iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074066

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02040303

Gene Name

USP11

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000008403.3	ENSOCUT00000008412.3	ENSOCUP00000007268.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.00e-114	381.0	297	918

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS+LQcLsn+p+l+e++l+ ++ e+ln +np ++kgel++++++l+++ w+++++++ p+ ++++++++a++f gy+
   Q: 297  CGLTNLGNTCFMNSALQCLSNVPQLTEYFLNnRYLEELNFRNPLGMKGELAEAYADLVKQAWSGHHRSIVPHVFKNKVGHFASQFLGYQ 385
           7******************************99******************************************************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde...aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           q+D+qE+l+flld+l+e+l++ k+k++ e+++++ +  ++    a++++k++n+s+i+d+F+g +ks+++c++c+nvs++++pf++ls+
   Q: 386  QHDSQELLSFLLDGLHEDLNRVKKKEYVELCDAAGRPDQEVaqeAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSV 474
           *****************************998874333322555********************************************* PP
   S: 175  pvpgkeetkke.............................................................................. 185
           p+p ++++ +e                                                                              
   Q: 475  PLPVSHKRVMEvffipmdprrkpeqhrvvvpkkgnisdlcvalskhtgiapdrmmvadvfshrfyklyqledslstildrddifvyevt 563
           ******99999****************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 564  grieaiegsredivvpvymrertpardynnsyyglmlfghpllvsvprdrfsweglynilmyrlsryvtkpssddeddgdekgdddedk 652
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 653  dampgpstrgslrepepeqagpssgvtrrcpflldnclrssqwpprrrrkqlftlqtvnsngtsdrttspedvqtqpyiaidwepemkr 741
           ***************************************************************************************** PP
   S: 186  ..........................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrek 248
                                     +lq+c+e ft+ e+le+en +yc++ck++q a+kkl+l+ lPe+Li+hLkRfs+s+   srek
   Q: 742  ryydeveaegyvkhdcvgyvlkkapvQLQECIELFTTMETLEKENPWYCPSCKRHQLATKKLDLWMLPEILIIHLKRFSYSK--FSREK 828
           ******************************************************************************9977..799** PP
   S: 249  inkkvefple.Ldlspfctspeekqke.kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlf 334
           +++ v+fp++ Ld s f+++p+++++   +kY+Liav +H+G+++ GHY++++ n ++g+W +fdDs+V++v+e+++++   + aYvlf
   Q: 829  LDTLVQFPIRdLDFSDFVIKPQNESAPeLYKYDLIAVSNHYGGMRDGHYTTFACNkDSGQWHYFDDSSVSPVNENQIES---KAAYVLF 914
           *****************9999887754489*********************988834566*******************...******* PP
   S: 335  Ykrr 338
           Y+r+
   Q: 915  YQRQ 918
           **96 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MAVVPWLFGG LCFRFRYQNP EVAIEGLPIS SCVGRRGRTA MAAVAADRAA AAAAARQPRR 60
EAVPGLDSQR HQIENGENGR ERPLRAGESW FLVERDWYKQ WELYVQEGNQ DSCTFPGCIN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGTAG TCCCCTGGTT GTTCGGGGGG CTCTGCTTCC GTTTCCGGTA CCAGAATCCG 60
GAAGTGGCAA TCGAGGGTCT TCCTATCTCC AGTTGCGTCG GCAGAGAGAG GACGAACGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001760	Ailuropoda melanoleuca	81.73	0.00e+00	1489.00
IUUC-Atr-002675	Amborella trichopoda	37.84	1.00e-103	370.00
IUUC-Aca-004532	Anolis carolinensis	64.97	0.00e+00	1140.00
IUUC-Aly-006044	Arabidopsis lyrata	36.11	5.00e-139	488.00
IUUC-Ago-007911	Ashbya gossypii	37.56	2.00e-63	237.00
IUUC-Afu-008878	Aspergillus fumigatus	33.40	1.00e-55	212.00
IUUC-Ani-009479	Aspergillus nidulans	42.35	3.00e-52	201.00
IUUC-Ang-009562	Aspergillus niger	33.94	2.00e-55	212.00
IUUC-Ate-010323	Aspergillus terreus	35.25	3.00e-56	214.00
IUUC-Bta-013284	Bos taurus	82.77	0.00e+00	1464.00
IUUC-Bdi-014523	Brachypodium distachyon	33.55	1.00e-122	434.00
IUUC-Cel-018257	Caenorhabditis elegans	33.14	5.00e-96	345.00
IUUC-Cja-019746	Callithrix jacchus	89.33	0.00e+00	1565.00
IUUC-Cfa-020134	Canis familiaris	81.95	0.00e+00	1537.00
IUUC-Cpo-022535	Cavia porcellus	82.54	0.00e+00	1533.00
IUUC-Csa-023828	Chlorocebus sabaeus	87.93	0.00e+00	1647.00
IUUC-Dre-027398	Danio rerio	60.35	0.00e+00	723.00
IUUC-Dno-028853	Dasypus novemcinctus	81.52	0.00e+00	1283.00
IUUC-Dor-030384	Dipodomys ordii	83.33	0.00e+00	1580.00
IUUC-Eca-033271	Equus caballus	84.45	0.00e+00	1486.00
IUUC-Fca-036012	Felis catus	82.00	0.00e+00	1503.00
IUUC-Fox-037986	Fusarium oxysporum	43.75	5.00e-62	233.00
IUUC-Fso-038291	Fusarium solani	44.12	2.00e-63	238.00
IUUC-Gmo-038697	Gadus morhua	53.33	3.00e-178	619.00
IUUC-Gac-042574	Gasterosteus aculeatus	54.19	0.00e+00	887.00
IUUC-Hsa-046551	Homo sapiens	87.93	0.00e+00	1646.00
IUUC-Itr-048915	Ictidomys tridecemlineatus	86.07	0.00e+00	1596.00
IUUC-Kpa-049332	Komagataella pastoris	33.33	1.00e-73	271.00
IUUC-Laf-054561	Loxodonta africana	78.59	0.00e+00	1506.00
IUUC-Mcc-054881	Macaca mulatta	87.71	0.00e+00	1645.00
IUUC-Meu-056749	Macropus eugenii	77.09	0.00e+00	875.00
IUUC-Mla-058848	Melampsora laricipopulina	42.98	4.00e-71	263.00
IUUC-Mvi-060324	Microbotryum violaceum	31.78	4.00e-80	293.00
IUUC-Mmr-061400	Microcebus murinus	90.64	0.00e+00	1623.00
IUUC-Mmu-063241	Mus musculus	82.57	0.00e+00	1499.00
IUUC-Mpu-066507	Mustela putorius furo	82.25	0.00e+00	1515.00
IUUC-Mlu-066961	Myotis lucifugus	76.12	0.00e+00	1362.00
IUUC-Nfi-068330	Neosartorya fischeri	35.28	3.00e-55	211.00
IUUC-Nle-069284	Nomascus leucogenys	90.02	0.00e+00	1609.00
IUUC-Ont-071847	Oreochromis niloticus	57.22	0.00e+00	968.00
IUUC-Oan-073387	Ornithorhynchus anatinus	69.21	0.00e+00	1201.00
IUUC-Olu-087717	Ostreococcus lucimarinus	36.46	5.00e-112	398.00
IUUC-Oga-088424	Otolemur garnettii	90.01	0.00e+00	1610.00
IUUC-Oar-089732	Ovis aries	77.81	0.00e+00	1468.00
IUUC-Pan-092292	Papio anubis	86.49	0.00e+00	1648.00
IUUC-Pab-098779	Pongo abelii	81.83	0.00e+00	1387.00
IUUC-Pca-100851	Procavia capensis	79.82	0.00e+00	926.00
IUUC-Pva-103244	Pteropus vampyrus	80.15	0.00e+00	1462.00
IUUC-Ptt-103847	Puccinia triticina	36.99	2.00e-66	248.00
IUUC-Rno-105100	Rattus norvegicus	82.45	0.00e+00	1495.00
IUUC-Sha-107502	Sarcophilus harrisii	75.40	0.00e+00	863.00
IUUC-Sja-107752	Schizosaccharomyces japonicus	35.86	5.00e-82	299.00
IUUC-Spo-108291	Schizosaccharomyces pombe	33.61	5.00e-78	286.00
IUUC-Ssc-116345	Sus scrofa	82.21	0.00e+00	1519.00
IUUC-Tru-117788	Takifugu rubripes	55.45	0.00e+00	917.00
IUUC-Tsy-119414	Tarsius syrichta	80.81	0.00e+00	1181.00
IUUC-Tni-120107	Tetraodon nigroviridis	50.69	1.00e-159	557.00
IUUC-Tca-121001	Theobroma cacao	34.03	8.00e-136	478.00
IUUC-Tre-121888	Trichoderma reesei	44.49	5.00e-64	240.00
IUUC-Tvi-122422	Trichoderma virens	42.28	1.00e-58	222.00
IUUC-Tae-125515	Triticum aestivum	33.51	1.00e-119	424.00
IUUC-Tme-127062	Tuber melanosporum	33.75	2.00e-77	284.00
IUUC-Tbe-128081	Tupaia belangeri	88.66	0.00e+00	1003.00
IUUC-Ttr-128502	Tursiops truncatus	78.32	0.00e+00	1449.00
IUUC-Xma-133838	Xiphophorus maculatus	60.39	0.00e+00	739.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence