iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000017271.1	ENSSHAT00000020522.1	ENSSHAP00000020361.1
ENSSHAG00000017271.1	ENSSHAT00000020523.1	ENSSHAP00000020362.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.30e-13	48.4	229	257

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H+ ++t++a+ +d  l+++Gs  +t++++D
   Q: 229  HEHPITSVAWaPDgELFAVGS-FHTLRLCD 257
           99*********9978888887.689*9999 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MRLKISLLRE PKHQELVSCV GWTTAEELYS CSDDHQIVKW NLLTTETSQI VKLPDDIYPI 60
DLHWFPKSIG VKKQTQAESF VLTSSDGKFH LISKLGRVEK SVEAHCGAVL AGRWNYEGTA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGACTGA AGATCTCACT TCTAAGAGAA CCAAAACATA TCCTTTGTTC CTTAATAAAA 60
CTTATTTGGA CATTATTGCT GAATTATTTT ATAATTTTAC TTTTTTTCCT TATAGTTGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0005929--C:cilium
GO:0030992--C:intraciliary transport particle B
GO:0060349--P:bone morphogenesis
GO:0002062--P:chondrocyte differentiation
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:1905515--P:non-motile cilium assembly
GO:0001649--P:osteoblast differentiation
GO:0045880--P:positive regulation of smoothened signaling pathway
GO:0007224--P:smoothened signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001564	Ailuropoda melanoleuca	95.50	0.00e+00	889.00
IUUC-Apl-003721	Anas platyrhynchos	86.68	0.00e+00	1394.00
IUUC-Aca-004488	Anolis carolinensis	86.63	0.00e+00	1397.00
IUUC-Ame-011402	Astyanax mexicanus	81.08	0.00e+00	822.00
IUUC-Bta-013037	Bos taurus	85.41	0.00e+00	1305.00
IUUC-Cel-018360	Caenorhabditis elegans	40.34	0.00e+00	661.00
IUUC-Cja-019076	Callithrix jacchus	91.77	0.00e+00	1196.00
IUUC-Cfa-020999	Canis familiaris	94.81	0.00e+00	1498.00
IUUC-Cpo-021333	Cavia porcellus	84.35	0.00e+00	1285.00
IUUC-Cre-022899	Chlamydomonas reinhardtii	46.68	0.00e+00	682.00
IUUC-Csa-023699	Chlorocebus sabaeus	94.27	0.00e+00	1486.00
IUUC-Cho-024904	Choloepus hoffmanni	85.68	0.00e+00	818.00
IUUC-Cin-025399	Ciona intestinalis	57.09	0.00e+00	951.00
IUUC-Csv-026186	Ciona savignyi	54.86	0.00e+00	918.00
IUUC-Dre-028276	Danio rerio	74.84	0.00e+00	1272.00
IUUC-Dno-029824	Dasypus novemcinctus	95.10	0.00e+00	1508.00
IUUC-Dor-031141	Dipodomys ordii	89.96	0.00e+00	1420.00
IUUC-Dme-031620	Drosophila melanogaster	35.35	4.00e-144	505.00
IUUC-Ete-033028	Echinops telfairi	69.97	6.00e-151	528.00
IUUC-Eca-033339	Equus caballus	93.82	0.00e+00	1477.00
IUUC-Eeu-034909	Erinaceus europaeus	92.90	0.00e+00	985.00
IUUC-Fca-035780	Felis catus	95.34	0.00e+00	1472.00
IUUC-Fal-037447	Ficedula albicollis	79.97	0.00e+00	1281.00
IUUC-Gmo-038657	Gadus morhua	61.07	0.00e+00	835.00
IUUC-Gga-040689	Gallus gallus	87.43	0.00e+00	1398.00
IUUC-Gac-041586	Gasterosteus aculeatus	73.67	0.00e+00	1023.00
IUUC-Hsa-047005	Homo sapiens	94.23	0.00e+00	1508.00
IUUC-Itr-048757	Ictidomys tridecemlineatus	96.27	0.00e+00	1111.00
IUUC-Lch-050459	Latimeria chalumnae	80.95	0.00e+00	1326.00
IUUC-Loc-052774	Lepisosteus oculatus	79.02	0.00e+00	1067.00
IUUC-Laf-053765	Loxodonta africana	93.78	0.00e+00	1454.00
IUUC-Mcc-055052	Macaca mulatta	94.27	0.00e+00	1486.00
IUUC-Meu-056368	Macropus eugenii	84.94	0.00e+00	1328.00
IUUC-Mga-059488	Meleagris gallopavo	87.32	0.00e+00	1399.00
IUUC-Mmr-061527	Microcebus murinus	94.90	0.00e+00	1486.00
IUUC-Mdo-062850	Monodelphis domestica	98.26	0.00e+00	1257.00
IUUC-Mmu-063117	Mus musculus	93.98	0.00e+00	1487.00
IUUC-Mpu-066550	Mustela putorius furo	94.36	0.00e+00	1364.00
IUUC-Mlu-067772	Myotis lucifugus	90.55	0.00e+00	1392.00
IUUC-Nle-069215	Nomascus leucogenys	93.32	0.00e+00	1493.00
IUUC-Opr-070725	Ochotona princeps	72.64	0.00e+00	1105.00
IUUC-Ont-072147	Oreochromis niloticus	73.93	0.00e+00	1259.00
IUUC-Oan-073176	Ornithorhynchus anatinus	88.00	7.00e-63	231.00
IUUC-Ocu-073896	Oryctolagus cuniculus	94.52	0.00e+00	1211.00
IUUC-Ola-086767	Oryzias latipes	68.82	0.00e+00	953.00
IUUC-Oga-088113	Otolemur garnettii	93.45	0.00e+00	1504.00
IUUC-Oar-089683	Ovis aries	91.03	0.00e+00	1426.00
IUUC-Ptr-091563	Pan troglodytes	94.36	0.00e+00	1509.00
IUUC-Pan-092042	Papio anubis	94.01	0.00e+00	1484.00
IUUC-Psi-093306	Pelodiscus sinensis	88.27	0.00e+00	1462.00
IUUC-Ppa-095694	Physcomitrella patens	44.67	0.00e+00	714.00
IUUC-Pfo-096800	Poecilia formosa	72.69	0.00e+00	1244.00
IUUC-Pab-098356	Pongo abelii	94.10	0.00e+00	1505.00
IUUC-Pva-102246	Pteropus vampyrus	90.00	0.00e+00	1397.00
IUUC-Rno-105195	Rattus norvegicus	94.00	0.00e+00	1496.00
IUUC-Smo-109240	Selaginella moellendorffii	43.23	5.00e-174	604.00
IUUC-Sar-113301	Sorex araneus	84.35	5.00e-147	514.00
IUUC-Ssc-116040	Sus scrofa	94.90	3.00e-145	507.00
IUUC-Tgu-117127	Taeniopygia guttata	81.87	0.00e+00	1330.00
IUUC-Tru-118663	Takifugu rubripes	70.83	0.00e+00	1202.00
IUUC-Tsy-119207	Tarsius syrichta	82.72	0.00e+00	1293.00
IUUC-Tni-120705	Tetraodon nigroviridis	69.57	0.00e+00	1189.00
IUUC-Tbe-127434	Tupaia belangeri	85.37	0.00e+00	939.00
IUUC-Ttr-128937	Tursiops truncatus	95.05	0.00e+00	1503.00
IUUC-Vpa-130518	Vicugna pacos	90.09	0.00e+00	1385.00
IUUC-Xtr-131879	Xenopus tropicalis	77.71	0.00e+00	1281.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence