iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067125

Ensembl Protein ID

ENSMLUP00000001176.2

UniProt Accession

G1NV90; G1NV90_MYOLU

Genbank Protein ID

ENSMLUP00000001176

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02054008

Gene Name

EML2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000001278.2	ENSMLUT00000001283.2	ENSMLUP00000001176.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-12	47.5	651	687

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH++ +t l++  d  ++v+ s+D  i  WD  t+++
   Q: 651  GHSSFITHLDWaRDsSRFVTNSGDYEILYWDSATCKQ 687
           8***********7779***************887765 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MAERGPAFCG LYDTSSLLQY CNDDNLSGTS GMEVDDRVSA LEQRLQLQED ELAVLKAALA 60
DALRRLRACE EQGAALRARS TPKGRAPPAA FPTRTPLNGS GPPRRVGGYA TSPSSPKKEA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAGC GCGGCCCGGC CTTCTGCGGC CTCTATGACA CGTCCTCGCT GCTTCAATAC 60
TGCAACGGTG AGAACCCCCC TCCACCCTTC CGACCCTGGC CCTGCCCAGC GCTGGACCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR000595--cNMP-bd_dom
IPR005108--HELP
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50042--CNMP_BINDING_3
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0072686--C:mitotic spindle
GO:0031115--P:negative regulation of microtubule polymerization
GO:0010968--P:regulation of microtubule nucleation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002155	Ailuropoda melanoleuca	73.61	0.00e+00	1028.00
IUUC-Aca-005316	Anolis carolinensis	60.98	0.00e+00	825.00
IUUC-Bta-013267	Bos taurus	75.36	0.00e+00	1075.00
IUUC-Cja-019146	Callithrix jacchus	69.29	0.00e+00	852.00
IUUC-Cfa-020267	Canis familiaris	74.97	0.00e+00	1083.00
IUUC-Dno-028961	Dasypus novemcinctus	73.12	0.00e+00	1046.00
IUUC-Eca-033785	Equus caballus	74.46	0.00e+00	1076.00
IUUC-Fca-036170	Felis catus	74.19	0.00e+00	1025.00
IUUC-Ggo-044669	Gorilla gorilla	74.04	0.00e+00	1018.00
IUUC-Hsa-046141	Homo sapiens	75.39	0.00e+00	1081.00
IUUC-Itr-048788	Ictidomys tridecemlineatus	74.19	0.00e+00	1059.00
IUUC-Laf-054137	Loxodonta africana	67.58	0.00e+00	791.00
IUUC-Mcc-055780	Macaca mulatta	70.87	0.00e+00	810.00
IUUC-Mmr-060853	Microcebus murinus	74.88	0.00e+00	1074.00
IUUC-Mdo-062224	Monodelphis domestica	65.95	0.00e+00	788.00
IUUC-Mmu-063860	Mus musculus	74.60	0.00e+00	1071.00
IUUC-Mpu-066043	Mustela putorius furo	74.73	0.00e+00	1070.00
IUUC-Nle-069618	Nomascus leucogenys	71.45	0.00e+00	962.00
IUUC-Oga-088048	Otolemur garnettii	71.38	0.00e+00	1008.00
IUUC-Oar-089907	Ovis aries	71.25	0.00e+00	856.00
IUUC-Pan-092082	Papio anubis	74.76	0.00e+00	1086.00
IUUC-Pab-097619	Pongo abelii	72.55	0.00e+00	894.00
IUUC-Pca-101070	Procavia capensis	61.31	0.00e+00	710.00
IUUC-Pva-102957	Pteropus vampyrus	67.49	0.00e+00	800.00
IUUC-Rno-105074	Rattus norvegicus	71.52	0.00e+00	870.00
IUUC-Sha-106692	Sarcophilus harrisii	64.17	0.00e+00	868.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence