iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090310

Ensembl Protein ID

ENSOARP00000001587.1

UniProt Accession

W5NTU3; W5NTU3_SHEEP

Genbank Protein ID

ENSOARP00000001587

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01073960

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000001521.1	ENSOART00000001630.1	ENSOARP00000001587.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	76.49	0.00e+00	793.00	IUUC-Hsa-046952

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

RGLGGAAALM AAASVTPPGS LDLLQPGFSK TLLGTKLEDK YLCSACKNVL RRPFQAQCGH 60
RYCSFCLSSI LSSGPQSCAA CVHEGIYEEG VSILESSSAF PDNAARREVE SLPAVCPSEG 120

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Nucleotide Sequence
(Fasta)

GAAGGAACCT GCGTGGGAAT CCCCCACGTT GCCCGACGAC CGGAGTGAGT CATCCCTTCC 60
CAGCCTGCCA GGACCGAGGT GTCACCTTCT GAGCTGGTGG TGGATGTGGG CCGGCCACTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027133--TRAF2
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:1990597--C:AIP1-IRE1 complex
GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005829--C:cytosol
GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:0045121--C:membrane raft
GO:0097057--C:TRAF2-GSTP1 complex
GO:0000151--C:ubiquitin ligase complex
GO:0012506--C:vesicle membrane
GO:0046625--F:sphingolipid binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0043623--P:cellular protein complex assembly
GO:0071732--P:cellular response to nitric oxide
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:1903721--P:positive regulation of I-kappaB phosphorylation
GO:0032743--P:positive regulation of interleukin-2 production
GO:0043507--P:positive regulation of JUN kinase activity
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0002726--P:positive regulation of T cell cytokine production
GO:1903265--P:positive regulation of tumor necrosis factor-mediated signaling pathway
GO:0097300--P:programmed necrotic cell death
GO:0051865--P:protein autoubiquitination
GO:0030163--P:protein catabolic process
GO:0070207--P:protein homotrimerization
GO:0070534--P:protein K63-linked ubiquitination
GO:0051023--P:regulation of immunoglobulin secretion
GO:0033209--P:tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000744	Aegilops tauschii	24.58	4.00e-05	44.30
IUUC-Aml-002344	Ailuropoda melanoleuca	78.54	0.00e+00	801.00
IUUC-Apl-004202	Anas platyrhynchos	64.90	0.00e+00	704.00
IUUC-Aca-005029	Anolis carolinensis	64.84	2.00e-86	312.00
IUUC-Ame-011841	Astyanax mexicanus	52.83	1.00e-172	599.00
IUUC-Bta-013180	Bos taurus	85.25	0.00e+00	848.00
IUUC-Cja-019813	Callithrix jacchus	76.86	0.00e+00	795.00
IUUC-Cfa-021205	Canis familiaris	77.20	0.00e+00	774.00
IUUC-Cpo-021346	Cavia porcellus	75.72	0.00e+00	781.00
IUUC-Csa-023809	Chlorocebus sabaeus	73.83	0.00e+00	683.00
IUUC-Dre-027669	Danio rerio	51.95	9.00e-156	543.00
IUUC-Dno-029458	Dasypus novemcinctus	72.43	0.00e+00	752.00
IUUC-Dor-030338	Dipodomys ordii	73.06	0.00e+00	701.00
IUUC-Eca-034401	Equus caballus	79.09	0.00e+00	823.00
IUUC-Eeu-034668	Erinaceus europaeus	85.12	1.00e-58	220.00
IUUC-Fca-036057	Felis catus	78.74	0.00e+00	805.00
IUUC-Fal-037560	Ficedula albicollis	86.81	5.00e-97	348.00
IUUC-Gmo-038964	Gadus morhua	51.70	2.00e-154	538.00
IUUC-Gga-040425	Gallus gallus	64.19	0.00e+00	682.00
IUUC-Gac-041908	Gasterosteus aculeatus	55.64	6.00e-165	573.00
IUUC-Ggo-044606	Gorilla gorilla	70.36	0.00e+00	706.00
IUUC-Hsa-046952	Homo sapiens	76.58	0.00e+00	793.00
IUUC-Itr-049016	Ictidomys tridecemlineatus	66.92	0.00e+00	639.00
IUUC-Lch-049571	Latimeria chalumnae	60.25	2.00e-90	326.00
IUUC-Loc-051973	Lepisosteus oculatus	55.15	4.00e-159	554.00
IUUC-Laf-053815	Loxodonta africana	72.87	0.00e+00	719.00
IUUC-Mcc-054888	Macaca mulatta	76.58	0.00e+00	791.00
IUUC-Meu-056547	Macropus eugenii	59.57	1.00e-150	526.00
IUUC-Mga-059819	Meleagris gallopavo	62.72	0.00e+00	662.00
IUUC-Mdo-062570	Monodelphis domestica	69.83	0.00e+00	741.00
IUUC-Mmu-063133	Mus musculus	72.68	0.00e+00	744.00
IUUC-Mpu-065802	Mustela putorius furo	78.39	0.00e+00	795.00
IUUC-Nle-070155	Nomascus leucogenys	76.86	0.00e+00	796.00
IUUC-Opr-070856	Ochotona princeps	60.00	8.00e-73	267.00
IUUC-Ont-071930	Oreochromis niloticus	55.43	8.00e-173	600.00
IUUC-Ola-087397	Oryzias latipes	54.87	4.00e-171	594.00
IUUC-Oga-088109	Otolemur garnettii	75.53	0.00e+00	783.00
IUUC-Ptr-090643	Pan troglodytes	77.06	0.00e+00	797.00
IUUC-Pan-091933	Papio anubis	76.97	0.00e+00	791.00
IUUC-Psi-093681	Pelodiscus sinensis	64.57	0.00e+00	669.00
IUUC-Pfo-096148	Poecilia formosa	53.66	1.00e-170	592.00
IUUC-Pab-098631	Pongo abelii	77.06	0.00e+00	800.00
IUUC-Pca-100582	Procavia capensis	83.45	2.00e-70	259.00
IUUC-Pva-102396	Pteropus vampyrus	82.85	2.00e-118	419.00
IUUC-Rno-106120	Rattus norvegicus	80.00	1.00e-113	403.00
IUUC-Sha-106493	Sarcophilus harrisii	71.18	0.00e+00	756.00
IUUC-Sar-113570	Sorex araneus	92.82	9.00e-99	353.00
IUUC-Ssc-115843	Sus scrofa	79.31	0.00e+00	801.00
IUUC-Tgu-117144	Taeniopygia guttata	58.63	1.00e-165	575.00
IUUC-Tru-117853	Takifugu rubripes	54.38	8.00e-171	593.00
IUUC-Tni-120256	Tetraodon nigroviridis	55.70	2.00e-173	602.00
IUUC-Tae-123531	Triticum aestivum	24.58	4.00e-05	44.30
IUUC-Ttr-129246	Tursiops truncatus	77.69	0.00e+00	790.00
IUUC-Xtr-132279	Xenopus tropicalis	75.82	6.00e-85	308.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence