iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000004330.2	ENSNLET00000005606.2	ENSNLEP00000005330.2
ENSNLEG00000004330.2	ENSNLET00000005598.2	ENSNLEP00000005322.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.70e-16	59.5	505	549

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C vC++gge    l++C+ C + +H +Cl+++  +e pn e w Cp+C+
   Q: 505  EFCRVCKDGGE----LLCCDTCPSSYHIHCLNPP-LPEIPNGE-WLCPRCT 549
           58*********....*******************.*******8.******6 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MGERRQGSGQ LPEVGLVWPG RPISGIYSSL FVCFCPGYQL PSVQSIAVLF RGIWDKRWGI 60
KSKASGLGPN LLLLIFSLPT TLCQIYVENE EDPEEDLSET ETPKLKKKKK PKKPRDPKIP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGAGAGA GGAGGCAGGG GTCTGGACAG CTGCCCGAGG TGGGCCTGGT CTGGCCTGGC 60
AGGCCTATTT CGGGTATATA CAGCTCTCTC TTTGTCTGTT TTTGTCCTGG GTATCAGCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028725--CHD4
IPR012957--CHD_C2
IPR012958--CHD_N
IPR000953--Chromo/chromo_shadow_dom
IPR023780--Chromo_domain
IPR016197--Chromodomain-like
IPR002464--DNA/RNA_helicase_DEAH_CS
IPR009462--DUF1086
IPR009463--DUF1087
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR000330--SNF2_N
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50013--CHROMO_2
PS00690--DEAH_ATP_HELICASE
PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF08074--CHDCT2
PF08073--CHDNT
PF00385--Chromo
PF06461--DUF1086
PF06465--DUF1087
PF00271--Helicase_C
PF00628--PHD
PF00176--SNF2_N

SMART

SM00298--CHROMO
SM00487--DEXDc
SM01146--DUF1086
SM01147--DUF1087
SM00490--HELICc
SM00249--PHD

Gene Ontology

GO:0005813--C:centrosome
GO:0005737--C:cytoplasm
GO:0016020--C:membrane
GO:0000790--C:nuclear chromatin
GO:0016581--C:NuRD complex
GO:0005524--F:ATP binding
GO:0008026--F:ATP-dependent helicase activity
GO:0031492--F:nucleosomal DNA binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980--F:RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0043044--P:ATP-dependent chromatin remodeling
GO:0006355--P:regulation of transcription, DNA-templated
GO:0051225--P:spindle assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001361	Ailuropoda melanoleuca	98.13	0.00e+00	3028.00
IUUC-Apl-004175	Anas platyrhynchos	89.41	0.00e+00	2687.00
IUUC-Aca-004774	Anolis carolinensis	88.33	0.00e+00	2741.00
IUUC-Ame-011098	Astyanax mexicanus	79.61	0.00e+00	2369.00
IUUC-Bta-013220	Bos taurus	96.94	0.00e+00	2857.00
IUUC-Cja-019510	Callithrix jacchus	93.97	0.00e+00	2734.00
IUUC-Cfa-020422	Canis familiaris	97.49	0.00e+00	2911.00
IUUC-Cpo-021704	Cavia porcellus	96.70	0.00e+00	2890.00
IUUC-Csa-023625	Chlorocebus sabaeus	97.87	0.00e+00	2916.00
IUUC-Cho-024361	Choloepus hoffmanni	93.04	0.00e+00	1535.00
IUUC-Dre-027692	Danio rerio	83.04	0.00e+00	1963.00
IUUC-Dno-029656	Dasypus novemcinctus	97.22	0.00e+00	2884.00
IUUC-Dor-030354	Dipodomys ordii	95.69	0.00e+00	1880.00
IUUC-Eca-034112	Equus caballus	97.54	0.00e+00	2922.00
IUUC-Fca-036056	Felis catus	97.60	0.00e+00	2912.00
IUUC-Fal-037312	Ficedula albicollis	93.92	0.00e+00	2279.00
IUUC-Gga-040216	Gallus gallus	90.50	0.00e+00	2788.00
IUUC-Gac-042478	Gasterosteus aculeatus	77.03	0.00e+00	1996.00
IUUC-Ggo-044428	Gorilla gorilla	88.43	0.00e+00	2593.00
IUUC-Hsa-045908	Homo sapiens	99.63	0.00e+00	3019.00
IUUC-Itr-048002	Ictidomys tridecemlineatus	97.20	0.00e+00	2877.00
IUUC-Lch-049948	Latimeria chalumnae	76.31	0.00e+00	1878.00
IUUC-Mcc-055773	Macaca mulatta	99.52	0.00e+00	3004.00
IUUC-Mga-059633	Meleagris gallopavo	90.57	0.00e+00	2792.00
IUUC-Mmr-060886	Microcebus murinus	99.31	0.00e+00	3018.00
IUUC-Mdo-062872	Monodelphis domestica	96.99	0.00e+00	2695.00
IUUC-Mmu-063672	Mus musculus	96.20	0.00e+00	2814.00
IUUC-Mpu-066692	Mustela putorius furo	97.54	0.00e+00	2912.00
IUUC-Mlu-067785	Myotis lucifugus	97.17	0.00e+00	2897.00
IUUC-Ont-072418	Oreochromis niloticus	80.50	0.00e+00	2085.00
IUUC-Ocu-074177	Oryctolagus cuniculus	94.62	0.00e+00	2873.00
IUUC-Ola-086880	Oryzias latipes	79.21	0.00e+00	2137.00
IUUC-Oga-088970	Otolemur garnettii	99.04	0.00e+00	3011.00
IUUC-Oar-090422	Ovis aries	96.94	0.00e+00	2847.00
IUUC-Pan-092441	Papio anubis	97.86	0.00e+00	2918.00
IUUC-Psi-093530	Pelodiscus sinensis	87.98	0.00e+00	2744.00
IUUC-Ppa-095213	Physcomitrella patens	41.66	0.00e+00	717.00
IUUC-Pfo-097530	Poecilia formosa	78.23	0.00e+00	2081.00
IUUC-Pab-097959	Pongo abelii	97.81	0.00e+00	2922.00
IUUC-Pva-103186	Pteropus vampyrus	98.82	0.00e+00	2962.00
IUUC-Rno-105692	Rattus norvegicus	95.41	0.00e+00	2818.00
IUUC-Ssc-115295	Sus scrofa	97.22	0.00e+00	2878.00
IUUC-Tgu-117484	Taeniopygia guttata	88.71	0.00e+00	2768.00
IUUC-Tru-118745	Takifugu rubripes	75.95	0.00e+00	2477.00
IUUC-Tsy-119261	Tarsius syrichta	88.82	0.00e+00	2089.00
IUUC-Tni-120764	Tetraodon nigroviridis	78.97	0.00e+00	2369.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence