iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132464

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-specific peptidase 12

Genbank Nucleotide ID

AAMC01116171

Gene Name

usp12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000009799.3	ENSXETT00000021585.3	ENSXETP00000021585.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.70e-97	325.7	23	353

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +Gl N+gNtCY+NSvLQ+L++++++re +l  +k++      + +k++ll++l++lf+++   k+k +++ p+++++ l+ke+e f++y
   Q: 23   FGLVNFGNTCYCNSVLQALYFCRPFREKVLA-YKSQ------PRKKENLLTCLADLFHSIAtqKKKVGVIPPKKFITRLRKENELFDNY 104
           6******************************.4444......456789************976777779******************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +qqDa+Efl++ll+++ + l++   ++k+e+++ +  + + ++e+++ +  +++++++Fqg+l+++++cl+c+++ss++e+fldls++v
   Q: 105  MQQDAHEFLNYLLNTIADILQE---ERKQEKQNGRIPNGNIDNENNNSTPDPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDV 190
           ********************33...333334334444445557778888889************************************* PP
   S: 177  pgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspf 264
           ++++     s+++cL + f+++e+l++e kyyce+c++kqea k++k+kklP +L lhLkRf++  + ++ +k++ +v fpleL l  f
   Q: 191  EQNT-----SITHCLsRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRL--F 272
           ****.....9*****889***************************************************************66665..7 PP
   S: 265  ctspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg.........staYvlfYkr 337
           +ts +   + ++ Y+L+avvvH G +++ GHY+a+vk+ ++ WllfdD+ V++++ + ++e+ g         +++Y+lfY++
   Q: 273  NTSGDA-TNPDRMYDLVAVVVHCGsGPNRGHYIAIVKS-HDFWLLFDDDIVEKIDAQAIEEFYGltsdisknsESGYILFYQS 353
           777444.4469***************************.555*******************999*****************97 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

GANASALEKE IGPEQFPVNE HYFGLVNFGN TCYCNSVLQA LYFCRPFREK VLAYKSQPRK 60
KENLLTCLAD LFHSIATQKK KVGVIPPKKF ITRLRKENEL FDNYMQQDAH EFLNYLLNTI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGCCAATG CCTCGGCTTT AGAGAAAGAG ATTGGGCCGG AACAATTTCC AGTAAATGAA 60
CACTATTTTG GTTTAGTAAA TGTAAGTATA TGCCACTGCA TTTGTTTTAA TTGGGAATCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001964	Ailuropoda melanoleuca	99.15	0.00e+00	713.00
IUUC-Apl-003411	Anas platyrhynchos	98.59	0.00e+00	705.00
IUUC-Aca-005212	Anolis carolinensis	97.75	0.00e+00	705.00
IUUC-Afl-008602	Aspergillus flavus	50.00	1.00e-77	283.00
IUUC-Afu-008816	Aspergillus fumigatus	49.33	7.00e-76	278.00
IUUC-Aor-009901	Aspergillus oryzae	50.00	1.00e-77	284.00
IUUC-Ate-010431	Aspergillus terreus	50.00	4.00e-76	279.00
IUUC-Bci-013837	Botrytis cinerea	40.74	3.00e-72	266.00
IUUC-Cja-018831	Callithrix jacchus	99.15	0.00e+00	711.00
IUUC-Cfa-020534	Canis familiaris	98.87	0.00e+00	712.00
IUUC-Cpo-021703	Cavia porcellus	99.15	0.00e+00	711.00
IUUC-Cre-022711	Chlamydomonas reinhardtii	53.93	1.00e-96	346.00
IUUC-Cho-024902	Choloepus hoffmanni	82.54	6.00e-164	569.00
IUUC-Cgl-026611	Colletotrichum gloeosporioides	42.76	2.00e-73	270.00
IUUC-Dno-029460	Dasypus novemcinctus	98.87	0.00e+00	711.00
IUUC-Dor-030972	Dipodomys ordii	98.83	4.00e-145	506.00
IUUC-Ete-033125	Echinops telfairi	77.63	3.00e-126	444.00
IUUC-Eca-033439	Equus caballus	99.15	0.00e+00	712.00
IUUC-Fca-035524	Felis catus	98.59	0.00e+00	710.00
IUUC-Fal-036833	Ficedula albicollis	97.46	0.00e+00	704.00
IUUC-Fso-038299	Fusarium solani	37.50	1.00e-71	264.00
IUUC-Hsa-045700	Homo sapiens	99.15	0.00e+00	711.00
IUUC-Itr-049082	Ictidomys tridecemlineatus	99.15	0.00e+00	713.00
IUUC-Lch-050435	Latimeria chalumnae	97.46	0.00e+00	707.00
IUUC-Laf-053887	Loxodonta africana	99.15	0.00e+00	713.00
IUUC-Mcc-055701	Macaca mulatta	99.15	0.00e+00	711.00
IUUC-Mga-059195	Meleagris gallopavo	98.59	0.00e+00	703.00
IUUC-Mmr-060751	Microcebus murinus	99.15	0.00e+00	713.00
IUUC-Mdo-062735	Monodelphis domestica	97.46	0.00e+00	701.00
IUUC-Mmu-063263	Mus musculus	98.03	0.00e+00	708.00
IUUC-Mlu-068128	Myotis lucifugus	99.15	0.00e+00	712.00
IUUC-Ncr-068699	Neurospora crassa	44.48	9.00e-74	271.00
IUUC-Nle-069767	Nomascus leucogenys	99.15	0.00e+00	711.00
IUUC-Oan-073372	Ornithorhynchus anatinus	97.75	0.00e+00	706.00
IUUC-Ocu-074322	Oryctolagus cuniculus	98.87	0.00e+00	710.00
IUUC-Obr-076088	Oryza brachyantha	57.07	1.00e-115	409.00
IUUC-Oga-088298	Otolemur garnettii	99.15	0.00e+00	712.00
IUUC-Oar-090269	Ovis aries	98.31	0.00e+00	706.00
IUUC-Ptr-090467	Pan troglodytes	99.15	0.00e+00	711.00
IUUC-Pan-092437	Papio anubis	98.88	0.00e+00	707.00
IUUC-Psi-092993	Pelodiscus sinensis	98.87	0.00e+00	711.00
IUUC-Pab-097797	Pongo abelii	99.15	0.00e+00	711.00
IUUC-Pca-100835	Procavia capensis	88.41	9.00e-167	578.00
IUUC-Rno-106060	Rattus norvegicus	97.46	0.00e+00	706.00
IUUC-Sha-107087	Sarcophilus harrisii	99.15	0.00e+00	713.00
IUUC-Sja-107684	Schizosaccharomyces japonicus	43.29	2.00e-66	246.00
IUUC-Spo-108095	Schizosaccharomyces pombe	46.23	3.00e-74	272.00
IUUC-Sly-111210	Solanum lycopersicum	58.90	3.00e-120	424.00
IUUC-Sar-113216	Sorex araneus	98.59	0.00e+00	703.00
IUUC-Sre-115197	Sporisorium reilianum	50.00	2.00e-78	287.00
IUUC-Ssc-116321	Sus scrofa	98.31	0.00e+00	708.00
IUUC-Tgu-117482	Taeniopygia guttata	95.77	0.00e+00	692.00
IUUC-Tsy-119520	Tarsius syrichta	88.28	7.00e-124	436.00
IUUC-Tre-122226	Trichoderma reesei	44.88	1.00e-73	271.00
IUUC-Tvi-122330	Trichoderma virens	45.07	2.00e-73	270.00
IUUC-Tme-126890	Tuber melanosporum	46.61	1.00e-88	320.00
IUUC-Tbe-127783	Tupaia belangeri	98.03	0.00e+00	693.00
IUUC-Ttr-129083	Tursiops truncatus	98.87	0.00e+00	712.00
IUUC-Vda-129736	Verticillium dahliae	37.46	2.00e-56	214.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence