iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-069037

Ensembl Protein ID

ENSNLEP00000020850.1

UniProt Accession

G1S5R2; G1S5R2_NOMLE

Genbank Protein ID

ENSNLEP00000020850

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01111707

Gene Name

ATG16L2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000017146.2	ENSNLET00000021893.2	ENSNLEP00000020850.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-28	97.5	335	365
UBD/Beta-Prp	8.20e-46	156.5	333	619

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           H ++v++++f ++  ll++G+ D  i++W++
   Q: 335  HLSEVNAVRFgPNsSLLATGGADRLIHLWNV 365
           99*********7779***************7 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgh 93
           ++h s +++v f p++sllatg++d+ i +w+v    l   ++l+g  + +t+v+f+p+g   + +   +++++w +   +   tl+gh
   Q: 333  DAHLSEVNAVRFGPNSSLLATGGADRLIHLWNVVGSRLeaNQTLEGAGGSITSVDFDPSGYQVLAATYNQAAQLWKVGEAQSKETLSGH 421
           789999*****************************99988899*****************888888889******************** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           +d+v++ +f  +++  v+Gs+drt++ wdl   +c++ t ++ +    c  v + + +++sG++D+++r+Wd++   + +      +++
   Q: 422  KDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSR-TINVLS---YCNDVVCGDHIIISGHNDQKIRFWDSRGPHCTQVIP--VQGR 504
           ************************************9.666655...4555555556*************************5..589* PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlqtgec.....vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
           v+sls+++++ +l+s+s+d+t+k+ dl+ +++      + +++ +d++k   fsp+  + + gs+Dg ++iWd+++g+l + lq+++  
   Q: 505  VTSLSLSHDQLHLLSCSRDNTLKVIDLRVSNIrqvfrADGFKCGSDWTK-AVFSPDRSYALAGSCDGALYIWDVDTGKLESRLQGPHCA 592
           ****************************888833334444555556666.8899*********************************77 PP
   S: 267  visvavlsfgdnvlvlgsedskvniwk 293
            +   +++++++++v++++  kv +w+
   Q: 593  AVNAVAWCYSGSHVVSVDQGRKVVLWQ 619
           7777778****************9995 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MAGPGVPGAP AARWKRHIVR QLRLRDRTQK ALFLELVPAY NHLLEKAELL DKFSKKVQPE 60
PNSVTPTTHQ GPWEESELDS DQVPSLAALR VKWQEEEEGL RLVCGEMAYQ VVEKSAALGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGGCGGGAG GAACGCGCCG CGAGGCGGAA GAGCGCGGCC ATGGCGGGGC CCGGCGTTCC 60
CGGCGCCCCC GCAGCCCGCT GGAAACGCCA CATTGTGCGG CAGCTGCGGC TTCGGGACCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm

KEGG

nle:100585982

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001470	Ailuropoda melanoleuca	68.83	0.00e+00	756.00
IUUC-Atr-003073	Amborella trichopoda	31.76	2.00e-27	116.00
IUUC-Ame-011152	Astyanax mexicanus	41.88	4.00e-117	415.00
IUUC-Bta-013118	Bos taurus	85.95	0.00e+00	953.00
IUUC-Cja-020002	Callithrix jacchus	91.29	0.00e+00	1016.00
IUUC-Cfa-020878	Canis familiaris	83.20	0.00e+00	934.00
IUUC-Cpo-022476	Cavia porcellus	84.25	0.00e+00	914.00
IUUC-Csa-024134	Chlorocebus sabaeus	94.85	0.00e+00	1060.00
IUUC-Cho-024853	Choloepus hoffmanni	71.21	6.00e-179	620.00
IUUC-Dre-027949	Danio rerio	42.20	6.00e-129	454.00
IUUC-Dno-029683	Dasypus novemcinctus	85.44	0.00e+00	779.00
IUUC-Dor-030897	Dipodomys ordii	79.16	0.00e+00	945.00
IUUC-Ete-032957	Echinops telfairi	93.63	4.00e-132	464.00
IUUC-Eca-033303	Equus caballus	90.43	8.00e-164	569.00
IUUC-Eeu-035336	Erinaceus europaeus	74.01	9.00e-154	536.00
IUUC-Fca-036232	Felis catus	85.81	0.00e+00	1012.00
IUUC-Gmo-038880	Gadus morhua	50.70	1.00e-71	263.00
IUUC-Gac-042500	Gasterosteus aculeatus	41.14	3.00e-96	345.00
IUUC-Ggo-045130	Gorilla gorilla	98.51	0.00e+00	751.00
IUUC-Hsa-046359	Homo sapiens	98.52	0.00e+00	1040.00
IUUC-Itr-048780	Ictidomys tridecemlineatus	87.07	0.00e+00	987.00
IUUC-Lch-050669	Latimeria chalumnae	54.22	2.00e-95	342.00
IUUC-Loc-052789	Lepisosteus oculatus	43.66	1.00e-115	409.00
IUUC-Laf-053699	Loxodonta africana	86.56	0.00e+00	957.00
IUUC-Mcc-055657	Macaca mulatta	90.15	0.00e+00	947.00
IUUC-Meu-056639	Macropus eugenii	49.80	9.00e-109	387.00
IUUC-Mmr-061314	Microcebus murinus	81.19	0.00e+00	863.00
IUUC-Mdo-061841	Monodelphis domestica	63.71	0.00e+00	691.00
IUUC-Mmu-064065	Mus musculus	83.20	0.00e+00	953.00
IUUC-Mpu-066742	Mustela putorius furo	83.71	0.00e+00	913.00
IUUC-Mlu-067019	Myotis lucifugus	88.34	0.00e+00	677.00
IUUC-Opr-071039	Ochotona princeps	82.88	0.00e+00	913.00
IUUC-Oan-073431	Ornithorhynchus anatinus	72.22	3.00e-139	488.00
IUUC-Ocu-074772	Oryctolagus cuniculus	85.62	0.00e+00	852.00
IUUC-Ola-086964	Oryzias latipes	52.96	8.00e-84	303.00
IUUC-Oga-088188	Otolemur garnettii	87.08	0.00e+00	908.00
IUUC-Oar-090231	Ovis aries	79.74	0.00e+00	927.00
IUUC-Ptr-091434	Pan troglodytes	94.91	0.00e+00	989.00
IUUC-Pan-091868	Papio anubis	95.96	0.00e+00	1041.00
IUUC-Psi-093652	Pelodiscus sinensis	63.89	6.00e-165	573.00
IUUC-Pfo-096960	Poecilia formosa	42.60	1.00e-103	370.00
IUUC-Pab-097776	Pongo abelii	97.03	0.00e+00	998.00
IUUC-Pca-100220	Procavia capensis	66.34	0.00e+00	633.00
IUUC-Ppe-101790	Prunus persica	31.45	2.00e-43	170.00
IUUC-Pva-103135	Pteropus vampyrus	87.46	0.00e+00	881.00
IUUC-Rno-105529	Rattus norvegicus	81.67	0.00e+00	980.00
IUUC-Sha-107062	Sarcophilus harrisii	64.33	0.00e+00	724.00
IUUC-Sar-113109	Sorex araneus	67.00	8.00e-133	466.00
IUUC-Ssc-115271	Sus scrofa	87.28	0.00e+00	938.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence