iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020718

Ensembl Protein ID

ENSCAFP00000015406.3

UniProt Accession

E2RIQ2; E2RIQ2_CANLF

Genbank Protein ID

ENSCAFP00000015406

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03011583

Gene Name

CTTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000010478.3	ENSCAFT00000016647.3	ENSCAFP00000015406.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.40e-12	47.7	489	538

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            +lydy+a+ dde ++   d+++ i  e  d gW++g    +g+ GlfP+n+ve
   Q: 489  VALYDYQAAGDDEISFDPDDIITNI--EMIDDGWWRG--LCKGRYGLFPANYVE 538
           69***********************..9*********..9************97 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MWKASAGHAV SITQDDGGAD DWETDPDFVN DVSEKEQRWG AKTVTGSGHQ EHINIHKLRE 60
NVFQEHQTLK EKELETGPKA SHGYGGKFGV EQDRMDKSAV GHEYQSKLSK HCSQVDSVRG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGGAAGG CTTCGGCAGG CCATGCTGTG TCCATCACCC AGGACGACGG CGGCGCCGAT 60
GACTGGGAGA CTGACCCTGA CTTTGTGGTA CGAGTCACCA GCCCACCCTT GCTGTACTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015503--Cortactin
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005884--C:actin filament
GO:0030863--C:cortical cytoskeleton
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0030027--C:lamellipodium
GO:1990023--C:mitotic spindle midzone
GO:0002102--C:podosome
GO:0001726--C:ruffle
GO:0008076--C:voltage-gated potassium channel complex
GO:0030041--P:actin filament polymerization
GO:0097062--P:dendritic spine maintenance
GO:0006886--P:intracellular protein transport
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0030838--P:positive regulation of actin filament polymerization
GO:0045987--P:positive regulation of smooth muscle contraction
GO:1903146--P:regulation of mitophagy
GO:0006930--P:substrate-dependent cell migration, cell extension

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002064	Ailuropoda melanoleuca	96.67	0.00e+00	969.00
IUUC-Apl-003745	Anas platyrhynchos	82.70	0.00e+00	778.00
IUUC-Aca-004438	Anolis carolinensis	79.64	0.00e+00	858.00
IUUC-Ame-011170	Astyanax mexicanus	41.87	2.00e-112	399.00
IUUC-Bgr-012041	Blumeria graminis	58.93	1.00e-15	78.60
IUUC-Bta-013563	Bos taurus	88.64	0.00e+00	876.00
IUUC-Cpo-022303	Cavia porcellus	87.30	0.00e+00	976.00
IUUC-Csa-023431	Chlorocebus sabaeus	89.47	0.00e+00	931.00
IUUC-Cin-025677	Ciona intestinalis	62.24	2.00e-119	422.00
IUUC-Csv-026140	Ciona savignyi	64.33	7.00e-109	387.00
IUUC-Dre-028012	Danio rerio	64.07	3.00e-177	614.00
IUUC-Dno-029332	Dasypus novemcinctus	80.25	0.00e+00	765.00
IUUC-Dme-031931	Drosophila melanogaster	62.17	2.00e-73	270.00
IUUC-Eca-033801	Equus caballus	91.99	0.00e+00	930.00
IUUC-Fca-035633	Felis catus	93.02	0.00e+00	788.00
IUUC-Fal-036775	Ficedula albicollis	82.52	0.00e+00	795.00
IUUC-Fox-037778	Fusarium oxysporum	61.82	4.00e-14	73.90
IUUC-Gmo-038507	Gadus morhua	58.23	8.00e-21	95.10
IUUC-Gga-040568	Gallus gallus	82.70	0.00e+00	806.00
IUUC-Gac-042253	Gasterosteus aculeatus	55.98	3.00e-114	405.00
IUUC-Hsa-046818	Homo sapiens	90.38	0.00e+00	937.00
IUUC-Itr-048833	Ictidomys tridecemlineatus	86.05	0.00e+00	857.00
IUUC-Lch-050199	Latimeria chalumnae	70.83	9.00e-146	510.00
IUUC-Loc-052855	Lepisosteus oculatus	75.35	7.00e-154	537.00
IUUC-Lma-053035	Leptosphaeria maculans	59.18	3.00e-12	67.40
IUUC-Laf-053866	Loxodonta africana	87.34	0.00e+00	958.00
IUUC-Mcc-055515	Macaca mulatta	89.11	0.00e+00	904.00
IUUC-Mga-059791	Meleagris gallopavo	83.27	0.00e+00	808.00
IUUC-Mmr-061147	Microcebus murinus	90.24	0.00e+00	871.00
IUUC-Mdo-062660	Monodelphis domestica	61.32	1.00e-174	607.00
IUUC-Mmu-064023	Mus musculus	89.03	0.00e+00	919.00
IUUC-Mpu-065867	Mustela putorius furo	85.95	0.00e+00	835.00
IUUC-Mlu-067704	Myotis lucifugus	83.09	0.00e+00	774.00
IUUC-Ont-071873	Oreochromis niloticus	80.67	2.00e-168	585.00
IUUC-Oan-073528	Ornithorhynchus anatinus	81.39	3.00e-163	567.00
IUUC-Oga-088028	Otolemur garnettii	89.29	0.00e+00	925.00
IUUC-Oar-090203	Ovis aries	88.05	0.00e+00	802.00
IUUC-Pan-092594	Papio anubis	85.14	0.00e+00	845.00
IUUC-Psi-093389	Pelodiscus sinensis	82.09	0.00e+00	811.00
IUUC-Pma-094161	Petromyzon marinus	46.30	2.00e-83	303.00
IUUC-Pfo-096269	Poecilia formosa	60.00	3.00e-107	382.00
IUUC-Pab-097913	Pongo abelii	82.03	0.00e+00	797.00
IUUC-Rno-105489	Rattus norvegicus	88.48	0.00e+00	876.00
IUUC-Sce-106228	Saccharomyces cerevisiae	50.00	8.00e-07	48.90
IUUC-Sha-107308	Sarcophilus harrisii	68.17	0.00e+00	666.00
IUUC-Sja-107956	Schizosaccharomyces japonicus	55.17	1.00e-14	75.10
IUUC-Tgu-117049	Taeniopygia guttata	76.09	0.00e+00	718.00
IUUC-Tru-118718	Takifugu rubripes	66.97	0.00e+00	642.00
IUUC-Tni-120535	Tetraodon nigroviridis	59.52	9.00e-173	599.00
IUUC-Tre-122167	Trichoderma reesei	59.18	1.00e-11	65.10
IUUC-Vda-129766	Verticillium dahliae	58.18	2.00e-13	70.90
IUUC-Xtr-131797	Xenopus tropicalis	65.62	0.00e+00	669.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence