iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053627

UUCD1 version

UUC-LoA-00031

Ensembl Protein ID

ENSLAFP00000000702.3

UniProt Accession

G3SMG0; G3SMG0_LOXAF

Protein Name

Uncharacterized protein

Gene Name

KLHL4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000000845.3	ENSLAFT00000000845.3	ENSLAFP00000000702.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.10e-17	64.5	182	249
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.30e-06	27.7	281	311

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dv+l+ g+ +++ah++vL+a S++F a+f+++  e k +++v++++v+p +++ l+++ Ytg l+++e
   Q: 182  CDVLLIAGDLRIPAHRLVLSAVSDYFAAMFTNDVLEAK-QEEVKMEGVDPNALNSLVQYAYTGVLQLKE 249
           8************************************9.**************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Nclgi++f+d+ +c +L ++a++++  hF
   Q: 281  PSNCLGIRSFGDAQGCMELLKVAHKYTMEHF 311
           89************************98777 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MSVSGKKEFD VKQILRLRWR WFSHPSQGSP NTGSCLQQEG YEHRGTPVQG RLKSHSRDRS 60
GLKKSNSPGH HNILAPVPGP APAHQRALQN WQQQNLVEHL RANEDTPKTV TEENLFKEAC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAGTGT CTGGCAAGAA AGAGTTTGAT GTGAAACAGA TCCTAAGGCT ACGCTGGAGG 60
TGGTTTAGTC ATCCTTCTCA AGGTTCACCC AACACTGGAA GCTGCCTTCA GCAGGAAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005815--C:microtubule organizing center

KEGG

lav:100677747

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001422	Ailuropoda melanoleuca	89.70	0.00e+00	1275.00
IUUC-Apl-004156	Anas platyrhynchos	85.92	0.00e+00	1001.00
IUUC-Aca-004238	Anolis carolinensis	79.22	0.00e+00	1145.00
IUUC-Ame-011287	Astyanax mexicanus	70.77	0.00e+00	917.00
IUUC-Bta-013232	Bos taurus	88.47	0.00e+00	1146.00
IUUC-Cja-018916	Callithrix jacchus	89.56	0.00e+00	1280.00
IUUC-Cfa-020972	Canis familiaris	90.48	0.00e+00	1067.00
IUUC-Csa-023849	Chlorocebus sabaeus	90.39	0.00e+00	1326.00
IUUC-Dor-030708	Dipodomys ordii	82.98	0.00e+00	1180.00
IUUC-Ete-033156	Echinops telfairi	82.95	0.00e+00	832.00
IUUC-Eca-033542	Equus caballus	89.69	0.00e+00	1298.00
IUUC-Fal-036999	Ficedula albicollis	80.95	0.00e+00	1183.00
IUUC-Fox-038050	Fusarium oxysporum	30.38	6.00e-08	51.20
IUUC-Gmo-039532	Gadus morhua	81.69	0.00e+00	935.00
IUUC-Gga-040215	Gallus gallus	82.64	0.00e+00	1219.00
IUUC-Gac-041582	Gasterosteus aculeatus	81.34	0.00e+00	951.00
IUUC-Ggo-045074	Gorilla gorilla	90.81	0.00e+00	1335.00
IUUC-Hsa-046486	Homo sapiens	90.87	0.00e+00	1305.00
IUUC-Lch-050265	Latimeria chalumnae	81.43	0.00e+00	986.00
IUUC-Loc-052015	Lepisosteus oculatus	78.19	0.00e+00	1103.00
IUUC-Mcc-055418	Macaca mulatta	90.53	0.00e+00	1332.00
IUUC-Meu-056859	Macropus eugenii	75.41	2.00e-150	526.00
IUUC-Mga-059582	Meleagris gallopavo	82.26	0.00e+00	1150.00
IUUC-Mmr-061648	Microcebus murinus	91.36	0.00e+00	1338.00
IUUC-Mdo-062785	Monodelphis domestica	84.56	0.00e+00	972.00
IUUC-Mmu-063807	Mus musculus	85.91	0.00e+00	1250.00
IUUC-Mpu-066279	Mustela putorius furo	89.27	0.00e+00	1048.00
IUUC-Mlu-067981	Myotis lucifugus	87.74	0.00e+00	1293.00
IUUC-Nle-070033	Nomascus leucogenys	90.84	0.00e+00	1299.00
IUUC-Ont-071932	Oreochromis niloticus	74.45	0.00e+00	1085.00
IUUC-Ocu-073854	Oryctolagus cuniculus	92.48	0.00e+00	1094.00
IUUC-Ola-087436	Oryzias latipes	73.14	0.00e+00	1049.00
IUUC-Oar-089952	Ovis aries	88.86	0.00e+00	1298.00
IUUC-Ptr-091649	Pan troglodytes	83.57	0.00e+00	1171.00
IUUC-Pan-091798	Papio anubis	90.67	0.00e+00	1332.00
IUUC-Psi-093728	Pelodiscus sinensis	80.56	0.00e+00	1196.00
IUUC-Pfo-096954	Poecilia formosa	74.52	0.00e+00	1070.00
IUUC-Pab-098461	Pongo abelii	90.39	0.00e+00	1323.00
IUUC-Pva-102458	Pteropus vampyrus	90.81	0.00e+00	1186.00
IUUC-Rno-105865	Rattus norvegicus	86.61	0.00e+00	1256.00
IUUC-Sha-107322	Sarcophilus harrisii	82.10	0.00e+00	963.00
IUUC-Ssc-116001	Sus scrofa	92.01	0.00e+00	1348.00
IUUC-Tgu-116994	Taeniopygia guttata	82.06	0.00e+00	1202.00
IUUC-Tru-117780	Takifugu rubripes	81.37	0.00e+00	935.00
IUUC-Tni-120794	Tetraodon nigroviridis	72.03	0.00e+00	1009.00
IUUC-Tbe-128118	Tupaia belangeri	74.73	0.00e+00	950.00
IUUC-Ttr-129220	Tursiops truncatus	83.55	0.00e+00	1191.00
IUUC-Vpa-130811	Vicugna pacos	85.88	0.00e+00	1219.00
IUUC-Xtr-132358	Xenopus tropicalis	79.86	0.00e+00	1176.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence