iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-098222

Ensembl Protein ID

ENSPPYP00000015093.2

UniProt Accession

H2P9L1; H2P9L1_PONAB

Genbank Protein ID

ENSPPYP00000015093

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01035906

Gene Name

HCLS1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000013495.2	ENSPPYT00000015696.2	ENSPPYP00000015093.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.10e-12	46.3	461	512

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
            +lydy+++ +deL++   dv++ i  e  degW++g    +g  GlfP+n+v+ l
   Q: 461  VALYDYQGEGSDELSFDPDDVITDI--EMVDEGWWRG--RCHGHFGLFPANYVKLL 512
           58**********************9..9*********..8*************977 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

GTEAAAQFLT PKWQQPERES VWTREAGHLE QRLAQVEMWK SVVGHDVSVS VETQGDDWDT 60
DPDFVNDISE KEQRWGAKTI EGSGRTEHIN IHQLRNKVSA EHDVLKKKEM ESGPKASHGY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGGAACTGA AGCAGCAGCT CAGTTTCTCA CTCCGAAGTG GCAGCAGCCA GAGAGGGAGT 60
CGGTGTGGAC GCGAGAAGCC GGGCACTTAG AACAGAGGCT CGCACAGGTG GAGGTGGGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028534--HS1
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005667--C:transcription factor complex
GO:0030041--P:actin filament polymerization
GO:0071345--P:cellular response to cytokine stimulus
GO:0030218--P:erythrocyte differentiation
GO:2000107--P:negative regulation of leukocyte apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0008284--P:positive regulation of cell proliferation
GO:0030854--P:positive regulation of granulocyte differentiation
GO:0045651--P:positive regulation of macrophage differentiation
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0014068--P:positive regulation of phosphatidylinositol 3-kinase signaling
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0042531--P:positive regulation of tyrosine phosphorylation of STAT protein
GO:0030833--P:regulation of actin filament polymerization
GO:0009725--P:response to hormone

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001194	Ailuropoda melanoleuca	85.30	0.00e+00	735.00
IUUC-Bta-012591	Bos taurus	85.60	0.00e+00	683.00
IUUC-Cja-019982	Callithrix jacchus	92.29	0.00e+00	739.00
IUUC-Cfa-020262	Canis familiaris	82.65	0.00e+00	655.00
IUUC-Cpo-021362	Cavia porcellus	86.13	0.00e+00	656.00
IUUC-Csa-023911	Chlorocebus sabaeus	95.48	0.00e+00	769.00
IUUC-Dor-030437	Dipodomys ordii	77.15	5.00e-172	597.00
IUUC-Ete-033160	Echinops telfairi	74.89	3.00e-155	541.00
IUUC-Eca-033269	Equus caballus	83.33	0.00e+00	716.00
IUUC-Eeu-035032	Erinaceus europaeus	71.65	1.00e-121	429.00
IUUC-Fca-035999	Felis catus	80.80	0.00e+00	746.00
IUUC-Fal-037107	Ficedula albicollis	50.47	6.00e-123	434.00
IUUC-Ggo-044505	Gorilla gorilla	90.29	0.00e+00	743.00
IUUC-Hsa-046728	Homo sapiens	97.46	0.00e+00	635.00
IUUC-Itr-048592	Ictidomys tridecemlineatus	67.94	6.00e-168	583.00
IUUC-Laf-054202	Loxodonta africana	82.00	0.00e+00	679.00
IUUC-Mcc-055824	Macaca mulatta	93.07	0.00e+00	762.00
IUUC-Mmr-061281	Microcebus murinus	77.43	8.00e-176	609.00
IUUC-Mdo-062515	Monodelphis domestica	68.76	1.00e-151	529.00
IUUC-Mmu-064341	Mus musculus	81.26	0.00e+00	678.00
IUUC-Mpu-066565	Mustela putorius furo	87.61	0.00e+00	701.00
IUUC-Mlu-066942	Myotis lucifugus	81.15	0.00e+00	690.00
IUUC-Nle-069436	Nomascus leucogenys	97.23	0.00e+00	830.00
IUUC-Opr-070288	Ochotona princeps	79.92	9.00e-172	596.00
IUUC-Ocu-074686	Oryctolagus cuniculus	84.84	0.00e+00	635.00
IUUC-Ola-086894	Oryzias latipes	59.79	1.00e-95	343.00
IUUC-Oga-088585	Otolemur garnettii	78.85	0.00e+00	680.00
IUUC-Oar-089686	Ovis aries	85.63	0.00e+00	718.00
IUUC-Ptr-090461	Pan troglodytes	98.31	0.00e+00	641.00
IUUC-Pan-091887	Papio anubis	97.06	0.00e+00	753.00
IUUC-Psi-093785	Pelodiscus sinensis	51.93	3.00e-140	491.00
IUUC-Pca-100668	Procavia capensis	81.25	0.00e+00	674.00
IUUC-Pva-102767	Pteropus vampyrus	72.82	8.00e-170	590.00
IUUC-Rno-106001	Rattus norvegicus	83.72	0.00e+00	685.00
IUUC-Sar-113338	Sorex araneus	75.98	9.00e-173	599.00
IUUC-Ssc-116027	Sus scrofa	84.62	0.00e+00	720.00
IUUC-Tgu-117472	Taeniopygia guttata	58.16	5.00e-153	534.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence