iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004238

UUCD1 version

UUC-AnC-00020

Ensembl Protein ID

ENSACAP00000011273.3

UniProt Accession

H9GHQ6; H9GHQ6_ANOCA

Protein Name

Uncharacterized protein

Gene Name

KLHL4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000011367.3	ENSACAT00000011509.3	ENSACAP00000011273.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.40e-19	69.4	181	248
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	4.30e-07	29.2	280	311

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dv+l+ g+ +++ah++vL+a+S++F a+f+++ +e k ++++++++v+p+++++l+++ Ytg l+++e
   Q: 181  CDVLLIAGDHKIPAHRLVLSAASDYFAAMFTNDVREAK-QEEIKMEGVDPDALKDLVRYAYTGILELKE 248
           8************************************9.************************999876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclgi++f+d+ +c+dL ++a+ ++  hF+
   Q: 280  PSNCLGIRSFGDAQGCTDLLQVAHVYTMEHFT 311
           89************************999996 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MSVSGKKEFD VKQILRLRWR WFSHPSQGST GTGGCLQQEG YEHRGTPVPG RLKSHSRDRN 60
GLKKNNSPIH HNLLAPVPAG PTPVPHRPVQ TWREDLIEHL QGTEEMPKEN EEKEDPNKNT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGATAAGGA ATGAAGCACG AGCCACTTCC ATCCCTGAAG TTGCAGCGGA AGATCCCTTA 60
GGATGCTCTC CGGCTAGGTT GCTTGCTTGC TTTATATATT GGAGAGCGCA GCTCTTGGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005815--C:microtubule organizing center
GO:0016567--P:protein ubiquitination

KEGG

acs:100558173

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001422	Ailuropoda melanoleuca	77.81	0.00e+00	1101.00
IUUC-Apl-004156	Anas platyrhynchos	94.72	0.00e+00	1092.00
IUUC-Afl-008653	Aspergillus flavus	29.49	5.70e-01	28.10
IUUC-Ame-011287	Astyanax mexicanus	72.09	0.00e+00	939.00
IUUC-Bta-013232	Bos taurus	76.90	0.00e+00	990.00
IUUC-Cja-018916	Callithrix jacchus	79.09	0.00e+00	1120.00
IUUC-Cfa-020972	Canis familiaris	82.52	0.00e+00	971.00
IUUC-Csa-023849	Chlorocebus sabaeus	80.75	0.00e+00	1177.00
IUUC-Dor-030708	Dipodomys ordii	73.40	0.00e+00	1046.00
IUUC-Ete-033156	Echinops telfairi	70.58	0.00e+00	687.00
IUUC-Eca-033542	Equus caballus	78.39	0.00e+00	1124.00
IUUC-Fal-036999	Ficedula albicollis	87.81	0.00e+00	1261.00
IUUC-Gmo-039532	Gadus morhua	83.86	0.00e+00	972.00
IUUC-Gga-040215	Gallus gallus	89.61	0.00e+00	1297.00
IUUC-Gac-041582	Gasterosteus aculeatus	85.26	0.00e+00	1005.00
IUUC-Ggo-045074	Gorilla gorilla	80.75	0.00e+00	1176.00
IUUC-Hsa-046486	Homo sapiens	80.28	0.00e+00	1143.00
IUUC-Lch-050265	Latimeria chalumnae	87.06	0.00e+00	1036.00
IUUC-Loc-052015	Lepisosteus oculatus	80.91	0.00e+00	1133.00
IUUC-Laf-053627	Loxodonta africana	79.64	0.00e+00	1164.00
IUUC-Mcc-055418	Macaca mulatta	81.16	0.00e+00	1182.00
IUUC-Meu-056859	Macropus eugenii	72.36	5.00e-139	487.00
IUUC-Mga-059582	Meleagris gallopavo	89.04	0.00e+00	1218.00
IUUC-Mmr-061648	Microcebus murinus	79.09	0.00e+00	1158.00
IUUC-Mdo-062785	Monodelphis domestica	89.30	0.00e+00	1019.00
IUUC-Mmu-063807	Mus musculus	76.70	0.00e+00	1114.00
IUUC-Mpu-066279	Mustela putorius furo	82.81	0.00e+00	968.00
IUUC-Mlu-067981	Myotis lucifugus	76.59	0.00e+00	1119.00
IUUC-Nle-070033	Nomascus leucogenys	80.23	0.00e+00	1141.00
IUUC-Ont-071932	Oreochromis niloticus	78.02	0.00e+00	1132.00
IUUC-Oba-075850	Oryza barthii	35.21	3.00e-03	35.40
IUUC-Oni-082714	Oryza nivara	35.21	5.00e-03	35.40
IUUC-Ola-087436	Oryzias latipes	76.49	0.00e+00	1093.00
IUUC-Oar-089952	Ovis aries	78.50	0.00e+00	1146.00
IUUC-Ptr-091649	Pan troglodytes	75.17	0.00e+00	1042.00
IUUC-Pan-091798	Papio anubis	81.02	0.00e+00	1182.00
IUUC-Psi-093728	Pelodiscus sinensis	87.40	0.00e+00	1269.00
IUUC-Pfo-096954	Poecilia formosa	78.04	0.00e+00	1110.00
IUUC-Pab-098461	Pongo abelii	80.19	0.00e+00	1160.00
IUUC-Pva-102458	Pteropus vampyrus	78.33	0.00e+00	1014.00
IUUC-Rno-105865	Rattus norvegicus	77.12	0.00e+00	1112.00
IUUC-Sha-107322	Sarcophilus harrisii	88.22	0.00e+00	1008.00
IUUC-Smo-109299	Selaginella moellendorffii	26.09	8.00e-16	79.00
IUUC-Ssc-116001	Sus scrofa	80.08	0.00e+00	1169.00
IUUC-Tgu-116994	Taeniopygia guttata	89.06	0.00e+00	1281.00
IUUC-Tru-117780	Takifugu rubripes	72.31	0.00e+00	1028.00
IUUC-Tni-120794	Tetraodon nigroviridis	75.44	0.00e+00	1049.00
IUUC-Tbe-128118	Tupaia belangeri	65.43	0.00e+00	809.00
IUUC-Vpa-130811	Vicugna pacos	74.61	0.00e+00	1051.00
IUUC-Xtr-132358	Xenopus tropicalis	82.39	0.00e+00	1208.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence