iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066439

Ensembl Protein ID

ENSMPUP00000009713.1

UniProt Accession

M3YEF6; M3YEF6_MUSPF

Genbank Protein ID

ENSMPUP00000009713

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01064998

Gene Name

UBE3C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000009787.1	ENSMPUT00000009870.1	ENSMPUP00000009713.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	5.80e-105	351.4	735	1072

Active Site

Position(s)	Description	Evidence
1040	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqd 84
            dlkkr++v++++     E+g+d gG++refl++l+k  +np+ g+f++++++    +p+  + + +    ++++flGr+lgkal++
   Q: 735  PDLKKRIRVHLLNahgldEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPSPAARMLVGD-SFARHYYFLGRMLGKALYE 820
           689**********99**9*******************************************999965.99***************** PP
   S: 85   grlldlplsksfyklllgk..klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneN 169
           + l++lp++ +f+++llg+  ++++++l+++dpe+yk+l ++k++ e d+eelgl++t+   ++ lge++++eLk gG++ipVt +N
   Q: 821  NMLVELPFAGFFLSKLLGTsaDVDIHHLASLDPEVYKNLLFLKSY-EGDVEELGLNFTVV--NNDLGEAQVVELKFGGKDIPVTSAN 904
           ******************9666889******************99.78999987777765..888********************** PP
   S: 170  keeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevlee 255
           + +Y++lv++yrl+++i++++ afr+G+ +v++le+l++F+++e+++li+G    i+++dlk++t+y ggy++d+p+i+ Fw+v+e+
   Q: 905  RIAYIHLVADYRLNRQIRQHCLAFRQGLANVVNLEWLRMFDQQEIQVLISGAqVPISLDDLKSFTNYSGGYSADHPVIRVFWRVVEG 991
           ****************************************************899******************************** PP
   S: 256  fsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           f++ee++++L+FvT++sr Pl Gf+el p  f+i++ +sd +rlP+++TC+n+LkLPe+  ++ l++kLlyAie ++gFels
   Q: 992  FTDEEKRKLLKFVTSCSRPPLLGFKELYPA-FCIHNGGSDlERLPTASTCMNLLKLPEFHDESLLRSKLLYAIECAAGFELS 1072
           ****************************88.*****99999**************************************985 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MRRCGVPAVE EEKASLLHRT QEERRKREEE RRRLKNAVII QSFIRGCRDR RQQHALRRSA 60
FDRCASASQP GGTFSVASGP NLTLLVRQLL FFYKQSEDSK RLIWMYQNLI KHSSLFVQQL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAAGATAAG ATAAAGTGCC TCAAGCTCAA AGGCCAGATA GAGACGCCTG GTGTCATTTG 60
CTCCTGTTTA CATATCGATG AGAAGATGCG GCGTCCCGGC TGTGGAGGTG AGATTAGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	36.29	7.00e-94	339.00
IUUC-Aml-001355	Ailuropoda melanoleuca	95.22	0.00e+00	1973.00
IUUC-Apl-003731	Anas platyrhynchos	88.12	0.00e+00	1858.00
IUUC-Aca-005248	Anolis carolinensis	86.99	0.00e+00	1866.00
IUUC-Aly-005768	Arabidopsis lyrata	35.54	3.00e-109	389.00
IUUC-Ath-006576	Arabidopsis thaliana	33.56	5.00e-109	389.00
IUUC-Ago-007748	Ashbya gossypii	41.90	1.00e-77	285.00
IUUC-Acl-008158	Aspergillus clavatus	38.38	3.00e-76	280.00
IUUC-Afl-008398	Aspergillus flavus	34.54	6.00e-78	286.00
IUUC-Afu-008937	Aspergillus fumigatus	35.05	5.00e-80	293.00
IUUC-Ani-009252	Aspergillus nidulans	39.15	3.00e-81	296.00
IUUC-Ang-009773	Aspergillus niger	34.02	3.00e-78	287.00
IUUC-Aor-009940	Aspergillus oryzae	34.54	7.00e-78	285.00
IUUC-Ate-010395	Aspergillus terreus	38.81	1.00e-76	281.00
IUUC-Ame-010769	Astyanax mexicanus	63.50	0.00e+00	1047.00
IUUC-Bgr-012269	Blumeria graminis	38.65	3.00e-75	275.00
IUUC-Bta-012841	Bos taurus	90.74	0.00e+00	1884.00
IUUC-Bci-013743	Botrytis cinerea	29.77	4.00e-85	310.00
IUUC-Bdi-014123	Brachypodium distachyon	46.57	5.00e-102	365.00
IUUC-Bol-015390	Brassica oleracea	34.07	3.00e-101	363.00
IUUC-Bra-016853	Brassica rapa	34.81	3.00e-108	386.00
IUUC-Cel-018638	Caenorhabditis elegans	39.37	4.00e-89	323.00
IUUC-Cja-019743	Callithrix jacchus	91.49	0.00e+00	1896.00
IUUC-Cfa-021031	Canis familiaris	95.15	0.00e+00	1972.00
IUUC-Cpo-022401	Cavia porcellus	90.17	0.00e+00	1887.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	43.73	2.00e-83	302.00
IUUC-Csa-024107	Chlorocebus sabaeus	92.79	0.00e+00	1925.00
IUUC-Cho-024750	Choloepus hoffmanni	82.08	0.00e+00	798.00
IUUC-Cin-025432	Ciona intestinalis	44.88	1.00e-97	350.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	34.21	2.00e-87	317.00
IUUC-Cne-026841	Cryptococcus neoformans	36.48	3.00e-94	340.00
IUUC-Cme-027265	Cyanidioschyzon merolae	46.86	2.00e-102	367.00
IUUC-Dre-028196	Danio rerio	76.59	0.00e+00	1556.00
IUUC-Dno-029024	Dasypus novemcinctus	92.42	0.00e+00	1938.00
IUUC-Dor-030483	Dipodomys ordii	90.60	0.00e+00	681.00
IUUC-Dse-031416	Dothistroma septosporum	33.73	3.00e-78	286.00
IUUC-Dme-031946	Drosophila melanogaster	37.92	0.00e+00	652.00
IUUC-Ete-032240	Echinops telfairi	80.05	2.00e-172	600.00
IUUC-Eca-033828	Equus caballus	93.41	0.00e+00	1953.00
IUUC-Eeu-034604	Erinaceus europaeus	85.77	6.00e-128	451.00
IUUC-Fca-035907	Felis catus	93.35	0.00e+00	1966.00
IUUC-Fal-037389	Ficedula albicollis	88.20	0.00e+00	1879.00
IUUC-Fox-037788	Fusarium oxysporum	36.53	1.00e-91	331.00
IUUC-Fso-038088	Fusarium solani	36.68	4.00e-91	330.00
IUUC-Gmo-039254	Gadus morhua	64.90	0.00e+00	1176.00
IUUC-Ggr-039941	Gaeumannomyces graminis	33.74	5.00e-83	302.00
IUUC-Gga-040310	Gallus gallus	88.39	0.00e+00	1880.00
IUUC-Gac-042054	Gasterosteus aculeatus	67.61	0.00e+00	1234.00
IUUC-Gma-042836	Glycine max	33.68	4.00e-102	366.00
IUUC-Ggo-045031	Gorilla gorilla	93.16	0.00e+00	1931.00
IUUC-Hsa-045880	Homo sapiens	93.07	0.00e+00	1929.00
IUUC-Hvu-047770	Hordeum vulgare	47.55	1.00e-103	370.00
IUUC-Itr-048555	Ictidomys tridecemlineatus	83.69	0.00e+00	679.00
IUUC-Kpa-049307	Komagataella pastoris	36.28	3.00e-64	240.00
IUUC-Lch-050403	Latimeria chalumnae	80.39	0.00e+00	1610.00
IUUC-Lpe-051428	Leersia perrieri	46.15	5.00e-95	342.00
IUUC-Loc-052218	Lepisosteus oculatus	79.53	0.00e+00	1643.00
IUUC-Lma-053096	Leptosphaeria maculans	38.06	4.00e-80	293.00
IUUC-Laf-054162	Loxodonta africana	88.73	0.00e+00	1677.00
IUUC-Mcc-055127	Macaca mulatta	92.88	0.00e+00	1925.00
IUUC-Meu-056187	Macropus eugenii	82.17	5.00e-105	375.00
IUUC-Mor-057021	Magnaporthe oryzae	34.32	2.00e-77	284.00
IUUC-Mpo-057570	Magnaporthe poae	36.24	9.00e-76	278.00
IUUC-Mtr-058154	Medicago truncatula	36.00	5.00e-104	372.00
IUUC-Mla-059124	Melampsora laricipopulina	48.03	1.00e-101	363.00
IUUC-Mga-059581	Meleagris gallopavo	88.11	0.00e+00	1875.00
IUUC-Mvi-060445	Microbotryum violaceum	37.70	1.00e-104	374.00
IUUC-Mmr-061360	Microcebus murinus	89.22	0.00e+00	1832.00
IUUC-Mdo-062194	Monodelphis domestica	88.99	0.00e+00	1888.00
IUUC-Mmu-064189	Mus musculus	90.73	0.00e+00	1922.00
IUUC-Mac-065275	Musa acuminata	49.39	6.00e-109	388.00
IUUC-Mlu-068228	Myotis lucifugus	89.65	0.00e+00	1890.00
IUUC-Nfi-068280	Neosartorya fischeri	38.85	9.00e-79	288.00
IUUC-Ncr-068869	Neurospora crassa	35.44	2.00e-81	297.00
IUUC-Nle-069687	Nomascus leucogenys	93.22	0.00e+00	1921.00
IUUC-Opr-070592	Ochotona princeps	75.00	1.00e-122	434.00
IUUC-Ont-071836	Oreochromis niloticus	76.78	0.00e+00	1587.00
IUUC-Oan-072800	Ornithorhynchus anatinus	88.58	0.00e+00	1876.00
IUUC-Ocu-074587	Oryctolagus cuniculus	93.07	0.00e+00	1934.00
IUUC-Oba-075006	Oryza barthii	48.18	6.00e-107	382.00
IUUC-Obr-076133	Oryza brachyantha	48.41	2.00e-106	381.00
IUUC-Ogl-077003	Oryza glaberrima	48.66	6.00e-107	382.00
IUUC-Ogu-078947	Oryza glumaepatula	48.66	6.00e-107	382.00
IUUC-Olo-080475	Oryza longistaminata	48.66	6.00e-107	382.00
IUUC-Ome-081342	Oryza meridionalis	45.66	2.00e-94	340.00
IUUC-Oni-082385	Oryza nivara	48.66	5.00e-107	382.00
IUUC-Opu-083176	Oryza punctata	48.66	6.00e-107	382.00
IUUC-Oru-084554	Oryza rufipogon	45.66	4.00e-94	339.00
IUUC-Osa-085355	Oryza sativa	48.66	5.00e-107	382.00
IUUC-Ola-087209	Oryzias latipes	75.56	0.00e+00	1545.00
IUUC-Olu-087699	Ostreococcus lucimarinus	43.13	3.00e-87	315.00
IUUC-Oga-088776	Otolemur garnettii	87.08	0.00e+00	1737.00
IUUC-Oar-089441	Ovis aries	89.91	0.00e+00	1865.00
IUUC-Ptr-091273	Pan troglodytes	92.98	0.00e+00	1928.00
IUUC-Pan-091981	Papio anubis	92.79	0.00e+00	1924.00
IUUC-Psi-093203	Pelodiscus sinensis	87.04	0.00e+00	1612.00
IUUC-Pma-094738	Petromyzon marinus	64.63	0.00e+00	1305.00
IUUC-Pno-095132	Phaeosphaeria nodorum	29.83	6.00e-61	229.00
IUUC-Ppa-095682	Physcomitrella patens	37.03	1.00e-111	397.00
IUUC-Pfo-097511	Poecilia formosa	77.06	0.00e+00	1599.00
IUUC-Pab-098634	Pongo abelii	89.06	0.00e+00	1849.00
IUUC-Pop-098928	Populus trichocarpa	35.14	2.00e-98	353.00
IUUC-Pca-100987	Procavia capensis	97.91	0.00e+00	791.00
IUUC-Ppe-102040	Prunus persica	35.33	6.00e-96	345.00
IUUC-Pva-103034	Pteropus vampyrus	87.76	0.00e+00	1811.00
IUUC-Pgr-103513	Puccinia graminis	39.55	7.00e-106	379.00
IUUC-Ptt-103967	Puccinia triticina	41.80	5.00e-94	339.00
IUUC-Pte-104105	Pyrenophora teres	34.38	2.00e-81	297.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	34.21	5.00e-80	293.00
IUUC-Rno-105380	Rattus norvegicus	89.23	0.00e+00	1648.00
IUUC-Sce-106446	Saccharomyces cerevisiae	41.01	2.00e-68	254.00
IUUC-Sha-107108	Sarcophilus harrisii	82.84	0.00e+00	1738.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	44.64	1.00e-96	347.00
IUUC-Spo-108097	Schizosaccharomyces pombe	44.36	1.00e-94	341.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	29.38	3.00e-83	303.00
IUUC-Smo-109537	Selaginella moellendorffii	36.73	2.00e-103	370.00
IUUC-Sit-110457	Setaria italica	48.53	9.00e-99	355.00
IUUC-Sly-111362	Solanum lycopersicum	36.15	2.00e-99	357.00
IUUC-Sar-113687	Sorex araneus	82.47	0.00e+00	906.00
IUUC-Sbi-113882	Sorghum bicolor	47.30	2.00e-95	344.00
IUUC-Sre-115038	Sporisorium reilianum	44.47	3.00e-98	353.00
IUUC-Ssc-115378	Sus scrofa	95.49	0.00e+00	750.00
IUUC-Tgu-116729	Taeniopygia guttata	88.12	0.00e+00	1871.00
IUUC-Tru-118068	Takifugu rubripes	75.47	0.00e+00	1550.00
IUUC-Tsy-118942	Tarsius syrichta	91.55	0.00e+00	705.00
IUUC-Tni-120732	Tetraodon nigroviridis	74.42	0.00e+00	1502.00
IUUC-Tca-121737	Theobroma cacao	34.98	9.00e-107	381.00
IUUC-Tre-121892	Trichoderma reesei	37.48	7.00e-88	318.00
IUUC-Tvi-122354	Trichoderma virens	35.16	2.00e-88	320.00
IUUC-Tae-125466	Triticum aestivum	47.30	5.00e-103	369.00
IUUC-Tur-126086	Triticum urartu	40.67	1.00e-93	338.00
IUUC-Tme-127102	Tuber melanosporum	35.81	2.00e-91	331.00
IUUC-Tbe-127351	Tupaia belangeri	79.78	0.00e+00	1500.00
IUUC-Ttr-129061	Tursiops truncatus	88.95	0.00e+00	1833.00
IUUC-Uma-129343	Ustilago maydis	44.96	7.00e-100	358.00
IUUC-Vda-129748	Verticillium dahliae	38.82	5.00e-81	296.00
IUUC-Vvi-131234	Vitis vinifera	35.74	8.00e-102	365.00
IUUC-Xtr-132094	Xenopus tropicalis	84.04	0.00e+00	1729.00
IUUC-Xma-133923	Xiphophorus maculatus	77.06	0.00e+00	1598.00
IUUC-Yli-134496	Yarrowia lipolytica	39.15	1.00e-88	320.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence