iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106576

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01072603

Gene Name

FBXW8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000004192.1	ENSSHAT00000004823.1	ENSSHAP00000004775.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-12	47.9	370	402

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 6    vtclaf..sd.tllvsGsdDgtikvWDlrtgvl 35
            tc+++  s  +llv+G+ D  ++v+Dlr+ ++
   Q: 370  FTCVNLrnSPpHLLVTGNKDRRVRVYDLRSSTS 402
           589***96225889**************98765 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MAGAGLEEFR RRWREELAQR EGPAKRRLPP GPEWDERRRC ENEINEIPFF DIQLPYELAL 60
KIFQYLGRTE LGRCAQVSRM WKVLAEDEVL WYRLCQQEGY LPDTSISDCS CWKLVFQESR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGGGG CCGGTCTGGA GGAGTTCCGC CGGCGCTGGC GGGAGGAGCT GGCTCAGCGA 60
GAGGGGCCGG CCAAGCGACG GCTGCCCCCG GGACCCGAGT GGGATGAACG GCGGCNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:1990393--C:3M complex
GO:0031467--C:Cul7-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0048471--C:perinuclear region of cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008283--P:cell proliferation
GO:0007030--P:Golgi organization
GO:0060716--P:labyrinthine layer blood vessel development
GO:0050775--P:positive regulation of dendrite morphogenesis
GO:0060712--P:spongiotrophoblast layer development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001274	Ailuropoda melanoleuca	65.96	0.00e+00	728.00
IUUC-Apl-003239	Anas platyrhynchos	81.01	0.00e+00	860.00
IUUC-Aca-004756	Anolis carolinensis	74.63	3.00e-179	620.00
IUUC-Ame-011198	Astyanax mexicanus	56.99	1.00e-61	229.00
IUUC-Bta-012430	Bos taurus	43.69	5.00e-108	384.00
IUUC-Cja-019131	Callithrix jacchus	62.48	0.00e+00	651.00
IUUC-Cfa-021022	Canis familiaris	68.98	0.00e+00	726.00
IUUC-Cpo-021898	Cavia porcellus	66.87	0.00e+00	715.00
IUUC-Csa-023452	Chlorocebus sabaeus	63.87	0.00e+00	670.00
IUUC-Cho-024759	Choloepus hoffmanni	57.88	3.00e-174	604.00
IUUC-Dre-028123	Danio rerio	58.20	4.00e-176	611.00
IUUC-Dno-029045	Dasypus novemcinctus	69.28	0.00e+00	679.00
IUUC-Dor-030433	Dipodomys ordii	65.69	5.00e-166	577.00
IUUC-Ete-032465	Echinops telfairi	66.83	3.00e-171	594.00
IUUC-Eca-034134	Equus caballus	68.83	0.00e+00	732.00
IUUC-Eeu-035047	Erinaceus europaeus	60.45	0.00e+00	630.00
IUUC-Fca-036574	Felis catus	68.15	0.00e+00	724.00
IUUC-Fal-037665	Ficedula albicollis	73.94	0.00e+00	755.00
IUUC-Gmo-038988	Gadus morhua	69.47	2.00e-76	278.00
IUUC-Gga-040711	Gallus gallus	80.61	0.00e+00	854.00
IUUC-Gac-041675	Gasterosteus aculeatus	69.47	6.00e-79	286.00
IUUC-Ggo-045331	Gorilla gorilla	63.93	0.00e+00	672.00
IUUC-Hsa-046240	Homo sapiens	64.27	0.00e+00	677.00
IUUC-Itr-048412	Ictidomys tridecemlineatus	67.41	0.00e+00	696.00
IUUC-Loc-052631	Lepisosteus oculatus	67.55	0.00e+00	709.00
IUUC-Laf-054127	Loxodonta africana	62.94	9.00e-49	185.00
IUUC-Mcc-055083	Macaca mulatta	64.07	0.00e+00	674.00
IUUC-Mga-060113	Meleagris gallopavo	79.64	0.00e+00	847.00
IUUC-Mmr-061780	Microcebus murinus	66.07	0.00e+00	706.00
IUUC-Mdo-063066	Monodelphis domestica	95.95	0.00e+00	995.00
IUUC-Mmu-063524	Mus musculus	62.85	0.00e+00	661.00
IUUC-Mpu-066913	Mustela putorius furo	67.40	0.00e+00	716.00
IUUC-Mlu-067924	Myotis lucifugus	64.62	0.00e+00	692.00
IUUC-Nle-069558	Nomascus leucogenys	64.50	0.00e+00	638.00
IUUC-Opr-070506	Ochotona princeps	67.55	0.00e+00	707.00
IUUC-Ont-071514	Oreochromis niloticus	59.24	2.00e-175	608.00
IUUC-Ocu-074477	Oryctolagus cuniculus	67.49	0.00e+00	701.00
IUUC-Oba-075381	Oryza barthii	41.18	9.00e-08	51.20
IUUC-Obr-076074	Oryza brachyantha	39.71	2.00e-07	50.10
IUUC-Olo-080372	Oryza longistaminata	41.18	9.00e-08	50.80
IUUC-Osa-086065	Oryza sativa	41.18	9.00e-08	51.20
IUUC-Ola-087416	Oryzias latipes	57.92	5.00e-172	597.00
IUUC-Oga-088643	Otolemur garnettii	67.27	0.00e+00	726.00
IUUC-Oar-090172	Ovis aries	67.68	0.00e+00	717.00
IUUC-Ptr-090870	Pan troglodytes	64.27	0.00e+00	677.00
IUUC-Pan-092017	Papio anubis	63.67	0.00e+00	666.00
IUUC-Psi-093794	Pelodiscus sinensis	83.87	0.00e+00	879.00
IUUC-Pfo-096192	Poecilia formosa	61.04	3.00e-180	624.00
IUUC-Pab-097882	Pongo abelii	62.79	0.00e+00	668.00
IUUC-Pca-100902	Procavia capensis	68.57	3.00e-99	355.00
IUUC-Pva-103139	Pteropus vampyrus	68.06	0.00e+00	733.00
IUUC-Rno-105798	Rattus norvegicus	62.65	0.00e+00	676.00
IUUC-Ssc-115923	Sus scrofa	64.23	0.00e+00	674.00
IUUC-Tgu-116667	Taeniopygia guttata	69.07	1.00e-153	535.00
IUUC-Tru-118323	Takifugu rubripes	56.83	9.00e-168	583.00
IUUC-Tsy-118818	Tarsius syrichta	46.62	1.00e-110	392.00
IUUC-Tni-120438	Tetraodon nigroviridis	56.91	3.00e-162	565.00
IUUC-Tbe-127784	Tupaia belangeri	69.71	6.00e-86	310.00
IUUC-Ttr-128288	Tursiops truncatus	60.40	6.00e-180	623.00
IUUC-Vpa-130307	Vicugna pacos	64.24	7.00e-175	606.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence