iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004639

UUCD1 version

UUC-AnC-00630

Ensembl Protein ID

ENSACAP00000007271.3

UniProt Accession

G1KGK6; G1KGK6_ANOCA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000007418.3	ENSACAT00000007427.3	ENSACAP00000007271.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	3.10e-15	55.7	109	156

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
           +++ +++s++ SLqhLCR++Ir++++++++   ++LPLPk L++Y++++ y
   Q: 109  LYPVSRFSNVKSLQHLCRFRIRQLVRIDHI---PELPLPKPLISYIRKFYY 156
           567899*********************998...*************99976 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

CGWYWGPMNW EDAEMKLKGK PDGSFLVRDS SDPRYILSLS FRSQGITHHT RMEHYRGTFS 60
LWCHPKFEDR CQSVVEFIKR AIMHSKNGKF LYFLRSRVPG LPPTPVQLLY PVSRFSNVKS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATGATTTAA AAGTCATCTT TGTCCAATGT GCCGGTTCTT CCTTTTCTGT GCCAAGTCAA 60
AGAGTAGGTG CTGGATCCAA ATGTTCCTAA AAATGTTCTA TTGAAACAAG TTGATAGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028423--SOCS7
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001668	Ailuropoda melanoleuca	97.28	2.00e-107	382.00
IUUC-Apl-003277	Anas platyrhynchos	89.73	1.00e-71	261.00
IUUC-Ame-011301	Astyanax mexicanus	86.41	1.00e-96	346.00
IUUC-Bta-013483	Bos taurus	98.33	4.00e-106	378.00
IUUC-Cel-018643	Caenorhabditis elegans	30.47	1.00e-11	62.80
IUUC-Cja-019765	Callithrix jacchus	97.28	8.00e-107	379.00
IUUC-Cfa-020109	Canis familiaris	97.28	5.00e-107	381.00
IUUC-Cpo-021555	Cavia porcellus	98.37	3.00e-108	385.00
IUUC-Csa-023580	Chlorocebus sabaeus	97.28	5.00e-107	381.00
IUUC-Cho-024431	Choloepus hoffmanni	96.06	1.00e-69	256.00
IUUC-Dre-028183	Danio rerio	87.50	1.00e-98	353.00
IUUC-Dno-028858	Dasypus novemcinctus	97.28	5.00e-107	381.00
IUUC-Dor-031071	Dipodomys ordii	64.67	2.00e-61	228.00
IUUC-Dme-031876	Drosophila melanogaster	48.77	5.00e-39	156.00
IUUC-Ete-032928	Echinops telfairi	98.85	2.00e-48	186.00
IUUC-Eca-033250	Equus caballus	89.45	4.00e-104	370.00
IUUC-Eeu-034946	Erinaceus europaeus	94.05	3.00e-42	166.00
IUUC-Fca-036589	Felis catus	97.83	7.00e-108	384.00
IUUC-Fal-037316	Ficedula albicollis	93.48	7.00e-102	362.00
IUUC-Gmo-038552	Gadus morhua	92.23	7.00e-53	198.00
IUUC-Gga-041248	Gallus gallus	97.28	2.00e-106	377.00
IUUC-Gac-041469	Gasterosteus aculeatus	82.26	2.00e-56	211.00
IUUC-Ggo-045282	Gorilla gorilla	97.28	7.00e-107	379.00
IUUC-Hsa-045926	Homo sapiens	97.28	4.00e-107	381.00
IUUC-Itr-048411	Ictidomys tridecemlineatus	100.00	1.00e-58	220.00
IUUC-Lch-049768	Latimeria chalumnae	91.30	6.00e-101	360.00
IUUC-Loc-051949	Lepisosteus oculatus	89.67	1.00e-99	357.00
IUUC-Laf-053410	Loxodonta africana	96.74	4.00e-107	381.00
IUUC-Mcc-054605	Macaca mulatta	97.28	1.00e-106	380.00
IUUC-Meu-056773	Macropus eugenii	95.28	2.00e-68	252.00
IUUC-Mmr-060927	Microcebus murinus	97.28	1.00e-107	383.00
IUUC-Mdo-061892	Monodelphis domestica	96.74	1.00e-106	380.00
IUUC-Mmu-064246	Mus musculus	97.28	5.00e-107	381.00
IUUC-Mpu-065995	Mustela putorius furo	97.28	2.00e-107	382.00
IUUC-Mlu-067526	Myotis lucifugus	97.28	5.00e-107	381.00
IUUC-Nle-069317	Nomascus leucogenys	99.31	9.00e-87	313.00
IUUC-Ont-072258	Oreochromis niloticus	87.50	9.00e-98	350.00
IUUC-Oan-073703	Ornithorhynchus anatinus	77.91	7.00e-36	140.00
IUUC-Ocu-074577	Oryctolagus cuniculus	97.28	3.00e-107	382.00
IUUC-Oga-088426	Otolemur garnettii	97.28	6.00e-107	381.00
IUUC-Oar-089407	Ovis aries	98.33	3.00e-106	378.00
IUUC-Ptr-091327	Pan troglodytes	97.28	2.00e-107	381.00
IUUC-Pan-092064	Papio anubis	97.28	5.00e-107	381.00
IUUC-Psi-093834	Pelodiscus sinensis	96.74	3.00e-106	377.00
IUUC-Pfo-097100	Poecilia formosa	84.78	3.00e-94	339.00
IUUC-Pab-097695	Pongo abelii	97.28	7.00e-107	380.00
IUUC-Pca-100569	Procavia capensis	96.20	4.00e-104	371.00
IUUC-Pva-102784	Pteropus vampyrus	97.28	4.00e-107	381.00
IUUC-Ptt-103775	Puccinia triticina	35.56	5.30e-01	29.60
IUUC-Rno-105485	Rattus norvegicus	97.28	5.00e-107	381.00
IUUC-Sha-106720	Sarcophilus harrisii	96.74	2.00e-106	379.00
IUUC-Sar-112975	Sorex araneus	72.83	2.00e-73	268.00
IUUC-Ssc-116369	Sus scrofa	97.78	2.00e-105	376.00
IUUC-Tgu-116867	Taeniopygia guttata	96.74	5.00e-106	377.00
IUUC-Tru-117562	Takifugu rubripes	87.36	1.00e-90	327.00
IUUC-Tsy-118999	Tarsius syrichta	96.97	6.00e-93	333.00
IUUC-Tni-120793	Tetraodon nigroviridis	86.02	9.00e-96	343.00
IUUC-Tbe-127671	Tupaia belangeri	96.74	8.00e-106	377.00
IUUC-Ttr-128491	Tursiops truncatus	97.66	2.00e-72	266.00
IUUC-Vpa-130104	Vicugna pacos	97.22	9.00e-103	367.00
IUUC-Xtr-132507	Xenopus tropicalis	92.39	6.00e-102	363.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence