iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073673

UUCD1 version

UUC-OrA-00249

Ensembl Protein ID

ENSOANP00000024477.2

UniProt Accession

F6W616; F6W616_ORNAN

Protein Name

Uncharacterized protein

Gene Name

TRIM13

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000015539.2	ENSOANT00000024481.2	ENSOANP00000024477.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.10e-08	35.7	36	84

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw....pglknssskefrCPlCr 46
           C+iC++ f+d p+vlpC H f+++Cl+ +    +  +   s  f+CP+Cr
   Q: 36   CPICCSLFDD-PRVLPCSHNFCKKCLEGIldgnVRNMLWRSAPFKCPTCR 84
           ********99.**************97777888788888**********8 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MALSLCPAVA QRARRISSHS PGAEDVMELL EEDLTCPICC SLFDDPRVLP CSHNFCKKCL 60
EGILDGNVRN MLWRSAPFKC PTCRKEVSAT GVSSLQVNYS LKGIVEKYNK IKVSPKMPVC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCTTT CCCTGTGCCC AGCAGTTGCC CAGCGAGCCC GGAGGATAAG CAGCCACTCC 60
CCAGGTGCAG AGGTGAGCTA AGGGGCGAGG CTACCTTTAC AAATTCTTTG TATGCGAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0097038--C:perinuclear endoplasmic reticulum
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0010942--P:positive regulation of cell death
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016239--P:positive regulation of macroautophagy
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0051865--P:protein autoubiquitination
GO:0010332--P:response to gamma radiation
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002269	Ailuropoda melanoleuca	80.49	0.00e+00	647.00
IUUC-Apl-004168	Anas platyrhynchos	75.49	0.00e+00	636.00
IUUC-Aca-004395	Anolis carolinensis	70.10	1.00e-171	594.00
IUUC-Ame-011325	Astyanax mexicanus	47.68	2.00e-68	251.00
IUUC-Bta-012613	Bos taurus	81.62	0.00e+00	650.00
IUUC-Cja-018856	Callithrix jacchus	80.00	0.00e+00	690.00
IUUC-Cfa-021019	Canis familiaris	79.05	0.00e+00	650.00
IUUC-Cpo-021845	Cavia porcellus	79.41	0.00e+00	636.00
IUUC-Csa-023380	Chlorocebus sabaeus	79.90	0.00e+00	639.00
IUUC-Cho-024733	Choloepus hoffmanni	66.52	2.00e-71	262.00
IUUC-Dre-028675	Danio rerio	50.74	6.00e-112	396.00
IUUC-Dno-030018	Dasypus novemcinctus	79.66	0.00e+00	663.00
IUUC-Dor-030599	Dipodomys ordii	74.25	4.00e-106	376.00
IUUC-Ete-033134	Echinops telfairi	79.27	0.00e+00	665.00
IUUC-Eca-033931	Equus caballus	80.24	0.00e+00	638.00
IUUC-Eeu-034903	Erinaceus europaeus	79.02	0.00e+00	639.00
IUUC-Fca-035642	Felis catus	80.64	0.00e+00	637.00
IUUC-Fal-037108	Ficedula albicollis	75.74	0.00e+00	649.00
IUUC-Gga-040903	Gallus gallus	74.75	0.00e+00	634.00
IUUC-Ggo-044635	Gorilla gorilla	80.49	0.00e+00	648.00
IUUC-Hsa-046345	Homo sapiens	80.73	0.00e+00	651.00
IUUC-Itr-048220	Ictidomys tridecemlineatus	78.10	8.00e-179	619.00
IUUC-Lch-050599	Latimeria chalumnae	59.27	2.00e-138	484.00
IUUC-Loc-052378	Lepisosteus oculatus	60.95	3.00e-116	410.00
IUUC-Laf-053332	Loxodonta africana	80.39	0.00e+00	655.00
IUUC-Mcc-054705	Macaca mulatta	79.76	0.00e+00	642.00
IUUC-Meu-056825	Macropus eugenii	83.66	0.00e+00	711.00
IUUC-Mga-059528	Meleagris gallopavo	74.02	0.00e+00	643.00
IUUC-Mmr-060688	Microcebus murinus	80.24	0.00e+00	644.00
IUUC-Mdo-061882	Monodelphis domestica	81.02	0.00e+00	706.00
IUUC-Mmu-064352	Mus musculus	77.94	0.00e+00	652.00
IUUC-Mpu-066712	Mustela putorius furo	82.11	1.00e-174	604.00
IUUC-Mlu-068093	Myotis lucifugus	78.92	3.00e-180	623.00
IUUC-Nle-069310	Nomascus leucogenys	81.37	0.00e+00	650.00
IUUC-Ont-071759	Oreochromis niloticus	58.63	9.00e-110	389.00
IUUC-Ocu-074192	Oryctolagus cuniculus	80.24	0.00e+00	653.00
IUUC-Ola-087424	Oryzias latipes	58.06	1.00e-108	385.00
IUUC-Oga-088808	Otolemur garnettii	80.39	0.00e+00	641.00
IUUC-Oar-089553	Ovis aries	80.73	0.00e+00	647.00
IUUC-Ptr-090518	Pan troglodytes	80.24	0.00e+00	643.00
IUUC-Pan-092781	Papio anubis	79.76	0.00e+00	642.00
IUUC-Psi-093914	Pelodiscus sinensis	74.33	0.00e+00	643.00
IUUC-Pfo-096346	Poecilia formosa	54.52	1.00e-107	382.00
IUUC-Pca-100914	Procavia capensis	79.51	0.00e+00	671.00
IUUC-Pva-102728	Pteropus vampyrus	79.76	0.00e+00	638.00
IUUC-Rno-105922	Rattus norvegicus	77.21	2.00e-173	601.00
IUUC-Sha-107124	Sarcophilus harrisii	83.13	0.00e+00	722.00
IUUC-Sar-113607	Sorex araneus	77.32	2.00e-176	611.00
IUUC-Ssc-116355	Sus scrofa	81.13	0.00e+00	647.00
IUUC-Tgu-116476	Taeniopygia guttata	75.49	0.00e+00	647.00
IUUC-Tru-118737	Takifugu rubripes	57.83	1.00e-109	389.00
IUUC-Tsy-118908	Tarsius syrichta	79.51	0.00e+00	659.00
IUUC-Tbe-127258	Tupaia belangeri	80.98	0.00e+00	648.00
IUUC-Vpa-130138	Vicugna pacos	80.49	0.00e+00	645.00
IUUC-Xtr-132100	Xenopus tropicalis	58.74	1.00e-135	475.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence