iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059924

UUCD1 version

UUC-MeG-00141

Ensembl Protein ID

ENSMGAP00000002535.2

UniProt Accession

G1MV89; G1MV89_MELGA

Protein Name

Uncharacterized protein

Gene Name

MDM4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000002885.2	ENSMGAT00000003215.2	ENSMGAP00000002535.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	60.45	7.00e-164	574.00	IUUC-Hsa-046950

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MTSSSSAQHP TAENACRITL GQANQVRPKL PLLKILQAAG AQGETFTLKE VMHYLGQYIM 60
VRQLYDKRQQ HMVYCGGDQL GELLGLESFS VKDPSPVYDM LKRNLTSAAM TATNAAQNLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACATCTT CAAGCTCTGC CCAGCATCCA ACAGCTGAGA ACGCCTGCAG AATCACTCTT 60
GGACAAGCTA ACCAGGTAAT TATCTCCCCC ACTTATCTTC ATTGCTTTCT CCTCACTAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR001370--BIR_rpt
IPR015458--MDM4
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2

Pfam

PF02201--SWIB

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0008283--P:cell proliferation
GO:0071456--P:cellular response to hypoxia
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0045023--P:G0 to G1 transition
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0042177--P:negative regulation of protein catabolic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006461--P:protein complex assembly
GO:0050821--P:protein stabilization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001467	Ailuropoda melanoleuca	59.51	3.00e-155	541.00
IUUC-Apl-003800	Anas platyrhynchos	88.43	0.00e+00	808.00
IUUC-Aca-004608	Anolis carolinensis	60.62	6.00e-154	536.00
IUUC-Ame-010869	Astyanax mexicanus	47.62	3.00e-110	391.00
IUUC-Bta-013287	Bos taurus	59.63	9.00e-167	579.00
IUUC-Cja-019305	Callithrix jacchus	59.23	2.00e-151	528.00
IUUC-Cfa-020393	Canis familiaris	59.72	1.00e-161	561.00
IUUC-Cpo-022166	Cavia porcellus	58.55	4.00e-148	517.00
IUUC-Csa-023654	Chlorocebus sabaeus	60.85	1.00e-158	552.00
IUUC-Cho-024403	Choloepus hoffmanni	55.39	9.00e-75	273.00
IUUC-Dre-027754	Danio rerio	47.01	3.00e-119	421.00
IUUC-Dno-029630	Dasypus novemcinctus	59.11	1.00e-162	565.00
IUUC-Dor-031064	Dipodomys ordii	46.14	2.00e-120	425.00
IUUC-Ete-032901	Echinops telfairi	54.56	7.00e-153	533.00
IUUC-Eca-034234	Equus caballus	60.65	3.00e-177	614.00
IUUC-Eeu-035015	Erinaceus europaeus	54.01	4.00e-57	215.00
IUUC-Fca-036587	Felis catus	59.43	3.00e-162	564.00
IUUC-Fal-036906	Ficedula albicollis	72.48	0.00e+00	672.00
IUUC-Gmo-038646	Gadus morhua	44.29	4.00e-106	377.00
IUUC-Gga-040124	Gallus gallus	92.28	0.00e+00	642.00
IUUC-Gac-042397	Gasterosteus aculeatus	46.46	5.00e-115	407.00
IUUC-Ggo-045505	Gorilla gorilla	60.24	7.00e-159	553.00
IUUC-Hsa-046950	Homo sapiens	60.45	1.00e-159	555.00
IUUC-Itr-048886	Ictidomys tridecemlineatus	58.82	2.00e-158	551.00
IUUC-Lch-050141	Latimeria chalumnae	52.31	4.00e-128	451.00
IUUC-Loc-051921	Lepisosteus oculatus	49.31	1.00e-120	426.00
IUUC-Laf-054281	Loxodonta africana	58.42	3.00e-157	548.00
IUUC-Mcc-055462	Macaca mulatta	57.69	2.00e-143	501.00
IUUC-Meu-056294	Macropus eugenii	62.80	2.00e-125	442.00
IUUC-Mmr-061428	Microcebus murinus	59.84	1.00e-169	588.00
IUUC-Mdo-062643	Monodelphis domestica	61.45	4.00e-171	593.00
IUUC-Mmu-063229	Mus musculus	59.23	8.00e-156	543.00
IUUC-Mpu-065782	Mustela putorius furo	59.80	2.00e-157	548.00
IUUC-Mlu-068105	Myotis lucifugus	55.51	2.00e-152	531.00
IUUC-Nle-069549	Nomascus leucogenys	60.45	6.00e-160	556.00
IUUC-Opr-070568	Ochotona princeps	58.03	1.00e-150	525.00
IUUC-Ont-072276	Oreochromis niloticus	47.20	6.00e-123	433.00
IUUC-Oan-072787	Ornithorhynchus anatinus	63.03	2.00e-162	565.00
IUUC-Ocu-074912	Oryctolagus cuniculus	58.01	5.00e-159	553.00
IUUC-Ola-087037	Oryzias latipes	45.14	3.00e-106	378.00
IUUC-Oga-088953	Otolemur garnettii	57.86	2.00e-150	525.00
IUUC-Oar-089202	Ovis aries	58.22	2.00e-168	585.00
IUUC-Ptr-090964	Pan troglodytes	60.65	2.00e-160	558.00
IUUC-Pan-091975	Papio anubis	60.65	5.00e-162	563.00
IUUC-Psi-093558	Pelodiscus sinensis	75.10	0.00e+00	657.00
IUUC-Pfo-096454	Poecilia formosa	47.96	3.00e-123	434.00
IUUC-Pab-098123	Pongo abelii	60.45	2.00e-160	558.00
IUUC-Pca-101112	Procavia capensis	55.47	3.00e-145	508.00
IUUC-Pva-103098	Pteropus vampyrus	57.26	2.00e-151	528.00
IUUC-Rno-105930	Rattus norvegicus	60.12	3.00e-154	538.00
IUUC-Sha-107512	Sarcophilus harrisii	62.04	1.00e-157	548.00
IUUC-Sar-113584	Sorex araneus	54.93	1.00e-140	492.00
IUUC-Tgu-116766	Taeniopygia guttata	72.96	9.00e-135	472.00
IUUC-Tru-117829	Takifugu rubripes	47.66	1.00e-116	412.00
IUUC-Tsy-119268	Tarsius syrichta	56.41	3.00e-65	242.00
IUUC-Tni-120204	Tetraodon nigroviridis	46.76	4.00e-110	391.00
IUUC-Tbe-127840	Tupaia belangeri	57.24	3.00e-78	285.00
IUUC-Ttr-128863	Tursiops truncatus	58.25	1.00e-159	555.00
IUUC-Vpa-130718	Vicugna pacos	60.60	1.00e-157	549.00
IUUC-Xtr-132320	Xenopus tropicalis	47.94	2.00e-99	355.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence