iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-117144

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01048826

Gene Name

TRAF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000002428.1	ENSTGUT00000002534.1	ENSTGUP00000002510.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	70.28	0.00e+00	706.00	IUUC-Hsa-046952

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MAAANSSPPG SLDLNQPGFA KEILGTKLEV KYLCSDCKNI LRRPFQAQCG HRYCSYCLKK 60
IISAGPQKCA SCIQEGIYEE GISILETSSA FPDNAARREV ESLPAVCINS GCNWKGTIKE 120

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Nucleotide Sequence
(Fasta)

ATGGCAGCAG CAAACTCTTC TCCACCTGGT TCTCTGGATC TAAACCAGCC TGGCTTTGCA 60
AAGGAGATCT TGGGAACTAA ACTGGAGGTC AAATACCTGT GCTCCGATTG CAAGAACATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027133--TRAF2
IPR032070--TRAF_BIRC3-bd
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF16673--TRAF_BIRC3_bd
PF00097--zf-C3HC4

SMART

SM00061--MATH

Gene Ontology

GO:1990597--C:AIP1-IRE1 complex
GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005829--C:cytosol
GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:0045121--C:membrane raft
GO:0097057--C:TRAF2-GSTP1 complex
GO:0000151--C:ubiquitin ligase complex
GO:0012506--C:vesicle membrane
GO:0046625--F:sphingolipid binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0043623--P:cellular protein complex assembly
GO:0071732--P:cellular response to nitric oxide
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:1903721--P:positive regulation of I-kappaB phosphorylation
GO:0032743--P:positive regulation of interleukin-2 production
GO:0043507--P:positive regulation of JUN kinase activity
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0002726--P:positive regulation of T cell cytokine production
GO:1903265--P:positive regulation of tumor necrosis factor-mediated signaling pathway
GO:0097300--P:programmed necrotic cell death
GO:0051865--P:protein autoubiquitination
GO:0030163--P:protein catabolic process
GO:0070207--P:protein homotrimerization
GO:0070534--P:protein K63-linked ubiquitination
GO:0051023--P:regulation of immunoglobulin secretion
GO:0033209--P:tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002344	Ailuropoda melanoleuca	65.47	0.00e+00	664.00
IUUC-Apl-004202	Anas platyrhynchos	74.95	0.00e+00	794.00
IUUC-Aca-005029	Anolis carolinensis	51.71	1.00e-116	412.00
IUUC-Ame-011841	Astyanax mexicanus	44.06	3.00e-127	448.00
IUUC-Bta-013180	Bos taurus	66.54	0.00e+00	665.00
IUUC-Cja-019813	Callithrix jacchus	69.88	0.00e+00	706.00
IUUC-Cfa-021205	Canis familiaris	69.44	0.00e+00	671.00
IUUC-Cpo-021346	Cavia porcellus	69.49	0.00e+00	691.00
IUUC-Csa-023809	Chlorocebus sabaeus	69.09	2.00e-174	604.00
IUUC-Dre-027669	Danio rerio	53.73	9.00e-154	536.00
IUUC-Dno-029458	Dasypus novemcinctus	65.30	0.00e+00	687.00
IUUC-Dor-030338	Dipodomys ordii	67.45	0.00e+00	668.00
IUUC-Eca-034401	Equus caballus	69.14	0.00e+00	697.00
IUUC-Eeu-034668	Erinaceus europaeus	84.21	2.00e-77	282.00
IUUC-Fca-036057	Felis catus	67.17	0.00e+00	687.00
IUUC-Fal-037560	Ficedula albicollis	82.35	0.00e+00	797.00
IUUC-Gmo-038964	Gadus morhua	57.11	2.00e-161	561.00
IUUC-Gga-040425	Gallus gallus	76.91	0.00e+00	798.00
IUUC-Gac-041908	Gasterosteus aculeatus	59.17	1.00e-166	579.00
IUUC-Ggo-044606	Gorilla gorilla	62.80	6.00e-177	613.00
IUUC-Hsa-046952	Homo sapiens	70.28	0.00e+00	706.00
IUUC-Itr-049016	Ictidomys tridecemlineatus	60.38	3.00e-162	564.00
IUUC-Lch-049571	Latimeria chalumnae	54.16	2.00e-168	585.00
IUUC-Loc-051973	Lepisosteus oculatus	56.86	2.00e-163	568.00
IUUC-Laf-053815	Loxodonta africana	67.44	0.00e+00	672.00
IUUC-Mcc-054888	Macaca mulatta	69.79	0.00e+00	704.00
IUUC-Meu-056547	Macropus eugenii	84.00	3.00e-134	471.00
IUUC-Mga-059819	Meleagris gallopavo	79.64	0.00e+00	786.00
IUUC-Mdo-062570	Monodelphis domestica	72.27	0.00e+00	705.00
IUUC-Mmu-063133	Mus musculus	68.25	0.00e+00	659.00
IUUC-Mpu-065802	Mustela putorius furo	66.28	0.00e+00	678.00
IUUC-Nle-070155	Nomascus leucogenys	70.28	0.00e+00	711.00
IUUC-Opr-070856	Ochotona princeps	71.05	5.00e-95	341.00
IUUC-Ont-071930	Oreochromis niloticus	59.38	3.00e-176	610.00
IUUC-Ola-087397	Oryzias latipes	56.04	7.00e-171	593.00
IUUC-Oga-088109	Otolemur garnettii	70.28	0.00e+00	712.00
IUUC-Oar-090310	Ovis aries	58.63	1.00e-164	572.00
IUUC-Ptr-090643	Pan troglodytes	70.28	0.00e+00	709.00
IUUC-Pan-091933	Papio anubis	69.79	0.00e+00	704.00
IUUC-Psi-093681	Pelodiscus sinensis	70.58	0.00e+00	710.00
IUUC-Pfo-096148	Poecilia formosa	55.94	6.00e-172	596.00
IUUC-Pab-098631	Pongo abelii	70.28	0.00e+00	709.00
IUUC-Pca-100582	Procavia capensis	61.09	2.00e-80	292.00
IUUC-Pva-102396	Pteropus vampyrus	59.09	7.00e-159	553.00
IUUC-Rno-106120	Rattus norvegicus	68.06	0.00e+00	660.00
IUUC-Sha-106493	Sarcophilus harrisii	72.27	0.00e+00	724.00
IUUC-Sar-113570	Sorex araneus	86.74	1.00e-96	345.00
IUUC-Ssc-115843	Sus scrofa	65.65	0.00e+00	687.00
IUUC-Tru-117853	Takifugu rubripes	57.04	2.00e-169	588.00
IUUC-Tni-120256	Tetraodon nigroviridis	60.27	4.00e-178	617.00
IUUC-Tbe-127943	Tupaia belangeri	61.49	9.00e-94	335.00
IUUC-Ttr-129246	Tursiops truncatus	67.51	0.00e+00	670.00
IUUC-Xtr-132279	Xenopus tropicalis	59.09	2.00e-157	548.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence