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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046517
Ensembl Protein ID ENSP00000323183.4
UniProt Accession Q8N680; A8K7C7; Q5SZ81; Q9P245; ZBTB2_HUMAN
Genbank Protein ID BAF84631.1; CAI13589.1; EAW47751.1; AAH20172.1; BAA96007.1
Protein Name Zinc finger and BTB domain-containing protein 2
Genbank Nucleotide ID AK291942; AL590413; CH471051; BC020172; AB040916
Gene Name ZBTB2; KIAA1483; ZNF437
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000181472.4 ENST00000325144.4 ENSP00000323183.4
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbcircBaseCircNetmiRTarBase
microRNATRANSFACTargetScanRepTar
miRNAMapSomamiRmiRcodeRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Disease-associated Variation
GWASdbOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
HPRDPhospho.ELMUniProtPHOSIDA
BioGRID
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB 9.50e-12 46.8 24 85
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_Other: BTB
   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik..dvqpevfrallkFlYtgkl 65
           +D+++ +g+++f+ahk+vLa+ S +F+ lf ++ +e     +v +k  d+qp+ f+ ll+ +Ytgk+
   Q: 24   CDCTVAIGDVYFKAHKSVLASFSNYFKMLFVHQTSE-----CVRLKptDIQPDIFSYLLHLMYTGKM 85
           8*****************************998777.....58888879****************96 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MDLANHGLIL LQQLNAQREF GFLCDCTVAI GDVYFKAHKS VLASFSNYFK MLFVHQTSEC 60
VRLKPTDIQP DIFSYLLHLM YTGKMAPQLI DPVRLEQGIK FLHAYPLIQE ASLASQGAFS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046517|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ACCGACCGCG GCGGCAGCAG CAGCAGCAGC AGCGAGAGGC AGAGGCGGCG GCGGCGGGGA 60
GGACAGCACG GCCGAGGCTG CCCAGAGGCG CCTCCTCCAC ACCCCCCGCC GCAGCAGCAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046517|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-1017--Isopeptide bond
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0832--Ubl conjugation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR000210--BTB/POZ_dom
IPR004039--Rubredoxin-type_fold
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2
Pfam

PF00651--BTB
SMART

SM00225--BTB
SM00355--ZnF_C2H2
Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0046872--F:metal ion binding
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
KEGG hsa:57621
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001278 Ailuropoda melanoleuca 98.25 0.00e+00 1007.00
IUUC-Apl-004154 Anas platyrhynchos 88.72 0.00e+00 925.00
IUUC-Aca-004809 Anolis carolinensis 85.41 0.00e+00 844.00
IUUC-Ame-011189 Astyanax mexicanus 51.99 2.00e-145 509.00
IUUC-Bta-012488 Bos taurus 96.50 0.00e+00 979.00
IUUC-Cja-019536 Callithrix jacchus 99.61 0.00e+00 1022.00
IUUC-Cfa-020338 Canis familiaris 97.28 0.00e+00 997.00
IUUC-Cpo-021435 Cavia porcellus 95.72 0.00e+00 985.00
IUUC-Csa-023553 Chlorocebus sabaeus 99.22 0.00e+00 1016.00
IUUC-Cho-024746 Choloepus hoffmanni 95.42 0.00e+00 746.00
IUUC-Dre-028333 Danio rerio 53.02 2.00e-143 502.00
IUUC-Dno-029275 Dasypus novemcinctus 87.96 0.00e+00 880.00
IUUC-Dor-030356 Dipodomys ordii 93.19 0.00e+00 946.00
IUUC-Ete-032667 Echinops telfairi 92.05 0.00e+00 942.00
IUUC-Eca-033847 Equus caballus 97.47 0.00e+00 1000.00
IUUC-Eeu-035174 Erinaceus europaeus 80.86 7.00e-128 451.00
IUUC-Fca-035756 Felis catus 98.05 0.00e+00 1004.00
IUUC-Fal-037515 Ficedula albicollis 89.49 0.00e+00 926.00
IUUC-Gmo-039295 Gadus morhua 54.47 1.00e-145 509.00
IUUC-Gga-040413 Gallus gallus 89.11 0.00e+00 947.00
IUUC-Gac-041532 Gasterosteus aculeatus 55.27 2.00e-147 515.00
IUUC-Ggo-045148 Gorilla gorilla 99.81 0.00e+00 1023.00
IUUC-Itr-047943 Ictidomys tridecemlineatus 98.83 0.00e+00 1016.00
IUUC-Lch-049716 Latimeria chalumnae 71.71 0.00e+00 720.00
IUUC-Loc-052014 Lepisosteus oculatus 58.05 1.00e-168 586.00
IUUC-Laf-053602 Loxodonta africana 96.89 0.00e+00 1008.00
IUUC-Mcc-054967 Macaca mulatta 99.22 0.00e+00 1016.00
IUUC-Meu-056266 Macropus eugenii 90.47 0.00e+00 917.00
IUUC-Mga-059727 Meleagris gallopavo 88.72 0.00e+00 943.00
IUUC-Mdo-062662 Monodelphis domestica 95.33 0.00e+00 979.00
IUUC-Mmu-063728 Mus musculus 94.94 0.00e+00 978.00
IUUC-Mpu-066487 Mustela putorius furo 95.72 0.00e+00 979.00
IUUC-Mlu-067984 Myotis lucifugus 95.53 0.00e+00 996.00
IUUC-Nle-069536 Nomascus leucogenys 99.42 0.00e+00 1017.00
IUUC-Opr-071003 Ochotona princeps 95.14 0.00e+00 977.00
IUUC-Ont-072185 Oreochromis niloticus 57.20 3.00e-151 528.00
IUUC-Oan-073716 Ornithorhynchus anatinus 92.41 0.00e+00 942.00
IUUC-Ocu-073811 Oryctolagus cuniculus 98.64 0.00e+00 1013.00
IUUC-Ola-086731 Oryzias latipes 54.30 2.00e-147 515.00
IUUC-Oga-088649 Otolemur garnettii 97.86 0.00e+00 1007.00
IUUC-Oar-089982 Ovis aries 96.30 0.00e+00 977.00
IUUC-Ptr-090804 Pan troglodytes 99.61 0.00e+00 1023.00
IUUC-Psi-093460 Pelodiscus sinensis 87.16 0.00e+00 896.00
IUUC-Pma-094392 Petromyzon marinus 81.56 2.00e-68 253.00
IUUC-Pfo-096124 Poecilia formosa 55.24 6.00e-150 524.00
IUUC-Pab-097942 Pongo abelii 100.00 0.00e+00 1025.00
IUUC-Pca-100928 Procavia capensis 95.53 0.00e+00 995.00
IUUC-Rno-105175 Rattus norvegicus 94.75 0.00e+00 977.00
IUUC-Sha-106775 Sarcophilus harrisii 94.75 0.00e+00 975.00
IUUC-Ssc-115366 Sus scrofa 96.11 0.00e+00 995.00
IUUC-Tgu-116558 Taeniopygia guttata 89.49 0.00e+00 927.00
IUUC-Tru-117657 Takifugu rubripes 53.63 6.00e-143 500.00
IUUC-Tni-119687 Tetraodon nigroviridis 58.00 2.00e-155 541.00
IUUC-Ttr-128395 Tursiops truncatus 93.97 0.00e+00 967.00
IUUC-Xtr-132095 Xenopus tropicalis 78.60 0.00e+00 838.00
IUUC-Xma-134276 Xiphophorus maculatus 55.65 6.00e-149 520.00
Created Date 25-Jun-2017

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