iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000003192.2	ENSCJAT00000006160.2	ENSCJAP00000005849.2
ENSCJAG00000003192.2	ENSCJAT00000006173.2	ENSCJAP00000005861.2
ENSCJAG00000003192.2	ENSCJAT00000006156.2	ENSCJAP00000005845.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.40e-06	29.7	14	52

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw..........p 30
           C++Cl+ f+  p++  CgH f++ Cl ++          p
   Q: 14   CPLCLQLFDA-PVTAECGHSFCHICLRRMktepaaddtvP 52
           ********99.999************99855555555542 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MSAAPGLLHQ ELSCPLCLQL FDAPVTAECG HSFCHICLRR MKTEPAADDT VPHPAKLTSQ 60
HHNHKLTHEY TSGRQGPLRG SIWTPLSIYC EQDRALVCGV CASLGSHRGH RLLPAAEAHA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCGCCATGT CGGCTGCGCC CGGCCTCCTG CATCAGGAGC TGTCCTGCCC GCTGTGCCTG 60
CAGCTGTTCG ACGCTCCCGT GACAGCTGAG TGCGGCCACA GTTTTTGTCA CATCTGCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0030659--C:cytoplasmic vesicle membrane
GO:0042383--C:sarcolemma
GO:0001786--F:phosphatidylserine binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007517--P:muscle organ development
GO:0003012--P:muscle system process
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0043569--P:negative regulation of insulin-like growth factor receptor signaling pathway
GO:0010832--P:negative regulation of myotube differentiation
GO:0001778--P:plasma membrane repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051260--P:protein homooligomerization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002377	Ailuropoda melanoleuca	73.16	0.00e+00	636.00
IUUC-Aca-004755	Anolis carolinensis	60.08	2.00e-156	545.00
IUUC-Bta-013476	Bos taurus	70.52	9.00e-178	616.00
IUUC-Cfa-020155	Canis familiaris	82.44	0.00e+00	764.00
IUUC-Cpo-021646	Cavia porcellus	79.55	0.00e+00	735.00
IUUC-Csa-023855	Chlorocebus sabaeus	93.27	2.00e-176	611.00
IUUC-Dno-029142	Dasypus novemcinctus	81.61	0.00e+00	679.00
IUUC-Dor-030394	Dipodomys ordii	67.08	3.00e-85	308.00
IUUC-Ete-032801	Echinops telfairi	82.31	2.00e-63	236.00
IUUC-Eca-034378	Equus caballus	82.64	0.00e+00	744.00
IUUC-Eeu-034526	Erinaceus europaeus	75.94	0.00e+00	652.00
IUUC-Fca-036440	Felis catus	82.85	0.00e+00	772.00
IUUC-Ggo-045086	Gorilla gorilla	85.03	3.00e-171	593.00
IUUC-Hsa-046533	Homo sapiens	86.57	0.00e+00	764.00
IUUC-Itr-048959	Ictidomys tridecemlineatus	82.23	0.00e+00	762.00
IUUC-Laf-054479	Loxodonta africana	81.61	0.00e+00	748.00
IUUC-Mcc-055814	Macaca mulatta	84.36	0.00e+00	732.00
IUUC-Meu-056767	Macropus eugenii	67.44	1.00e-178	619.00
IUUC-Mmr-061616	Microcebus murinus	83.88	0.00e+00	778.00
IUUC-Mdo-062252	Monodelphis domestica	70.31	0.00e+00	650.00
IUUC-Mmu-063094	Mus musculus	79.96	0.00e+00	720.00
IUUC-Mpu-065885	Mustela putorius furo	75.26	0.00e+00	644.00
IUUC-Mlu-068150	Myotis lucifugus	50.35	6.00e-56	210.00
IUUC-Nle-069476	Nomascus leucogenys	86.80	0.00e+00	763.00
IUUC-Opr-070871	Ochotona princeps	79.06	8.00e-113	400.00
IUUC-Oan-072738	Ornithorhynchus anatinus	69.52	0.00e+00	636.00
IUUC-Ocu-074132	Oryctolagus cuniculus	80.81	8.00e-158	549.00
IUUC-Oga-088268	Otolemur garnettii	63.45	6.00e-147	513.00
IUUC-Oar-089555	Ovis aries	62.18	2.00e-139	489.00
IUUC-Ptr-090792	Pan troglodytes	86.57	0.00e+00	764.00
IUUC-Pan-092897	Papio anubis	86.16	0.00e+00	763.00
IUUC-Pab-098716	Pongo abelii	86.57	0.00e+00	764.00
IUUC-Pca-100618	Procavia capensis	72.52	0.00e+00	653.00
IUUC-Pva-102430	Pteropus vampyrus	73.76	0.00e+00	659.00
IUUC-Rno-105665	Rattus norvegicus	79.55	0.00e+00	743.00
IUUC-Sha-106854	Sarcophilus harrisii	58.52	5.00e-149	520.00
IUUC-Sar-113028	Sorex araneus	86.03	7.00e-139	486.00
IUUC-Ssc-116124	Sus scrofa	83.30	0.00e+00	744.00
IUUC-Tbe-127273	Tupaia belangeri	88.38	2.00e-123	436.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence