iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mac-064989

Ensembl Protein ID

GSMUA_Achr6P12600_001

UniProt Accession

M0T6F8; M0T6F8_MUSAM

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GSMUA_Achr6G12600_001	GSMUA_Achr6T12600_001	GSMUA_Achr6P12600_001

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.60e-97	327.1	836	1181

Active Site

Position(s)	Description	Evidence
1149	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqd 84
           +lk+ ++v+f +     E+gld+gG+++efl+ lsk  +np+ glf ++++++++l pn ++ l + + +++ eflGr++gkal++
   Q: 836  KLKSCINVSFINesglpEAGLDYGGLSKEFLTDLSKSGFNPEFGLFSQTSTSDSSLIPNMAARLLD-NGIEMIEFLGRVVGKALYE 920
           5788999*****8888889*******************************************9976.******************* PP
   S: 85   grlldlplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNk 170
           g ll++ +s +f ++llg+   l++l+++d+ely++l ++k+  + d+++l+ld+t  v e+i+g++ ++eLkpgG ni+VtneNk
   Q: 921  GILLEYSFSLVFVQKLLGRYSFLDELSTLDSELYRNLIYVKHF-DGDVTDLALDFT--VAEDICGKRIVTELKPGGTNISVTNENK 1003
           ********************999******************99.678888766555..5699************************ PP
   S: 171  eeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevlee 255
            +Yv+++++y+l+++i    +af++G+ ++i++++lslF+++e+++l++G  +++dv+dl+++tky ggy+e+s++++ Fwev+++
   Q: 1004 LQYVHAMADYKLNRQILPFANAFYRGLIDLISPSWLSLFNANEFNQLLSGGiNDFDVDDLRSNTKYSGGYSETSRTVKLFWEVVKG 1089
           ************************************************************************************** PP
   S: 256  fsseerkafLqFvTgssrlPlgGfaelkprlfvirk...........dasd.drlPssnTCfnyLkLPeYsskeilkekLlyAiee 329
           f++ er+++L+FvT++sr+Pl Gf+ l+p  f+i+k            ++d drlPs++TC+n+LkLP+Y+  ++l++kLlyAi++
   Q: 1090 FKAIERCMLLKFVTSCSRAPLLGFKHLQPA-FTIHKvacdlplwatlGGQDvDRLPSASTCYNTLKLPTYKRSSTLRNKLLYAISS 1174
           ****************************88.999999*********955555********************************** PP
   S: 330  tkgFels 336
           ++gFels
   Q: 1175 NTGFELS 1181
           ****985 PP

Organism

Musa acuminata

Protein Sequence
(Fasta)

MSGPPQQRQV STSLLHQSPI ISPSRATFSK EFLGRRPLIP SFGLLAKLAH ERELRSYQRR 60
ASAAALFIQR VWRRYIVIKK VSEQLQEEWE ALADHYDDHM TSGWISNNFL RPFLFFATRS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGGGAC CTCCGCAGCA ACGGCAGGTA AGTACCTCCC TCCTGCACCA GTCTCCGATT 60
ATTTCCCCGA GTCGTGCGAC TTTCTCGAAA GAGTTCTTGG GGCGCCGACC TCTGATCCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR027401--Myosin-like_IQ_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	63.11	0.00e+00	1215.00
IUUC-Aml-002107	Ailuropoda melanoleuca	39.36	7.00e-107	381.00
IUUC-Atr-003017	Amborella trichopoda	57.20	0.00e+00	1275.00
IUUC-Apl-003328	Anas platyrhynchos	39.36	6.00e-108	385.00
IUUC-Aly-005794	Arabidopsis lyrata	53.28	0.00e+00	1120.00
IUUC-Ath-007269	Arabidopsis thaliana	52.89	0.00e+00	1154.00
IUUC-Afl-008398	Aspergillus flavus	39.54	1.00e-74	274.00
IUUC-Afu-008937	Aspergillus fumigatus	40.33	1.00e-73	271.00
IUUC-Aor-009940	Aspergillus oryzae	39.54	1.00e-74	274.00
IUUC-Bta-013547	Bos taurus	39.36	2.00e-107	383.00
IUUC-Bdi-014502	Brachypodium distachyon	62.41	0.00e+00	1320.00
IUUC-Bol-015093	Brassica oleracea	53.48	0.00e+00	1128.00
IUUC-Bra-016722	Brassica rapa	53.77	0.00e+00	1146.00
IUUC-Cel-018447	Caenorhabditis elegans	37.88	6.00e-94	338.00
IUUC-Cja-019855	Callithrix jacchus	39.36	3.00e-107	382.00
IUUC-Cfa-020066	Canis familiaris	38.29	4.00e-101	362.00
IUUC-Cpo-021504	Cavia porcellus	39.54	1.00e-108	387.00
IUUC-Cre-022673	Chlamydomonas reinhardtii	47.64	4.00e-107	382.00
IUUC-Csa-023579	Chlorocebus sabaeus	39.54	6.00e-108	385.00
IUUC-Csv-026016	Ciona savignyi	37.74	6.00e-104	371.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	39.01	5.00e-82	299.00
IUUC-Cne-026841	Cryptococcus neoformans	35.05	4.00e-82	299.00
IUUC-Dre-028271	Danio rerio	39.47	2.00e-109	390.00
IUUC-Dno-029054	Dasypus novemcinctus	39.18	6.00e-107	381.00
IUUC-Dor-030938	Dipodomys ordii	37.46	4.00e-101	362.00
IUUC-Dme-031602	Drosophila melanogaster	38.38	4.00e-109	389.00
IUUC-Eca-034411	Equus caballus	39.54	5.00e-108	385.00
IUUC-Eeu-035201	Erinaceus europaeus	33.26	1.00e-69	258.00
IUUC-Fca-036594	Felis catus	38.83	9.00e-106	377.00
IUUC-Fal-037317	Ficedula albicollis	39.36	7.00e-108	384.00
IUUC-Fox-037788	Fusarium oxysporum	32.69	2.00e-81	296.00
IUUC-Gmo-039412	Gadus morhua	39.01	1.00e-107	384.00
IUUC-Ggr-039941	Gaeumannomyces graminis	36.97	4.00e-77	283.00
IUUC-Gga-040149	Gallus gallus	39.36	5.00e-108	385.00
IUUC-Gma-042728	Glycine max	56.20	0.00e+00	1218.00
IUUC-Ggo-045279	Gorilla gorilla	39.36	3.00e-107	382.00
IUUC-Hsa-045660	Homo sapiens	39.54	9.00e-108	384.00
IUUC-Hvu-047102	Hordeum vulgare	62.44	0.00e+00	1205.00
IUUC-Lch-050664	Latimeria chalumnae	39.54	1.00e-108	387.00
IUUC-Lpe-050755	Leersia perrieri	57.03	0.00e+00	1119.00
IUUC-Loc-052791	Lepisosteus oculatus	39.93	8.00e-109	387.00
IUUC-Laf-053902	Loxodonta africana	39.25	3.00e-107	382.00
IUUC-Mcc-054730	Macaca mulatta	39.54	6.00e-108	385.00
IUUC-Meu-056527	Macropus eugenii	33.93	2.00e-84	306.00
IUUC-Mor-057021	Magnaporthe oryzae	38.30	3.00e-71	263.00
IUUC-Mpo-057570	Magnaporthe poae	36.19	4.00e-74	273.00
IUUC-Mtr-057671	Medicago truncatula	57.06	0.00e+00	1235.00
IUUC-Mga-059260	Meleagris gallopavo	39.36	7.00e-108	384.00
IUUC-Mmr-060804	Microcebus murinus	39.36	1.00e-106	380.00
IUUC-Mdo-062575	Monodelphis domestica	38.30	1.00e-104	374.00
IUUC-Mmu-063636	Mus musculus	38.69	2.00e-106	380.00
IUUC-Mlu-067952	Myotis lucifugus	39.36	3.00e-107	382.00
IUUC-Ncr-068869	Neurospora crassa	35.92	3.00e-84	306.00
IUUC-Nle-069153	Nomascus leucogenys	39.54	7.00e-108	384.00
IUUC-Opr-070554	Ochotona princeps	39.01	2.00e-105	376.00
IUUC-Ont-071372	Oreochromis niloticus	40.00	3.00e-110	392.00
IUUC-Ocu-074183	Oryctolagus cuniculus	39.12	2.00e-107	383.00
IUUC-Oba-075213	Oryza barthii	63.10	0.00e+00	1144.00
IUUC-Obr-076320	Oryza brachyantha	62.73	0.00e+00	1258.00
IUUC-Ogl-077093	Oryza glaberrima	62.05	0.00e+00	1285.00
IUUC-Ogu-078235	Oryza glumaepatula	59.19	0.00e+00	1171.00
IUUC-Oin-080058	Oryza indica	59.70	0.00e+00	1250.00
IUUC-Olo-080742	Oryza longistaminata	62.14	0.00e+00	1315.00
IUUC-Ome-081741	Oryza meridionalis	59.06	0.00e+00	1242.00
IUUC-Oni-082616	Oryza nivara	59.34	0.00e+00	1183.00
IUUC-Opu-083529	Oryza punctata	62.86	0.00e+00	1181.00
IUUC-Oru-085128	Oryza rufipogon	61.73	0.00e+00	1098.00
IUUC-Osa-085557	Oryza sativa	70.18	0.00e+00	985.00
IUUC-Ola-087337	Oryzias latipes	40.25	3.00e-110	392.00
IUUC-Olu-087902	Ostreococcus lucimarinus	43.60	4.00e-94	337.00
IUUC-Oga-088342	Otolemur garnettii	39.12	3.00e-105	376.00
IUUC-Ptr-091661	Pan troglodytes	39.18	8.00e-107	381.00
IUUC-Pan-092728	Papio anubis	39.29	3.00e-106	379.00
IUUC-Pma-094195	Petromyzon marinus	39.65	1.00e-111	397.00
IUUC-Ppa-095544	Physcomitrella patens	64.16	0.00e+00	744.00
IUUC-Pfo-097472	Poecilia formosa	40.00	3.00e-110	392.00
IUUC-Pab-098570	Pongo abelii	39.36	7.00e-107	381.00
IUUC-Pop-099058	Populus trichocarpa	51.07	0.00e+00	770.00
IUUC-Pca-100110	Procavia capensis	35.99	4.00e-94	339.00
IUUC-Ppe-101281	Prunus persica	55.83	0.00e+00	1256.00
IUUC-Rno-106028	Rattus norvegicus	38.14	1.00e-92	333.00
IUUC-Sce-106446	Saccharomyces cerevisiae	40.14	2.00e-70	260.00
IUUC-Sha-107331	Sarcophilus harrisii	38.48	2.00e-105	376.00
IUUC-Smo-109537	Selaginella moellendorffii	43.56	0.00e+00	787.00
IUUC-Sit-109811	Setaria italica	61.37	0.00e+00	1282.00
IUUC-Sly-111013	Solanum lycopersicum	54.53	0.00e+00	1170.00
IUUC-Sbi-114433	Sorghum bicolor	61.49	0.00e+00	1296.00
IUUC-Sre-115038	Sporisorium reilianum	44.69	4.00e-91	329.00
IUUC-Ssc-116103	Sus scrofa	39.36	5.00e-107	382.00
IUUC-Tgu-117275	Taeniopygia guttata	39.36	9.00e-108	384.00
IUUC-Tru-118681	Takifugu rubripes	39.82	5.00e-110	392.00
IUUC-Tni-120732	Tetraodon nigroviridis	41.89	4.00e-103	369.00
IUUC-Tca-121770	Theobroma cacao	56.95	0.00e+00	1190.00
IUUC-Tre-121892	Trichoderma reesei	40.84	5.00e-85	308.00
IUUC-Tae-124300	Triticum aestivum	85.51	1.00e-141	494.00
IUUC-Tur-126086	Triticum urartu	61.11	0.00e+00	1194.00
IUUC-Tbe-127461	Tupaia belangeri	36.36	5.00e-86	312.00
IUUC-Ttr-129269	Tursiops truncatus	39.54	2.00e-107	383.00
IUUC-Uma-129343	Ustilago maydis	43.72	8.00e-93	335.00
IUUC-Vda-129748	Verticillium dahliae	37.26	2.00e-72	267.00
IUUC-Vvi-131524	Vitis vinifera	58.31	0.00e+00	1271.00
IUUC-Xtr-132146	Xenopus tropicalis	39.18	3.00e-107	382.00
IUUC-Xma-133526	Xiphophorus maculatus	40.00	2.00e-110	393.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence