iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pma-094738

UUCD1 version

UUC-PeM-00424

Ensembl Protein ID

ENSPMAP00000001150.1

UniProt Accession

S4R7H0; S4R7H0_PETMA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000001024.1	ENSPMAT00000001155.1	ENSPMAP00000001150.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.20e-104	348.7	754	1091

Active Site

Position(s)	Description	Evidence
1059	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqd 84
            dl++r++v++++     E+g+d gG++refl++l+k  +np  g+f++++++    +p+    +     +++++flGr+lgkal++
   Q: 754  PDLRRRIRVHLLNahgldEAGIDGGGIFREFLNELLKTGFNPHQGFFRTTNQGLLYPNPEARLLVG-DGFTRHYYFLGRMLGKALYE 839
           588999999999999999*******************************99999888888888775.59****************** PP
   S: 85   grlldlplsksfyklllgk..klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneN 169
           + l++lp++ +f+++llg+  ++++++l+++dpe+y++l ++k++ + d+eelgl++t+   +++lge++++eLk gG++ipVt +N
   Q: 840  NMLVELPFAGFFLSKLLGTtgDVDIHHLASLDPEVYRNLLFLKSY-QGDVEELGLNFTVV--NNELGEAQVVELKAGGKDIPVTSAN 923
           ******************9777999********************.67999987777765..888********************** PP
   S: 170  keeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevlee 255
           + +Y++lv++yrl+++i++++ afr+G+ +vi+le+l++F+e+el++l++G    id++dlk++t+y ggyt+d+p+i+ Fw+v+e+
   Q: 924  RIAYIHLVADYRLNRQIRQHCLAFRQGLATVINLEWLRMFDEQELQVLLSGAqVPIDLQDLKNFTNYSGGYTADHPVIKVFWHVVEG 1010
           ****************************************************999******************************** PP
   S: 256  fsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           f++e+++++L+FvT++sr Pl Gf+el p  f++++  a+++rlP+++TC+n+LkLPe+ ++e+++ kLlyAie+++gFels
   Q: 1011 FTDEQKRKLLKFVTSCSRPPLLGFKELFPA-FCVHNgGADPERLPTASTCMNLLKLPEFLEEETMHGKLLYAIESAAGFELS 1091
           ****************************88.9****55566**************************************985 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

MFSFEGDFRT KPTVSLGGAS RREEKSSLLN RTLEERRKRE EERRRQKNAV VIQSFVRGCL 60
ERGKQHEKQR LEFDTLVSHA QRGGDETVLG DAAKLVALTQ RLLFFYDHRC DTTRLVWLCQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTCAGCT TTGAGGGAGA CTTCCGCACC AAGCCCACGG TGTCCCTTGG TGGGGCGAGC 60
CGGCGGGTAC GTGTGGCACC TGTGCAGGAA AATGCTTTGT GTGCCTTGTG GTCAGAGACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001355	Ailuropoda melanoleuca	64.15	0.00e+00	1284.00
IUUC-Apl-003731	Anas platyrhynchos	65.27	0.00e+00	1334.00
IUUC-Aca-005248	Anolis carolinensis	64.87	0.00e+00	1338.00
IUUC-Aly-005768	Arabidopsis lyrata	36.42	2.00e-109	389.00
IUUC-Ath-006576	Arabidopsis thaliana	34.38	1.00e-110	393.00
IUUC-Ago-007748	Ashbya gossypii	39.52	1.00e-72	266.00
IUUC-Acl-008158	Aspergillus clavatus	37.74	1.00e-73	270.00
IUUC-Afl-008398	Aspergillus flavus	37.95	5.00e-75	275.00
IUUC-Afu-008937	Aspergillus fumigatus	38.22	2.00e-76	279.00
IUUC-Ani-009252	Aspergillus nidulans	38.94	3.00e-80	292.00
IUUC-Ang-009773	Aspergillus niger	37.53	8.00e-75	274.00
IUUC-Aor-009940	Aspergillus oryzae	37.95	4.00e-75	275.00
IUUC-Ate-010395	Aspergillus terreus	37.10	1.00e-75	276.00
IUUC-Ame-010769	Astyanax mexicanus	52.92	0.00e+00	792.00
IUUC-Bgr-012269	Blumeria graminis	38.48	8.00e-74	269.00
IUUC-Bta-012841	Bos taurus	65.78	0.00e+00	1316.00
IUUC-Bci-013743	Botrytis cinerea	37.82	2.00e-80	293.00
IUUC-Bol-015390	Brassica oleracea	35.80	1.00e-105	376.00
IUUC-Bra-016853	Brassica rapa	36.57	7.00e-112	397.00
IUUC-Cel-018638	Caenorhabditis elegans	40.24	3.00e-90	325.00
IUUC-Cja-019743	Callithrix jacchus	63.36	0.00e+00	1270.00
IUUC-Cfa-021031	Canis familiaris	64.62	0.00e+00	1319.00
IUUC-Cpo-022401	Cavia porcellus	65.24	0.00e+00	1322.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	44.76	3.00e-83	300.00
IUUC-Csa-024107	Chlorocebus sabaeus	64.87	0.00e+00	1325.00
IUUC-Cho-024750	Choloepus hoffmanni	72.50	0.00e+00	718.00
IUUC-Cin-025432	Ciona intestinalis	45.63	6.00e-101	359.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	31.73	6.00e-86	311.00
IUUC-Cne-026841	Cryptococcus neoformans	36.59	8.00e-94	337.00
IUUC-Cme-027265	Cyanidioschyzon merolae	46.86	6.00e-103	367.00
IUUC-Dre-028196	Danio rerio	64.08	0.00e+00	1237.00
IUUC-Dno-029024	Dasypus novemcinctus	65.05	0.00e+00	1327.00
IUUC-Dor-030483	Dipodomys ordii	71.80	7.00e-148	516.00
IUUC-Dse-031416	Dothistroma septosporum	32.23	2.00e-78	286.00
IUUC-Dme-031946	Drosophila melanogaster	38.34	0.00e+00	688.00
IUUC-Ete-032240	Echinops telfairi	56.25	7.00e-108	384.00
IUUC-Eca-033828	Equus caballus	64.99	0.00e+00	1288.00
IUUC-Eeu-034604	Erinaceus europaeus	75.00	1.00e-110	392.00
IUUC-Fca-035907	Felis catus	65.24	0.00e+00	1330.00
IUUC-Fal-037389	Ficedula albicollis	65.42	0.00e+00	1344.00
IUUC-Fox-037788	Fusarium oxysporum	37.50	3.00e-92	331.00
IUUC-Fso-038088	Fusarium solani	36.25	3.00e-86	312.00
IUUC-Gmo-039254	Gadus morhua	54.99	0.00e+00	907.00
IUUC-Ggr-039941	Gaeumannomyces graminis	34.40	6.00e-82	297.00
IUUC-Gga-040310	Gallus gallus	65.63	0.00e+00	1342.00
IUUC-Gac-042054	Gasterosteus aculeatus	55.19	0.00e+00	935.00
IUUC-Ggo-045031	Gorilla gorilla	64.96	0.00e+00	1330.00
IUUC-Hsa-045880	Homo sapiens	65.05	0.00e+00	1330.00
IUUC-Kpa-049307	Komagataella pastoris	36.97	2.00e-64	239.00
IUUC-Lch-050403	Latimeria chalumnae	63.84	0.00e+00	1252.00
IUUC-Loc-052218	Lepisosteus oculatus	65.58	0.00e+00	1298.00
IUUC-Lma-053096	Leptosphaeria maculans	38.58	5.00e-82	298.00
IUUC-Laf-054162	Loxodonta africana	60.16	0.00e+00	1063.00
IUUC-Mcc-055127	Macaca mulatta	64.87	0.00e+00	1325.00
IUUC-Meu-056187	Macropus eugenii	75.22	2.00e-98	352.00
IUUC-Mor-057021	Magnaporthe oryzae	33.39	1.00e-75	276.00
IUUC-Mpo-057570	Magnaporthe poae	36.90	2.00e-77	282.00
IUUC-Mla-059124	Melampsora laricipopulina	46.31	4.00e-99	353.00
IUUC-Mga-059581	Meleagris gallopavo	65.41	0.00e+00	1332.00
IUUC-Mvi-060445	Microbotryum violaceum	37.48	6.00e-102	364.00
IUUC-Mmr-061360	Microcebus murinus	63.46	0.00e+00	1222.00
IUUC-Mdo-062194	Monodelphis domestica	62.28	0.00e+00	1318.00
IUUC-Mmu-064189	Mus musculus	65.05	0.00e+00	1316.00
IUUC-Mpu-066439	Mustela putorius furo	64.54	0.00e+00	1280.00
IUUC-Mlu-068228	Myotis lucifugus	63.47	0.00e+00	1288.00
IUUC-Nfi-068280	Neosartorya fischeri	38.22	1.00e-76	280.00
IUUC-Ncr-068869	Neurospora crassa	34.25	2.00e-80	293.00
IUUC-Nle-069687	Nomascus leucogenys	64.34	0.00e+00	1280.00
IUUC-Opr-070592	Ochotona princeps	89.50	1.00e-107	382.00
IUUC-Ont-071836	Oreochromis niloticus	64.60	0.00e+00	1278.00
IUUC-Oan-072800	Ornithorhynchus anatinus	64.96	0.00e+00	1337.00
IUUC-Ocu-074587	Oryctolagus cuniculus	64.96	0.00e+00	1325.00
IUUC-Ola-087209	Oryzias latipes	75.11	0.00e+00	1068.00
IUUC-Olu-087699	Ostreococcus lucimarinus	42.86	1.00e-85	308.00
IUUC-Oga-088776	Otolemur garnettii	63.51	0.00e+00	1224.00
IUUC-Oar-089441	Ovis aries	65.12	0.00e+00	1301.00
IUUC-Ptr-091273	Pan troglodytes	64.96	0.00e+00	1327.00
IUUC-Pan-091981	Papio anubis	64.96	0.00e+00	1327.00
IUUC-Psi-093203	Pelodiscus sinensis	62.19	0.00e+00	1112.00
IUUC-Pno-095132	Phaeosphaeria nodorum	35.43	3.00e-57	215.00
IUUC-Pfo-097511	Poecilia formosa	64.60	0.00e+00	1305.00
IUUC-Pab-098634	Pongo abelii	62.26	0.00e+00	1248.00
IUUC-Pop-098928	Populus trichocarpa	36.29	1.00e-98	353.00
IUUC-Pca-100987	Procavia capensis	86.95	0.00e+00	715.00
IUUC-Pva-103034	Pteropus vampyrus	61.62	0.00e+00	1196.00
IUUC-Pgr-103513	Puccinia graminis	38.81	3.00e-105	375.00
IUUC-Ptt-103967	Puccinia triticina	34.33	1.00e-92	333.00
IUUC-Pte-104105	Pyrenophora teres	34.56	9.00e-82	297.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	30.89	8.00e-81	294.00
IUUC-Rno-105380	Rattus norvegicus	62.50	0.00e+00	1102.00
IUUC-Sce-106446	Saccharomyces cerevisiae	39.81	3.00e-67	248.00
IUUC-Sha-107108	Sarcophilus harrisii	59.05	0.00e+00	1192.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	44.64	2.00e-94	338.00
IUUC-Spo-108097	Schizosaccharomyces pombe	43.90	8.00e-94	337.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	32.88	3.00e-80	292.00
IUUC-Sly-111362	Solanum lycopersicum	36.08	1.00e-103	369.00
IUUC-Sar-113687	Sorex araneus	64.89	0.00e+00	710.00
IUUC-Sre-115038	Sporisorium reilianum	45.05	4.00e-96	345.00
IUUC-Ssc-115378	Sus scrofa	84.76	0.00e+00	667.00
IUUC-Tgu-116729	Taeniopygia guttata	65.36	0.00e+00	1333.00
IUUC-Tru-118068	Takifugu rubripes	63.44	0.00e+00	1263.00
IUUC-Tsy-118942	Tarsius syrichta	87.89	3.00e-137	481.00
IUUC-Tni-120732	Tetraodon nigroviridis	63.21	0.00e+00	1241.00
IUUC-Tre-121892	Trichoderma reesei	36.16	3.00e-86	311.00
IUUC-Tvi-122354	Trichoderma virens	33.28	3.00e-87	315.00
IUUC-Tme-127102	Tuber melanosporum	35.57	4.00e-88	318.00
IUUC-Tbe-127351	Tupaia belangeri	64.04	0.00e+00	1031.00
IUUC-Ttr-129061	Tursiops truncatus	62.04	0.00e+00	1237.00
IUUC-Uma-129343	Ustilago maydis	44.44	6.00e-98	351.00
IUUC-Vda-129748	Verticillium dahliae	38.82	2.00e-78	285.00
IUUC-Vvi-131234	Vitis vinifera	37.19	3.00e-103	368.00
IUUC-Xtr-132094	Xenopus tropicalis	63.48	0.00e+00	1311.00
IUUC-Xma-133923	Xiphophorus maculatus	64.78	0.00e+00	1306.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence