iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-012680

Ensembl Protein ID

ENSBTAP00000013682.4

UniProt Accession

Q2KJB5; NOSTN_BOVIN

Genbank Protein ID

AAI05427.1

Protein Name

Nostrin; Nitric oxide synthase trafficker; eNOS trafficking inducer

Genbank Nucleotide ID

BC105426

Gene Name

NOSTRIN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000010362.4	ENSBTAT00000013682.4	ENSBTAP00000013682.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.00e-17	62.1	441	494

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           ++++ly+++a +ddeL l+kGd+v++  ++++degW+ g   l+gk+G fP+ +ve+l
   Q: 441  LCKALYPFQARQDDELDLEKGDIVTI--HKKKDEGWWFG--SLKGKKGHFPAAYVEEL 494
           69************************..59*********..9*************997 PP

Organism

Bos taurus

Functional Description
(View)

Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane.

Protein Sequence
(Fasta)

MRDPLTDCSY NKVYKNLKEF SQNGEDFCKQ ITSILQQRAN LEINYAKGLQ KLATKLSKTL 60
QSAKKNCLVS AWAWVSEGMK SAGDLHQKLG KAIELEAIKP AHQVLSAHEK KRKSLENEVE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCATCCTGA ATGCCGGAGT GTAGGTACAA GGACTGAAGC AAACAGCATT TCACCATGAG 60
GGACCCACTG ACAGACTGTT CGGTGAGTAG CTCCGTGTAA TTTGCGTGCC TGCGTGTGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-1003--Cell membrane
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0206--Cytoskeleton
KW-0254--Endocytosis
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR011072--HR1_rho-bd
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0031410--C:cytoplasmic vesicle
GO:0005856--C:cytoskeleton
GO:0005886--C:plasma membrane
GO:0006897--P:endocytosis
GO:0007165--P:signal transduction

KEGG

bta:521834

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001403	Ailuropoda melanoleuca	74.15	0.00e+00	694.00
IUUC-Aca-005138	Anolis carolinensis	52.34	2.00e-137	482.00
IUUC-Aly-005591	Arabidopsis lyrata	39.47	5.00e-10	58.50
IUUC-Cja-019985	Callithrix jacchus	81.62	0.00e+00	768.00
IUUC-Cfa-020888	Canis familiaris	71.94	0.00e+00	683.00
IUUC-Cpo-021852	Cavia porcellus	81.01	0.00e+00	721.00
IUUC-Csa-023196	Chlorocebus sabaeus	82.41	0.00e+00	753.00
IUUC-Cin-025272	Ciona intestinalis	25.00	2.00e-27	117.00
IUUC-Dre-027969	Danio rerio	43.95	6.00e-116	410.00
IUUC-Dno-029703	Dasypus novemcinctus	78.85	0.00e+00	713.00
IUUC-Dor-030928	Dipodomys ordii	79.84	0.00e+00	712.00
IUUC-Dme-032164	Drosophila melanogaster	25.74	7.00e-22	100.00
IUUC-Ete-033034	Echinops telfairi	62.13	5.00e-144	504.00
IUUC-Eca-034165	Equus caballus	88.74	0.00e+00	875.00
IUUC-Eeu-034697	Erinaceus europaeus	83.86	0.00e+00	817.00
IUUC-Fca-035811	Felis catus	84.66	0.00e+00	782.00
IUUC-Gac-041751	Gasterosteus aculeatus	45.77	3.00e-119	422.00
IUUC-Hsa-046868	Homo sapiens	71.94	0.00e+00	688.00
IUUC-Itr-049056	Ictidomys tridecemlineatus	82.02	0.00e+00	783.00
IUUC-Lch-050314	Latimeria chalumnae	45.32	7.00e-119	421.00
IUUC-Loc-051803	Lepisosteus oculatus	48.52	2.00e-131	462.00
IUUC-Laf-053672	Loxodonta africana	80.40	0.00e+00	745.00
IUUC-Mcc-054984	Macaca mulatta	74.59	0.00e+00	719.00
IUUC-Mvi-060364	Microbotryum violaceum	41.07	2.00e-10	59.30
IUUC-Mmr-061250	Microcebus murinus	83.20	0.00e+00	777.00
IUUC-Mdo-062278	Monodelphis domestica	74.21	0.00e+00	698.00
IUUC-Mmu-063360	Mus musculus	78.85	0.00e+00	702.00
IUUC-Mpu-065954	Mustela putorius furo	85.69	0.00e+00	763.00
IUUC-Mlu-066993	Myotis lucifugus	82.13	0.00e+00	750.00
IUUC-Nle-069744	Nomascus leucogenys	67.98	3.00e-180	624.00
IUUC-Opr-070442	Ochotona princeps	69.31	3.00e-180	624.00
IUUC-Ont-072001	Oreochromis niloticus	43.22	3.00e-121	428.00
IUUC-Oan-072971	Ornithorhynchus anatinus	66.34	3.00e-170	591.00
IUUC-Ocu-074140	Oryctolagus cuniculus	80.59	0.00e+00	729.00
IUUC-Ogl-077392	Oryza glaberrima	23.33	4.20e-01	30.40
IUUC-Osa-085362	Oryza sativa	23.33	4.20e-01	30.40
IUUC-Ola-086827	Oryzias latipes	45.04	6.00e-113	400.00
IUUC-Oga-088144	Otolemur garnettii	83.40	0.00e+00	776.00
IUUC-Oar-090280	Ovis aries	97.63	0.00e+00	900.00
IUUC-Ptr-091508	Pan troglodytes	82.02	0.00e+00	743.00
IUUC-Pan-092649	Papio anubis	81.31	0.00e+00	708.00
IUUC-Pfo-097405	Poecilia formosa	42.02	1.00e-108	387.00
IUUC-Pab-097751	Pongo abelii	82.21	0.00e+00	743.00
IUUC-Pca-100878	Procavia capensis	78.85	0.00e+00	731.00
IUUC-Pva-102337	Pteropus vampyrus	84.69	0.00e+00	786.00
IUUC-Rno-105255	Rattus norvegicus	79.40	0.00e+00	699.00
IUUC-Sha-106635	Sarcophilus harrisii	62.73	5.00e-157	547.00
IUUC-Ssc-116156	Sus scrofa	88.12	0.00e+00	849.00
IUUC-Tru-118662	Takifugu rubripes	45.98	8.00e-126	444.00
IUUC-Tsy-119337	Tarsius syrichta	78.63	0.00e+00	650.00
IUUC-Tbe-127388	Tupaia belangeri	82.48	0.00e+00	780.00
IUUC-Ttr-128767	Tursiops truncatus	92.29	0.00e+00	824.00
IUUC-Xtr-132443	Xenopus tropicalis	56.30	6.00e-138	484.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence