus	95.46	0.00e+00	1312.00
IUUC-Dor-030497	Dipodomys ordii	79.63	0.00e+00	981.00
IUUC-Eca-033525	Equus caballus	96.53	0.00e+00	1379.00
IUUC-Fca-035490	Felis catus	98.80	0.00e+00	1134.00
IUUC-Fal-037099	Ficedula albicollis	97.68	0.00e+00	1107.00
IUUC-Gga-041081	Gallus gallus	86.36	0.00e+00	1193.00
IUUC-Gma-043533	Glycine max	32.64	1.00e-38	154.00
IUUC-Ggo-044717	Gorilla gorilla	99.47	0.00e+00	1377.00
IUUC-Hsa-045726	Homo sapiens	99.47	0.00e+00	1377.00
IUUC-Itr-048921	Ictidomys tridecemlineatus	98.13	0.00e+00	1360.00
IUUC-Loc-052321	Lepisosteus oculatus	76.64	0.00e+00	1097.00
IUUC-Laf-054378	Loxodonta africana	96.13	0.00e+00	1335.00
IUUC-Mmr-061255	Microcebus murinus	82.00	0.00e+00	1103.00
IUUC-Mdo-062369	Monodelphis domestica	93.59	0.00e+00	1333.00
IUUC-Mmu-063334	Mus musculus	95.47	0.00e+00	1330.00
IUUC-Nle-069856	Nomascus leucogenys	99.33	0.00e+00	1375.00
IUUC-Ocu-074469	Oryctolagus cuniculus	96.13	0.00e+00	1333.00
IUUC-Obr-076181	Oryza brachyantha	31.38	1.00e-35	145.00
IUUC-Oin-080100	Oryza indica	29.51	4.00e-34	139.00
IUUC-Opu-083716	Oryza punctata	31.02	2.00e-32	134.00
IUUC-Olu-087696	Ostreococcus lucimarinus	36.36	7.00e-33	133.00
IUUC-Oga-088528	Otolemur garnettii	97.73	0.00e+00	1189.00
IUUC-Oar-089603	Ovis aries	98.46	0.00e+00	1131.00
IUUC-Ptr-090657	Pan troglodytes	99.06	0.00e+00	1373.00
IUUC-Psi-092962	Pelodiscus sinensis	96.23	0.00e+00	1114.00
IUUC-Pab-097812	Pongo abelii	98.93	0.00e+00	1346.00
IUUC-Pva-103042	Pteropus vampyrus	95.76	0.00e+00	1336.00
IUUC-Sbi-114612	Sorghum bicolor	28.81	1.00e-34	141.00
IUUC-Ssc-115880	Sus scrofa	98.63	0.00e+00	1134.00
IUUC-Tgu-116624	Taeniopygia guttata	94.79	0.00e+00	979.00
IUUC-Tsy-119339	Tarsius syrichta	90.51	0.00e+00	1221.00
IUUC-Tbe-127398	Tupaia belangeri	100.00	0.00e+00	680.00
IUUC-Ttr-129024	Tursiops truncatus	95.87	0.00e+00	1399.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence