iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-051745

Ensembl Protein ID

ENSLOCP00000021468.1

UniProt Accession

W5NLF9; W5NLF9_LEPOC

Genbank Protein ID

ENSLOCP00000021468

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01001683

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000017363.1	ENSLOCT00000021505.1	ENSLOCP00000021468.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	2.80e-15	56.1	498	544

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 4    lwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
            +l r+ p+SLqh+CR aI+rc++++++     LPLP++L+d+L++++y+
   Q: 498  VPLNRTFPFSLQHICRAAICRCTTYDGI---GLLPLPSMLQDFLKEYHYK 544
           5678999*********************...****************985 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MEKVGKMWSN LKNRCQNLFL PDGLSRSESM EMSSGRCGTD PSPSDPAPPR AASPPRGITP 60
LPLVSEGLQA AARRSHNCVS DIPQIVEITI DKESEDPRAA GGARLARRDS YSRHAPWGGK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGAAGG TGGGAAAGAT GTGGAGCAAC CTGAAGAACA GATGTCAGAA CCTGTTCCTT 60
CCGGATGGCT TGAGCCGGAG CGAGAGCATG GAGATGAGCT CGGGTAGGTG TGGCACAGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR022252--SOCS4/SOCS5_dom
IPR028420--SOCS5
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF12610--SOCS
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007259--P:JAK-STAT cascade
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000371	Aegilops tauschii	34.69	1.50e-01	29.30
IUUC-Aml-001789	Ailuropoda melanoleuca	77.44	2.00e-89	322.00
IUUC-Apl-003815	Anas platyrhynchos	72.25	0.00e+00	784.00
IUUC-Aca-004504	Anolis carolinensis	71.60	0.00e+00	704.00
IUUC-Ame-010677	Astyanax mexicanus	69.65	0.00e+00	676.00
IUUC-Bta-012338	Bos taurus	72.97	0.00e+00	758.00
IUUC-Bra-016839	Brassica rapa	35.14	3.20e+00	26.60
IUUC-Cja-019828	Callithrix jacchus	72.61	0.00e+00	748.00
IUUC-Cfa-020369	Canis familiaris	72.97	0.00e+00	762.00
IUUC-Cpo-021397	Cavia porcellus	72.26	0.00e+00	772.00
IUUC-Csa-023856	Chlorocebus sabaeus	72.61	0.00e+00	756.00
IUUC-Cho-024700	Choloepus hoffmanni	77.04	1.00e-89	323.00
IUUC-Dre-028262	Danio rerio	70.37	0.00e+00	641.00
IUUC-Dno-029019	Dasypus novemcinctus	72.79	0.00e+00	779.00
IUUC-Dor-030273	Dipodomys ordii	77.66	1.00e-89	323.00
IUUC-Eca-033867	Equus caballus	71.90	0.00e+00	776.00
IUUC-Eeu-035208	Erinaceus europaeus	76.92	1.00e-88	320.00
IUUC-Fca-035806	Felis catus	72.79	0.00e+00	766.00
IUUC-Fal-037117	Ficedula albicollis	71.75	0.00e+00	775.00
IUUC-Gmo-039066	Gadus morhua	88.02	4.00e-112	398.00
IUUC-Gga-040876	Gallus gallus	71.55	0.00e+00	776.00
IUUC-Gac-042149	Gasterosteus aculeatus	70.10	0.00e+00	674.00
IUUC-Ggo-045169	Gorilla gorilla	71.73	0.00e+00	751.00
IUUC-Hsa-045805	Homo sapiens	72.61	0.00e+00	756.00
IUUC-Hvu-047122	Hordeum vulgare	48.28	9.90e-02	30.40
IUUC-Itr-049048	Ictidomys tridecemlineatus	72.79	0.00e+00	776.00
IUUC-Lch-049686	Latimeria chalumnae	71.35	0.00e+00	738.00
IUUC-Laf-054124	Loxodonta africana	72.61	0.00e+00	776.00
IUUC-Mcc-055175	Macaca mulatta	72.61	0.00e+00	756.00
IUUC-Meu-056557	Macropus eugenii	70.77	0.00e+00	770.00
IUUC-Mtr-057670	Medicago truncatula	37.50	1.30e+00	27.30
IUUC-Mga-059214	Meleagris gallopavo	72.79	0.00e+00	780.00
IUUC-Mvi-060418	Microbotryum violaceum	30.86	1.30e-01	29.60
IUUC-Mmr-060613	Microcebus murinus	60.28	4.00e-159	554.00
IUUC-Mdo-062788	Monodelphis domestica	71.48	0.00e+00	761.00
IUUC-Mmu-064333	Mus musculus	73.32	0.00e+00	760.00
IUUC-Mpu-066048	Mustela putorius furo	72.97	0.00e+00	759.00
IUUC-Mlu-067430	Myotis lucifugus	72.61	0.00e+00	746.00
IUUC-Nle-069086	Nomascus leucogenys	72.61	0.00e+00	777.00
IUUC-Opr-070312	Ochotona princeps	72.89	0.00e+00	740.00
IUUC-Ont-072299	Oreochromis niloticus	71.48	0.00e+00	691.00
IUUC-Ocu-074123	Oryctolagus cuniculus	72.97	0.00e+00	738.00
IUUC-Ola-086934	Oryzias latipes	72.13	0.00e+00	700.00
IUUC-Oga-088535	Otolemur garnettii	72.26	0.00e+00	774.00
IUUC-Oar-089875	Ovis aries	72.79	0.00e+00	759.00
IUUC-Ptr-090541	Pan troglodytes	72.61	0.00e+00	756.00
IUUC-Pan-092416	Papio anubis	72.61	0.00e+00	756.00
IUUC-Psi-092960	Pelodiscus sinensis	71.38	0.00e+00	768.00
IUUC-Pma-094222	Petromyzon marinus	78.53	2.00e-84	306.00
IUUC-Pfo-096930	Poecilia formosa	71.33	0.00e+00	701.00
IUUC-Pab-098659	Pongo abelii	72.61	0.00e+00	757.00
IUUC-Pca-100222	Procavia capensis	71.55	0.00e+00	767.00
IUUC-Pva-102387	Pteropus vampyrus	72.44	0.00e+00	754.00
IUUC-Rno-105698	Rattus norvegicus	73.32	0.00e+00	760.00
IUUC-Sha-107234	Sarcophilus harrisii	70.42	0.00e+00	749.00
IUUC-Sar-113698	Sorex araneus	73.23	0.00e+00	705.00
IUUC-Ssc-115985	Sus scrofa	72.26	0.00e+00	770.00
IUUC-Tgu-116676	Taeniopygia guttata	73.27	0.00e+00	784.00
IUUC-Tru-118441	Takifugu rubripes	63.78	1.00e-163	569.00
IUUC-Tsy-119163	Tarsius syrichta	70.32	0.00e+00	735.00
IUUC-Tni-120436	Tetraodon nigroviridis	70.39	0.00e+00	685.00
IUUC-Tae-124846	Triticum aestivum	34.69	2.70e-01	28.50
IUUC-Tbe-127353	Tupaia belangeri	72.61	0.00e+00	760.00
IUUC-Ttr-128907	Tursiops truncatus	72.79	0.00e+00	746.00
IUUC-Vpa-130140	Vicugna pacos	72.97	0.00e+00	758.00
IUUC-Xtr-132817	Xenopus tropicalis	67.61	0.00e+00	730.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence