iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-044591

Ensembl Protein ID

ENSGGOP00000019480.1

UniProt Accession

G3RUK1; G3RUK1_GORGO

Protein Name

Uncharacterized protein

Gene Name

HIC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000027584.1	ENSGGOT00000022218.1	ENSGGOP00000023577.1
ENSGGOG00000027584.1	ENSGGOT00000029081.1	ENSGGOP00000019480.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.20e-12	48.5	34	93

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.d.vqpevfrallkFlYtgkl 65
           +Dvi+vv++  f+ahk vLaasS ++++l  +        +  +++ d v+p vfr +l+F+Ytg+l
   Q: 34   CDVIIVVQNALFRAHKNVLAASSAYLKSLVVH-------DNLLNLDhDmVSPAVFRLVLDFIYTGRL 93
           9*****************************77.......4566677678****************98 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

ECAGQTMLDT MEAPGHSRQL LLQLNNQRTK GFLCDVIIVV QNALFRAHKN VLAASSAYLK 60
SLVVHDNLLN LDHDMVSPAV FRLVLDFIYT GRLADGAEAA AAAAVAPGAE PSLGAVLAAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCGAGCAGC GGCGCGACAG TGCGGGGTCC CCTTTCTCCC AGAAGAGACA TCACCCACAC 60
AAACCTGACC TTCACGTGGG GCGCGGGACC TTGCGGGGTC CCAGCCGCAG GCGCCCCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR028424--HIC1
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0046872--F:metal ion binding
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008630--P:intrinsic apoptotic signaling pathway in response to DNA damage
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030178--P:negative regulation of Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001347	Ailuropoda melanoleuca	98.22	9.00e-143	500.00
IUUC-Aca-004680	Anolis carolinensis	56.78	4.00e-69	255.00
IUUC-Aor-010135	Aspergillus oryzae	32.14	3.90e-01	29.30
IUUC-Ame-010967	Astyanax mexicanus	60.24	3.00e-94	339.00
IUUC-Bta-013567	Bos taurus	100.00	2.00e-139	489.00
IUUC-Cja-019621	Callithrix jacchus	98.92	3.00e-46	176.00
IUUC-Cfa-020731	Canis familiaris	99.70	1.00e-147	517.00
IUUC-Cpo-021326	Cavia porcellus	93.28	2.00e-144	506.00
IUUC-Csa-023645	Chlorocebus sabaeus	99.70	4.00e-144	505.00
IUUC-Dre-028027	Danio rerio	57.64	6.00e-92	332.00
IUUC-Dno-028900	Dasypus novemcinctus	98.82	5.00e-143	501.00
IUUC-Fal-036980	Ficedula albicollis	71.88	2.00e-107	383.00
IUUC-Gga-040708	Gallus gallus	70.61	1.00e-105	377.00
IUUC-Hsa-046769	Homo sapiens	100.00	3.00e-140	492.00
IUUC-Itr-048627	Ictidomys tridecemlineatus	99.41	5.00e-147	514.00
IUUC-Loc-051883	Lepisosteus oculatus	63.47	7.00e-94	338.00
IUUC-Laf-053358	Loxodonta africana	99.41	2.00e-147	516.00
IUUC-Mcc-054981	Macaca mulatta	99.70	4.00e-144	504.00
IUUC-Meu-056181	Macropus eugenii	83.47	2.00e-77	283.00
IUUC-Mga-059592	Meleagris gallopavo	73.54	1.00e-102	366.00
IUUC-Mmr-061560	Microcebus murinus	98.52	2.00e-144	506.00
IUUC-Mdo-062511	Monodelphis domestica	81.45	4.00e-91	328.00
IUUC-Mmu-064258	Mus musculus	99.41	5.00e-146	511.00
IUUC-Mpu-065911	Mustela putorius furo	99.70	2.00e-147	516.00
IUUC-Mlu-067575	Myotis lucifugus	76.33	1.00e-98	353.00
IUUC-Ont-072493	Oreochromis niloticus	65.13	1.00e-80	293.00
IUUC-Ola-086584	Oryzias latipes	61.66	2.00e-89	323.00
IUUC-Oga-088774	Otolemur garnettii	97.85	6.00e-141	494.00
IUUC-Ptr-090491	Pan troglodytes	100.00	3.00e-122	431.00
IUUC-Pma-094179	Petromyzon marinus	70.51	4.00e-31	125.00
IUUC-Pfo-096282	Poecilia formosa	58.86	3.00e-87	316.00
IUUC-Pab-098488	Pongo abelii	100.00	2.00e-140	493.00
IUUC-Pca-100667	Procavia capensis	96.89	1.00e-143	503.00
IUUC-Pva-102421	Pteropus vampyrus	99.11	2.00e-150	526.00
IUUC-Rno-105528	Rattus norvegicus	99.41	7.00e-137	481.00
IUUC-Sar-113478	Sorex araneus	99.17	5.00e-120	425.00
IUUC-Ssc-115420	Sus scrofa	93.51	4.00e-149	521.00
IUUC-Tgu-116642	Taeniopygia guttata	71.88	6.00e-107	381.00
IUUC-Tru-118583	Takifugu rubripes	60.44	1.00e-85	310.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence