iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-021168

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03017331

Gene Name

TRIM59

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000030902.1	ENSCAFT00000045752.1	ENSCAFP00000042145.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	3.70e-06	27.2	6	89
E3 activity/RING/RING	1.70e-09	38.3	10	60

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk...........tcPvtrqpl.....teedlvPnltlrrliqawcee 71
           +e+ CpI + +++dP vlp+ +t+ r+++e  l+ +g+           +cP +r+ +       e+l  n +lr++i+++ +e
   Q: 6    DELTCPICYSIFEDPRVLPCSHTFCRNCLENVLQASGNfyiwrplriplKCPNCRSIIeiaptGIESLPVNFALRAIIEKYQQE 89
           7899*****************************999999**********99999986533321456777799999999999776 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefr..........CPlCr 46
           C+iC++ f+d p+vlpC H+f+++Cl+++     ++s++f+          CP Cr
   Q: 10   CPICYSIFED-PRVLPCSHTFCRNCLENV----LQASGNFYiwrplriplkCPNCR 60
           **********.***************999....667777766667777777****8 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MHNFEDELTC PICYSIFEDP RVLPCSHTFC RNCLENVLQA SGNFYIWRPL RIPLKCPNCR 60
SIIEIAPTGI ESLPVNFALR AIIEKYQQED HPDIVTCPEH YRQPLNVYCL LDKKLVCGHC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCACAATT TTGAGGATGA ATTAACATGT CCCATTTGCT ACAGTATTTT TGAAGATCCT 60
CGTGTACTAC CATGCTCTCA TACATTTTGT AGAAATTGCT TGGAAAACGT TCTTCAGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0005813--C:centrosome
GO:0005929--C:cilium
GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:0030992--C:intraciliary transport particle B
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0060271--P:cilium assembly
GO:0045087--P:innate immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046597--P:negative regulation of viral entry into host cell

KEGG

cfa:488133

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002249	Ailuropoda melanoleuca	94.55	0.00e+00	778.00
IUUC-Apl-003996	Anas platyrhynchos	57.78	9.00e-124	436.00
IUUC-Aca-005141	Anolis carolinensis	58.06	2.00e-133	468.00
IUUC-Ame-011353	Astyanax mexicanus	52.41	1.00e-100	359.00
IUUC-Bta-013440	Bos taurus	92.82	0.00e+00	693.00
IUUC-Cpo-021702	Cavia porcellus	78.45	1.00e-180	625.00
IUUC-Csa-024141	Chlorocebus sabaeus	89.53	0.00e+00	679.00
IUUC-Dre-028408	Danio rerio	47.76	2.00e-89	322.00
IUUC-Dno-029180	Dasypus novemcinctus	90.52	0.00e+00	743.00
IUUC-Ete-033028	Echinops telfairi	87.77	3.00e-169	588.00
IUUC-Eca-034357	Equus caballus	92.00	0.00e+00	726.00
IUUC-Fca-036287	Felis catus	96.01	0.00e+00	786.00
IUUC-Gga-040739	Gallus gallus	57.88	2.00e-137	481.00
IUUC-Ggo-045307	Gorilla gorilla	88.06	0.00e+00	711.00
IUUC-Hsa-045690	Homo sapiens	88.78	0.00e+00	712.00
IUUC-Itr-048230	Ictidomys tridecemlineatus	92.77	0.00e+00	772.00
IUUC-Laf-054522	Loxodonta africana	88.28	0.00e+00	732.00
IUUC-Mcc-055145	Macaca mulatta	89.53	0.00e+00	718.00
IUUC-Meu-056214	Macropus eugenii	48.07	2.00e-61	229.00
IUUC-Mmr-061197	Microcebus murinus	94.76	0.00e+00	786.00
IUUC-Mdo-062631	Monodelphis domestica	60.35	6.00e-134	470.00
IUUC-Mmu-064217	Mus musculus	86.39	0.00e+00	695.00
IUUC-Mpu-065691	Mustela putorius furo	96.76	0.00e+00	796.00
IUUC-Mlu-067742	Myotis lucifugus	90.02	0.00e+00	716.00
IUUC-Nle-069722	Nomascus leucogenys	89.03	0.00e+00	741.00
IUUC-Oan-073382	Ornithorhynchus anatinus	59.35	7.00e-136	476.00
IUUC-Oar-089206	Ovis aries	90.77	0.00e+00	756.00
IUUC-Pan-092189	Papio anubis	89.78	0.00e+00	720.00
IUUC-Psi-093523	Pelodiscus sinensis	62.22	2.00e-143	501.00
IUUC-Pma-094162	Petromyzon marinus	36.63	1.00e-47	183.00
IUUC-Pfo-096032	Poecilia formosa	46.30	3.00e-88	318.00
IUUC-Pva-103089	Pteropus vampyrus	93.02	0.00e+00	742.00
IUUC-Pgr-103338	Puccinia graminis	38.10	1.00e-06	46.60
IUUC-Rno-105440	Rattus norvegicus	88.53	0.00e+00	712.00
IUUC-Ssc-115809	Sus scrofa	91.02	0.00e+00	724.00
IUUC-Tru-118402	Takifugu rubripes	44.35	9.00e-94	336.00
IUUC-Tni-119737	Tetraodon nigroviridis	45.02	3.00e-85	308.00
IUUC-Ttr-128921	Tursiops truncatus	91.02	0.00e+00	734.00
IUUC-Vpa-130397	Vicugna pacos	93.77	0.00e+00	776.00
IUUC-Xtr-132752	Xenopus tropicalis	44.99	5.00e-84	304.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence