iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000014296.3	ENSCJAT00000027830.2	ENSCJAP00000026334.2
ENSCJAG00000014296.3	ENSCJAT00000027826.2	ENSCJAP00000026330.2
ENSCJAG00000014296.3	ENSCJAT00000027806.2	ENSCJAP00000026311.2
ENSCJAG00000014296.3	ENSCJAT00000059136.1	ENSCJAP00000050788.1
ENSCJAG00000014296.3	ENSCJAT00000027809.2	ENSCJAP00000026315.2
ENSCJAG00000014296.3	ENSCJAT00000056698.1	ENSCJAP00000049010.1
ENSCJAG00000014296.3	ENSCJAT00000027802.2	ENSCJAP00000026307.2
ENSCJAG00000014296.3	ENSCJAT00000027828.2	ENSCJAP00000026332.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.10e-11	43.3	56	106

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqd.egWlkgvkelegkrGlfPen 57
            ++lyd  a++ deL+++kGd+++v+e+++q   gW+ +   l+g++G++P n
   Q: 56   AKALYDNVAESPDELSFRKGDIMTVLEQDTQGlDGWWLC--SLHGRQGIVPGN 106
           689***********************666654389****..9*********98 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MSARPFLSSA LLSLRALDFS GSGPQGTGQP QSCEHWAEGQ GGPPEPAGGG PDNVLAKALY 60
DNVAESPDEL SFRKGDIMTV LEQDTQGLDG WWLCSLHGRQ GIVPGNRLKI LVGMYDKKPA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCTGCCAGG AGTGGGTGAG AGAGGAGAAG CCGCCGCCTT CACAGACACC TGGTAGTGTT 60
AGGAGAGGGC ATGCAATACC CTGGTGAGGC TCCTTTGGCT GCCCCCAGGC CCACACCCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0732--Signal

Interpro

IPR028848--BCAR1
IPR021901--CAS_DUF3513
IPR014928--Serine_rich
IPR001452--SH3_domain
IPR013315--Spectrin_alpha_SH3
IPR015224--Talin_cent

PROSITE

PS50002--SH3

Pfam

PF12026--DUF3513
PF08824--Serine_rich
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN
PR01887--SPECTRNALPHA

SMART

SM00326--SH3

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005737--C:cytoplasm
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0001726--C:ruffle
GO:0004871--F:signal transducer activity
GO:0007015--P:actin filament organization
GO:0050853--P:B cell receptor signaling pathway
GO:0060326--P:cell chemotaxis
GO:0035729--P:cellular response to hepatocyte growth factor stimulus
GO:0007186--P:G-protein coupled receptor signaling pathway
GO:0048012--P:hepatocyte growth factor receptor signaling pathway
GO:0007229--P:integrin-mediated signaling pathway
GO:0048008--P:platelet-derived growth factor receptor signaling pathway
GO:0010595--P:positive regulation of endothelial cell migration
GO:0048010--P:vascular endothelial growth factor receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001208	Ailuropoda melanoleuca	89.89	0.00e+00	1198.00
IUUC-Apl-003391	Anas platyrhynchos	38.49	1.00e-139	490.00
IUUC-Aca-004548	Anolis carolinensis	37.68	3.00e-142	499.00
IUUC-Bta-013197	Bos taurus	82.93	0.00e+00	1171.00
IUUC-Cfa-020772	Canis familiaris	90.61	0.00e+00	1306.00
IUUC-Cpo-022455	Cavia porcellus	89.43	0.00e+00	1271.00
IUUC-Csa-023660	Chlorocebus sabaeus	95.40	0.00e+00	1401.00
IUUC-Cin-025595	Ciona intestinalis	28.62	1.00e-67	251.00
IUUC-Dre-028389	Danio rerio	53.83	0.00e+00	836.00
IUUC-Dno-028907	Dasypus novemcinctus	87.01	0.00e+00	1162.00
IUUC-Dor-030300	Dipodomys ordii	94.71	1.00e-164	573.00
IUUC-Dme-031580	Drosophila melanogaster	28.89	3.00e-41	163.00
IUUC-Ete-032641	Echinops telfairi	94.57	1.00e-130	460.00
IUUC-Eca-033297	Equus caballus	91.72	0.00e+00	1316.00
IUUC-Eeu-035356	Erinaceus europaeus	84.27	0.00e+00	904.00
IUUC-Fca-036302	Felis catus	90.69	0.00e+00	1221.00
IUUC-Fal-036729	Ficedula albicollis	64.03	0.00e+00	1044.00
IUUC-Gga-040285	Gallus gallus	62.59	0.00e+00	986.00
IUUC-Ggo-045534	Gorilla gorilla	93.82	0.00e+00	1407.00
IUUC-Hsa-046672	Homo sapiens	94.36	0.00e+00	1420.00
IUUC-Itr-048045	Ictidomys tridecemlineatus	91.84	0.00e+00	1294.00
IUUC-Lch-049837	Latimeria chalumnae	59.52	0.00e+00	906.00
IUUC-Loc-052010	Lepisosteus oculatus	55.00	0.00e+00	850.00
IUUC-Laf-053978	Loxodonta africana	90.59	0.00e+00	1229.00
IUUC-Mcc-055551	Macaca mulatta	92.41	0.00e+00	1406.00
IUUC-Meu-056006	Macropus eugenii	66.63	0.00e+00	939.00
IUUC-Mga-060136	Meleagris gallopavo	41.06	3.00e-154	538.00
IUUC-Mmr-061269	Microcebus murinus	90.67	0.00e+00	1337.00
IUUC-Mmu-063741	Mus musculus	90.57	0.00e+00	1321.00
IUUC-Mpu-066694	Mustela putorius furo	90.34	0.00e+00	1224.00
IUUC-Mlu-067377	Myotis lucifugus	89.20	0.00e+00	1239.00
IUUC-Nle-069243	Nomascus leucogenys	92.45	0.00e+00	724.00
IUUC-Opr-070611	Ochotona princeps	84.85	0.00e+00	1184.00
IUUC-Ont-071724	Oreochromis niloticus	51.82	0.00e+00	762.00
IUUC-Oan-073477	Ornithorhynchus anatinus	51.42	1.00e-46	178.00
IUUC-Ocu-074436	Oryctolagus cuniculus	92.69	0.00e+00	1056.00
IUUC-Ola-086487	Oryzias latipes	49.29	0.00e+00	717.00
IUUC-Oga-088966	Otolemur garnettii	91.78	0.00e+00	1391.00
IUUC-Oar-089394	Ovis aries	78.69	2.00e-129	456.00
IUUC-Ptr-090896	Pan troglodytes	94.47	0.00e+00	1453.00
IUUC-Pan-092021	Papio anubis	94.94	0.00e+00	1368.00
IUUC-Pab-098732	Pongo abelii	91.15	0.00e+00	1265.00
IUUC-Pca-100841	Procavia capensis	89.49	1.00e-178	620.00
IUUC-Pva-102291	Pteropus vampyrus	85.07	0.00e+00	875.00
IUUC-Rno-105602	Rattus norvegicus	90.80	0.00e+00	1322.00
IUUC-Sha-106605	Sarcophilus harrisii	63.70	6.00e-90	325.00
IUUC-Spo-108375	Schizosaccharomyces pombe	41.82	8.00e-08	53.50
IUUC-Ssc-116113	Sus scrofa	88.53	0.00e+00	1206.00
IUUC-Tgu-117420	Taeniopygia guttata	37.94	3.00e-144	505.00
IUUC-Tru-118044	Takifugu rubripes	46.43	5.00e-31	129.00
IUUC-Ttr-128533	Tursiops truncatus	88.28	0.00e+00	1201.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence