iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000014951.4	ENSCAFT00000023738.4	ENSCAFP00000022033.3
ENSCAFG00000014951.4	ENSCAFT00000043831.1	ENSCAFP00000036806.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.80e-16	59.7	830	870

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C vC +gg+    l++Ce C  +fHp+Cl++     +p+ + w+C++Cr
   Q: 830  WCFVCSKGGS----LLCCESCPAAFHPDCLNID----MPDGS-WFCNDCR 870
           8*********....*******************....9***8.******8 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

QKNPLSVQKV VECIKMKQAP EILGNTNGKT QNCEVNRECS VFLSKAHLST SLQEGVMQKF 60
NGHDALPFIP SEKLKDLTSR VFNGEPGAHD AKLRFESQEG KGLGTPPNTT PIKNGSPEIK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAAAAAATC CTCTTTCTGT TCAGAAAGTT GTAGAGTGCA TAAAGATGAA GCAGGCACCA 60
GAAATCCTTG GCAATACAAA CGGAAAGACT CAGAACTGTG AAGTGAATCG TGAATGTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR006560--AWS_dom
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51215--AWS
PS50118--HMG_BOX_2
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
PS50089--ZF_RING_2

Pfam

PF00505--HMG_box
PF00855--PWWP
PF00856--SET

SMART

SM00570--AWS
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00184--RING
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0043565--F:sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0003289--P:atrial septum primum morphogenesis
GO:0003290--P:atrial septum secundum morphogenesis
GO:0060348--P:bone development
GO:0010452--P:histone H3-K36 methylation
GO:0034770--P:histone H4-K20 methylation
GO:0003149--P:membranous septum morphogenesis
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0048298--P:positive regulation of isotype switching to IgA isotypes
GO:2001032--P:regulation of double-strand break repair via nonhomologous end joining
GO:0070201--P:regulation of establishment of protein localization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002181	Ailuropoda melanoleuca	97.28	0.00e+00	2571.00
IUUC-Apl-003677	Anas platyrhynchos	80.48	0.00e+00	2125.00
IUUC-Aca-004278	Anolis carolinensis	76.22	0.00e+00	1387.00
IUUC-Ame-011932	Astyanax mexicanus	71.22	0.00e+00	1031.00
IUUC-Bta-012522	Bos taurus	86.57	0.00e+00	2268.00
IUUC-Cja-018908	Callithrix jacchus	90.79	0.00e+00	2363.00
IUUC-Cpo-021982	Cavia porcellus	88.27	0.00e+00	2351.00
IUUC-Csa-023807	Chlorocebus sabaeus	91.09	0.00e+00	2385.00
IUUC-Cho-024405	Choloepus hoffmanni	73.98	0.00e+00	730.00
IUUC-Csv-026298	Ciona savignyi	40.00	8.00e-59	221.00
IUUC-Dre-027492	Danio rerio	70.62	0.00e+00	1064.00
IUUC-Dno-030020	Dasypus novemcinctus	86.47	0.00e+00	2051.00
IUUC-Dor-031103	Dipodomys ordii	83.48	0.00e+00	2153.00
IUUC-Ete-032488	Echinops telfairi	82.40	0.00e+00	2133.00
IUUC-Eca-034066	Equus caballus	93.76	0.00e+00	2539.00
IUUC-Eeu-035199	Erinaceus europaeus	71.92	0.00e+00	765.00
IUUC-Fca-035434	Felis catus	89.08	0.00e+00	2049.00
IUUC-Fal-037113	Ficedula albicollis	78.53	0.00e+00	2130.00
IUUC-Gmo-039686	Gadus morhua	71.23	0.00e+00	1017.00
IUUC-Gga-040273	Gallus gallus	78.55	0.00e+00	2103.00
IUUC-Gac-042123	Gasterosteus aculeatus	50.82	0.00e+00	1244.00
IUUC-Ggo-044643	Gorilla gorilla	91.22	0.00e+00	2415.00
IUUC-Hsa-046380	Homo sapiens	91.07	0.00e+00	2374.00
IUUC-Itr-048658	Ictidomys tridecemlineatus	91.01	0.00e+00	1446.00
IUUC-Lch-050217	Latimeria chalumnae	66.29	0.00e+00	1731.00
IUUC-Loc-052766	Lepisosteus oculatus	58.03	0.00e+00	1275.00
IUUC-Laf-053780	Loxodonta africana	89.52	0.00e+00	2454.00
IUUC-Mcc-054928	Macaca mulatta	91.17	0.00e+00	2416.00
IUUC-Meu-056184	Macropus eugenii	73.91	0.00e+00	785.00
IUUC-Mga-059576	Meleagris gallopavo	78.97	0.00e+00	2094.00
IUUC-Mmr-061045	Microcebus murinus	91.27	0.00e+00	2464.00
IUUC-Mdo-062576	Monodelphis domestica	82.72	0.00e+00	2217.00
IUUC-Mmu-063640	Mus musculus	89.74	0.00e+00	2354.00
IUUC-Mac-065303	Musa acuminata	28.04	4.00e-11	63.50
IUUC-Mpu-066512	Mustela putorius furo	96.59	0.00e+00	2540.00
IUUC-Mlu-067280	Myotis lucifugus	79.51	0.00e+00	1093.00
IUUC-Nle-069896	Nomascus leucogenys	90.97	0.00e+00	2288.00
IUUC-Ont-072197	Oreochromis niloticus	73.00	0.00e+00	1040.00
IUUC-Oan-072724	Ornithorhynchus anatinus	78.55	0.00e+00	1371.00
IUUC-Ocu-074758	Oryctolagus cuniculus	87.54	0.00e+00	2313.00
IUUC-Ogl-077641	Oryza glaberrima	27.33	1.00e-09	57.40
IUUC-Oin-079557	Oryza indica	27.33	1.00e-09	57.40
IUUC-Olo-080702	Oryza longistaminata	41.94	2.00e-45	177.00
IUUC-Opu-083371	Oryza punctata	42.31	8.00e-47	182.00
IUUC-Oga-088702	Otolemur garnettii	90.96	0.00e+00	2113.00
IUUC-Oar-089736	Ovis aries	80.36	0.00e+00	1955.00
IUUC-Ptr-091055	Pan troglodytes	91.00	0.00e+00	2374.00
IUUC-Pan-092752	Papio anubis	94.35	0.00e+00	1430.00
IUUC-Psi-093620	Pelodiscus sinensis	80.27	0.00e+00	2136.00
IUUC-Pfo-097464	Poecilia formosa	50.90	0.00e+00	1210.00
IUUC-Pab-098051	Pongo abelii	90.85	0.00e+00	2401.00
IUUC-Pop-099927	Populus trichocarpa	28.96	1.00e-11	65.50
IUUC-Pca-100273	Procavia capensis	88.85	0.00e+00	2367.00
IUUC-Pva-102473	Pteropus vampyrus	78.59	0.00e+00	1964.00
IUUC-Rno-105056	Rattus norvegicus	89.10	0.00e+00	2365.00
IUUC-Sha-107494	Sarcophilus harrisii	83.94	0.00e+00	2208.00
IUUC-Sar-113310	Sorex araneus	90.52	0.00e+00	1886.00
IUUC-Sbi-114581	Sorghum bicolor	33.33	2.00e-09	56.20
IUUC-Ssc-116344	Sus scrofa	85.18	0.00e+00	2294.00
IUUC-Tgu-116786	Taeniopygia guttata	80.39	0.00e+00	2126.00
IUUC-Tru-117638	Takifugu rubripes	50.22	0.00e+00	1244.00
IUUC-Tsy-118937	Tarsius syrichta	92.98	0.00e+00	1540.00
IUUC-Tni-120452	Tetraodon nigroviridis	70.14	0.00e+00	1041.00
IUUC-Tae-125237	Triticum aestivum	29.45	2.00e-07	49.70
IUUC-Tbe-127291	Tupaia belangeri	87.29	0.00e+00	1538.00
IUUC-Ttr-129017	Tursiops truncatus	83.92	0.00e+00	1779.00
IUUC-Xtr-132673	Xenopus tropicalis	67.00	0.00e+00	1762.00
IUUC-Xma-133695	Xiphophorus maculatus	73.90	0.00e+00	1016.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence