iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000004736.1	ENSONIT00000005968.1	ENSONIP00000005964.1
ENSONIG00000004736.1	ENSONIT00000005969.1	ENSONIP00000005965.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.80e-18	66.6	793	844

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           ++ yd+++ ++ eL+l++Gdvv++   ++  +gW++g  e +g+ G fP+ +ve+
   Q: 793  IARYDFSSRDTRELSLQEGDVVKIY-TKSGANGWWRG--EVNGRVGWFPSTYVEE 844
           678*********************9.99*********..9*************96 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MEYWRQCALW LINCKVLPAN HRVTWDSAQV FDLAQTLRDG VLLCHLLNNL RPQTINLKEI 60
NLRPQMSQFL CLKNIRTFLA ACSDVFGMKK SELFEAFDLF DVRDFGKVMD TLSKLSHTVI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGTATGTGT GTGTATTTAG TGTAATGTGA CTGTATGCTT TATGTGGTTA TGTCTTGCAT 60
TGCAATAGAC GCATCTCCAC GAGCCTATGG GTGGCAAGCG GAAGAGGTGA AGAGCTGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc

Interpro

IPR022613--CAMSAP_CH
IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain
IPR013315--Spectrin_alpha_SH3

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF11971--CAMSAP_CH
PF00169--PH
PF00621--RhoGEF
PF00017--SH2
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR01887--SPECTRNALPHA

SMART

SM00109--C1
SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001362	Ailuropoda melanoleuca	72.46	0.00e+00	1196.00
IUUC-Apl-003734	Anas platyrhynchos	71.99	0.00e+00	1105.00
IUUC-Aca-004477	Anolis carolinensis	70.05	0.00e+00	1168.00
IUUC-Ame-011279	Astyanax mexicanus	71.82	0.00e+00	1171.00
IUUC-Bta-012722	Bos taurus	71.39	0.00e+00	1177.00
IUUC-Cja-018941	Callithrix jacchus	72.04	0.00e+00	1176.00
IUUC-Cfa-020266	Canis familiaris	70.49	0.00e+00	1033.00
IUUC-Cpo-021966	Cavia porcellus	68.72	0.00e+00	998.00
IUUC-Csa-023892	Chlorocebus sabaeus	70.29	0.00e+00	1066.00
IUUC-Dno-029474	Dasypus novemcinctus	71.99	0.00e+00	1193.00
IUUC-Eca-033961	Equus caballus	70.49	0.00e+00	1059.00
IUUC-Eeu-034719	Erinaceus europaeus	56.22	1.00e-164	573.00
IUUC-Fca-036572	Felis catus	71.58	0.00e+00	1154.00
IUUC-Fal-036802	Ficedula albicollis	71.18	0.00e+00	1222.00
IUUC-Gmo-039409	Gadus morhua	80.66	0.00e+00	1326.00
IUUC-Gga-040884	Gallus gallus	72.47	0.00e+00	1222.00
IUUC-Gac-041395	Gasterosteus aculeatus	88.84	0.00e+00	1502.00
IUUC-Ggo-044460	Gorilla gorilla	68.59	0.00e+00	996.00
IUUC-Hsa-046099	Homo sapiens	69.57	0.00e+00	1170.00
IUUC-Itr-048144	Ictidomys tridecemlineatus	67.01	0.00e+00	1003.00
IUUC-Lch-049650	Latimeria chalumnae	77.99	5.00e-101	360.00
IUUC-Loc-052487	Lepisosteus oculatus	79.06	0.00e+00	1333.00
IUUC-Laf-054564	Loxodonta africana	71.63	0.00e+00	1185.00
IUUC-Mcc-054622	Macaca mulatta	69.45	0.00e+00	1172.00
IUUC-Meu-056680	Macropus eugenii	65.60	0.00e+00	1088.00
IUUC-Mga-060013	Meleagris gallopavo	71.39	0.00e+00	1186.00
IUUC-Mmr-061251	Microcebus murinus	68.31	0.00e+00	1189.00
IUUC-Mdo-061875	Monodelphis domestica	71.16	0.00e+00	1192.00
IUUC-Mmu-063735	Mus musculus	71.99	0.00e+00	1222.00
IUUC-Mpu-065856	Mustela putorius furo	72.10	0.00e+00	1191.00
IUUC-Mlu-068108	Myotis lucifugus	68.73	0.00e+00	1140.00
IUUC-Nle-069863	Nomascus leucogenys	68.43	0.00e+00	1139.00
IUUC-Opr-070372	Ochotona princeps	61.50	0.00e+00	744.00
IUUC-Ocu-074194	Oryctolagus cuniculus	71.87	0.00e+00	1202.00
IUUC-Ola-086336	Oryzias latipes	87.04	0.00e+00	1485.00
IUUC-Oar-089272	Ovis aries	71.51	0.00e+00	1216.00
IUUC-Ptr-090652	Pan troglodytes	70.21	0.00e+00	1174.00
IUUC-Pan-092550	Papio anubis	67.60	0.00e+00	1012.00
IUUC-Psi-093784	Pelodiscus sinensis	68.39	0.00e+00	1038.00
IUUC-Pfo-097308	Poecilia formosa	85.24	0.00e+00	1470.00
IUUC-Pab-098698	Pongo abelii	69.98	0.00e+00	1174.00
IUUC-Pva-102262	Pteropus vampyrus	71.50	0.00e+00	1142.00
IUUC-Rno-105421	Rattus norvegicus	72.10	0.00e+00	1225.00
IUUC-Sha-107325	Sarcophilus harrisii	71.39	0.00e+00	1205.00
IUUC-Sar-113456	Sorex araneus	67.85	0.00e+00	1135.00
IUUC-Tgu-116595	Taeniopygia guttata	71.43	0.00e+00	1183.00
IUUC-Tru-118577	Takifugu rubripes	81.01	0.00e+00	1310.00
IUUC-Tni-119951	Tetraodon nigroviridis	83.68	0.00e+00	1383.00
IUUC-Tur-126172	Triticum urartu	25.81	3.30e-01	30.00
IUUC-Tbe-127995	Tupaia belangeri	66.25	2.00e-134	473.00
IUUC-Ttr-128281	Tursiops truncatus	71.99	0.00e+00	1186.00
IUUC-Xtr-132427	Xenopus tropicalis	65.29	0.00e+00	1149.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence