iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-120807

UUCD1 version

UUC-TeN-00749

Ensembl Protein ID

ENSTNIP00000000007.1

UniProt Accession

H3BVJ5; H3BVJ5_TETNG

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000011048.1	ENSTNIT00000001665.1	ENSTNIP00000000007.1
ENSTNIG00000011048.1	ENSTNIT00000014179.1	ENSTNIP00000013984.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.40e-94	317.4	732	1056

Active Site

Position(s)	Description	Evidence
1025	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlld 89
            dlkk l+v f gEe++d+gGvt+ef+ ll+kel +p +g+f+++++++  ++ ++        + k+F+++G+++g+a++++ ++d
   Q: 732  VDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELMDPIYGMFTFHNESNLLWFSDKCFV-----EQKWFHLIGIICGLAIYNSTVVD 813
           589************************************************99888664.....579******************** PP
   S: 90   lplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvkl 176
           l+++ ++yk+ll+++ +ledl+e+ p+ ++sl+++++++++d+ee+ + l+f ++ e++g ++++eL+pgGe+i+V ++N++e+v++
   Q: 814  LHFPLALYKKLLDVSPTLEDLKELSPTEARSLQQLLDYENEDVEET-FLLSFAITRENYGIIEVKELVPGGESISVDKNNRKEFVEA 899
           **************************************99999997.**************************************** PP
   S: 177  vveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerka 263
           ++ y++ ++  eq+ af++Gf +v+  e+lslF++ el  ++ G++++++e ++k+t ykg++t+++p+++ Fwev++ef  e++k+
   Q: 900  YLRYIFSDSASEQYSAFSAGFLKVCGGEILSLFQPCELMAMVVGNSNYNWEVMEKNTVYKGEFTATHPTVRLFWEVFHEFPLEKKKQ 986
           *************************************************************************************** PP
   S: 264  fLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           fL F+Tgs+r+P+ G+++l+   +vi+   a+++ lP ++TC+n+L++P+Y++keil+ +L+ A+e+ +gF+l
   Q: 987  FLLFLTGSDRIPIHGMESLR---IVIQStMAEERYLPVAHTCYNLLDMPRYQTKEILRCRLTQAVEQYEGFSL 1056
           ********************...8888867888**************************************97 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MLCWGKAKDG QLGIEVERNS MFEPRNCNVF SGRGLKEAVC GGQHSVFLLH DGSVYTCGSN 60
GCGQLGHNKP GTSPELVGAL DTQRITLVSC GQAHSMAVNE QGQVFAWGAG DGGQLGLGTT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGTGTT GGGGGAAAGC AAAAGATGGG CAGCTGGGCA TTGAAGTGGA GAGGAATTCG 60
ATGTTTGAGC CCAGAAACTG TAATGTGTTT AGTGGCAGGG GCCTGAAAGA AGCAGTCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens

PROSITE

PS50237--HECT
PS00626--RCC1_2
PS50012--RCC1_3

Pfam

PF00632--HECT
PF00415--RCC1

PRINTS

PR00633--RCCNDNSATION

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001673	Ailuropoda melanoleuca	63.80	0.00e+00	1320.00
IUUC-Apl-003535	Anas platyrhynchos	65.09	0.00e+00	1337.00
IUUC-Aca-005223	Anolis carolinensis	64.21	0.00e+00	1329.00
IUUC-Ame-010816	Astyanax mexicanus	75.95	0.00e+00	1336.00
IUUC-Bta-013373	Bos taurus	63.71	0.00e+00	1326.00
IUUC-Cja-019609	Callithrix jacchus	63.83	0.00e+00	1320.00
IUUC-Cfa-021071	Canis familiaris	63.61	0.00e+00	1316.00
IUUC-Cpo-021548	Cavia porcellus	63.55	0.00e+00	1313.00
IUUC-Csa-023987	Chlorocebus sabaeus	63.89	0.00e+00	1320.00
IUUC-Cho-024325	Choloepus hoffmanni	70.99	0.00e+00	856.00
IUUC-Dre-027472	Danio rerio	77.53	0.00e+00	1630.00
IUUC-Dno-029241	Dasypus novemcinctus	63.11	0.00e+00	1302.00
IUUC-Dor-030672	Dipodomys ordii	53.28	8.00e-179	620.00
IUUC-Ete-032642	Echinops telfairi	62.38	0.00e+00	1239.00
IUUC-Eca-033646	Equus caballus	63.52	0.00e+00	1312.00
IUUC-Eeu-035098	Erinaceus europaeus	60.81	0.00e+00	806.00
IUUC-Fal-036952	Ficedula albicollis	65.44	0.00e+00	1339.00
IUUC-Gmo-039297	Gadus morhua	75.73	0.00e+00	1567.00
IUUC-Gga-040591	Gallus gallus	64.78	0.00e+00	1329.00
IUUC-Gac-041741	Gasterosteus aculeatus	85.08	0.00e+00	1831.00
IUUC-Ggo-044769	Gorilla gorilla	63.83	0.00e+00	1318.00
IUUC-Hsa-046066	Homo sapiens	63.80	0.00e+00	1320.00
IUUC-Itr-048311	Ictidomys tridecemlineatus	63.55	0.00e+00	1315.00
IUUC-Lch-050301	Latimeria chalumnae	65.12	0.00e+00	1401.00
IUUC-Loc-052803	Lepisosteus oculatus	74.38	0.00e+00	1603.00
IUUC-Laf-053364	Loxodonta africana	64.27	0.00e+00	1326.00
IUUC-Mcc-054930	Macaca mulatta	63.89	0.00e+00	1320.00
IUUC-Meu-056274	Macropus eugenii	51.64	3.00e-150	526.00
IUUC-Mga-059563	Meleagris gallopavo	65.09	0.00e+00	1338.00
IUUC-Mmr-060792	Microcebus murinus	62.85	0.00e+00	1292.00
IUUC-Mdo-062195	Monodelphis domestica	64.25	0.00e+00	1326.00
IUUC-Mmu-063855	Mus musculus	63.27	0.00e+00	1312.00
IUUC-Mpu-066308	Mustela putorius furo	63.71	0.00e+00	1320.00
IUUC-Mlu-066927	Myotis lucifugus	63.71	0.00e+00	1318.00
IUUC-Nle-070090	Nomascus leucogenys	63.80	0.00e+00	1319.00
IUUC-Opr-070891	Ochotona princeps	60.58	0.00e+00	1053.00
IUUC-Ont-072201	Oreochromis niloticus	84.01	0.00e+00	1793.00
IUUC-Ocu-074770	Oryctolagus cuniculus	63.77	0.00e+00	1318.00
IUUC-Ola-086550	Oryzias latipes	82.70	0.00e+00	1797.00
IUUC-Oga-088831	Otolemur garnettii	63.68	0.00e+00	1310.00
IUUC-Oar-090449	Ovis aries	63.89	0.00e+00	1321.00
IUUC-Pan-092135	Papio anubis	63.83	0.00e+00	1320.00
IUUC-Psi-093832	Pelodiscus sinensis	63.74	0.00e+00	1343.00
IUUC-Pfo-097268	Poecilia formosa	84.80	0.00e+00	1825.00
IUUC-Pab-098249	Pongo abelii	63.71	0.00e+00	1320.00
IUUC-Pca-100855	Procavia capensis	57.22	0.00e+00	837.00
IUUC-Pva-102506	Pteropus vampyrus	58.26	0.00e+00	1136.00
IUUC-Rno-105242	Rattus norvegicus	63.52	0.00e+00	1356.00
IUUC-Sar-113612	Sorex araneus	70.81	6.00e-155	541.00
IUUC-Ssc-115473	Sus scrofa	63.80	0.00e+00	1320.00
IUUC-Tgu-116974	Taeniopygia guttata	65.38	0.00e+00	1320.00
IUUC-Tru-118077	Takifugu rubripes	91.51	0.00e+00	1950.00
IUUC-Tsy-119619	Tarsius syrichta	54.44	0.00e+00	1120.00
IUUC-Tbe-127640	Tupaia belangeri	61.81	0.00e+00	1243.00
IUUC-Ttr-129172	Tursiops truncatus	63.52	0.00e+00	1310.00
IUUC-Xtr-132194	Xenopus tropicalis	56.87	0.00e+00	1073.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence