iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Spo-108352

UUCD1 version

UUC-ScP-00182

Ensembl Protein ID

SPBC32H8.07.1:pep

UniProt Accession

Q10282; GBB_SCHPO

Genbank Protein ID

AAC37501.1; AAD09020.1; BAA21396.1; CAC37497.1

Protein Name

Guanine nucleotide-binding protein subunit beta

Genbank Nucleotide ID

L28061; AF092102; AB004535; CU329671

Gene Name

git5; gpb1; pi017; SPBC32H8.07

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPBC32H8.07	SPBC32H8.07.1	SPBC32H8.07.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	HINT	Mentha
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.50e-34	112.7	272	302
UBD/Beta-Prp	2.50e-50	169.4	101	302

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH++++++la+ sd t+l++Gs+D  +++W+
   Q: 272  GHENRISSLALtSDgTMLATGSWDECVRLWS 302
           8***********999***************8 PP

UBD/Beta-Prp

   S: 47   slsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsg.dklvsGshdrtirvwdletgqcleetlsghd 137
           +l gh ++v+++k+ +dg  l+tgs D+t   wd+++ k +++lkghe +++sl+f ps+ + +v+G+ d+ +++wdl+  +c   t+ g++
   Q: 101  ELVGHAGFVSCCKYVDDG-HLLTGSGDKTCMFWDIEQAKAISVLKGHEMDIVSLDFLPSNpNLFVTGGCDKLAKLWDLRAAYCCA-TFPGNT 190
           5889*************9.8**************************************777************************.****** PP
   S: 138  gvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvr 229
           + +n++++ p++  +v+G+ D++ r +d++    + + ++   ++++s+ f+++g  l+ +++d+t ++wd  +++++ +l+gh++ ++s++
   Q: 191  SDINSISFFPSNADFVTGAEDGIARCFDIRASAEIFQYSSPSSSPINSVLFSKSG-KLLFIAKDKTCEVWDSISSKTITSLTGHENRISSLA 281
           **************************************999************87.8999******************************** PP
   S: 230  fspnderlvsgssDgsiriWd 250
           ++++++ l++gs D+ +r+W 
   Q: 282  LTSDGTMLATGSWDECVRLWS 302
           ********************6 PP

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Required for adenylate cyclase activation.

Protein Sequence
(Fasta)

MDSGSRVNVN IQGTRVLKNK LGKIPDIDIS TDGKYLLSAS TNDVLLVWDL HTSNKVAFFE 60
APSVWIMTCA FSPSTKSIAA GGLNNFCVVY DTSVPDADPV ELVGHAGFVS CCKYVDDGHL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCCCAATA CTCTTCTTTT GACCTTAGCT CTTTACATAA ATTCCAGTAA AAAAGCGAAG 60
AAAGCCGTTT TTTTGTGTTT GTTGAAAAAC GATACGTTGG TCCTTTTGGT GTTTATGTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0749--Sporulation
KW-0807--Transducer
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005834--C:heterotrimeric G-protein complex
GO:0005634--C:nucleus
GO:0030159--F:receptor signaling complex scaffold activity
GO:0004871--F:signal transducer activity
GO:0007190--P:activation of adenylate cyclase activity
GO:0010619--P:adenylate cyclase-activating glucose-activated G-protein coupled receptor signaling pathway
GO:0031138--P:negative regulation of conjugation with cellular fusion
GO:0045014--P:negative regulation of transcription by glucose
GO:0043950--P:positive regulation of cAMP-mediated signaling
GO:0032092--P:positive regulation of protein binding
GO:0008277--P:regulation of G-protein coupled receptor protein signaling pathway
GO:0030435--P:sporulation resulting in formation of a cellular spore

KEGG

spo:SPBC32H8.07

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000161	Aegilops tauschii	38.29	6.00e-49	185.00
IUUC-Aml-001727	Ailuropoda melanoleuca	41.69	4.00e-70	256.00
IUUC-Atr-002610	Amborella trichopoda	38.85	5.00e-63	232.00
IUUC-Apl-004079	Anas platyrhynchos	42.67	2.00e-70	256.00
IUUC-Aca-004539	Anolis carolinensis	41.33	6.00e-69	252.00
IUUC-Aly-006025	Arabidopsis lyrata	40.45	2.00e-63	234.00
IUUC-Ath-006617	Arabidopsis thaliana	40.45	3.00e-63	233.00
IUUC-Ago-007831	Ashbya gossypii	29.63	3.00e-38	150.00
IUUC-Acl-008154	Aspergillus clavatus	44.26	3.00e-71	259.00
IUUC-Afl-008568	Aspergillus flavus	43.67	7.00e-73	265.00
IUUC-Afu-008789	Aspergillus fumigatus	44.26	1.00e-71	261.00
IUUC-Ani-009213	Aspergillus nidulans	43.33	2.00e-72	263.00
IUUC-Ang-009836	Aspergillus niger	43.67	5.00e-73	265.00
IUUC-Aor-010165	Aspergillus oryzae	43.67	7.00e-73	265.00
IUUC-Ate-010520	Aspergillus terreus	37.19	4.00e-55	206.00
IUUC-Ame-011092	Astyanax mexicanus	42.67	1.00e-71	261.00
IUUC-Bgr-012079	Blumeria graminis	44.11	2.00e-71	260.00
IUUC-Bta-013200	Bos taurus	41.69	4.00e-70	256.00
IUUC-Bci-013621	Botrytis cinerea	44.04	2.00e-73	266.00
IUUC-Bdi-014785	Brachypodium distachyon	39.24	7.00e-60	222.00
IUUC-Bol-015657	Brassica oleracea	39.49	1.00e-61	227.00
IUUC-Bra-017618	Brassica rapa	39.17	3.00e-61	226.00
IUUC-Cel-018704	Caenorhabditis elegans	42.67	3.00e-71	259.00
IUUC-Cja-019894	Callithrix jacchus	44.00	6.00e-70	255.00
IUUC-Cfa-020395	Canis familiaris	41.69	4.00e-70	256.00
IUUC-Cpo-021376	Cavia porcellus	41.69	5.00e-70	255.00
IUUC-Csa-023295	Chlorocebus sabaeus	41.69	4.00e-70	256.00
IUUC-Cho-024766	Choloepus hoffmanni	41.69	5.00e-70	255.00
IUUC-Cin-025309	Ciona intestinalis	41.81	2.00e-69	253.00
IUUC-Csv-026258	Ciona savignyi	42.14	6.00e-70	255.00
IUUC-Cgl-026673	Colletotrichum gloeosporioides	44.52	2.00e-73	267.00
IUUC-Cne-026811	Cryptococcus neoformans	41.89	1.00e-67	248.00
IUUC-Dre-027412	Danio rerio	42.33	4.00e-71	259.00
IUUC-Dno-029783	Dasypus novemcinctus	43.67	1.00e-69	254.00
IUUC-Dor-030964	Dipodomys ordii	39.13	3.00e-59	219.00
IUUC-Dse-031388	Dothistroma septosporum	43.77	5.00e-72	262.00
IUUC-Dme-031748	Drosophila melanogaster	42.00	2.00e-70	256.00
IUUC-Ete-032710	Echinops telfairi	41.00	6.00e-69	251.00
IUUC-Eca-033628	Equus caballus	41.69	3.00e-70	256.00
IUUC-Eeu-034631	Erinaceus europaeus	40.33	4.00e-61	226.00
IUUC-Fca-035392	Felis catus	43.00	6.00e-69	252.00
IUUC-Fal-036902	Ficedula albicollis	41.67	1.00e-69	254.00
IUUC-Fox-037946	Fusarium oxysporum	44.85	4.00e-74	269.00
IUUC-Fso-038136	Fusarium solani	44.85	4.00e-74	269.00
IUUC-Gmo-039709	Gadus morhua	42.33	4.00e-71	259.00
IUUC-Ggr-039969	Gaeumannomyces graminis	44.52	2.00e-72	263.00
IUUC-Gga-040655	Gallus gallus	42.67	5.00e-70	255.00
IUUC-Gac-041386	Gasterosteus aculeatus	42.67	1.00e-71	261.00
IUUC-Gma-043322	Glycine max	39.81	1.00e-61	228.00
IUUC-Ggo-044954	Gorilla gorilla	41.69	3.00e-70	256.00
IUUC-Hsa-046105	Homo sapiens	41.69	4.00e-70	256.00
IUUC-Hvu-047596	Hordeum vulgare	39.24	1.00e-59	221.00
IUUC-Itr-048623	Ictidomys tridecemlineatus	41.69	5.00e-70	255.00
IUUC-Kpa-049192	Komagataella pastoris	29.35	1.00e-39	154.00
IUUC-Lch-049422	Latimeria chalumnae	42.00	6.00e-68	248.00
IUUC-Lpe-051040	Leersia perrieri	38.61	6.00e-59	219.00
IUUC-Loc-052939	Lepisosteus oculatus	42.33	2.00e-71	260.00
IUUC-Lma-052985	Leptosphaeria maculans	43.00	6.00e-71	258.00
IUUC-Laf-053616	Loxodonta africana	43.67	2.00e-69	253.00
IUUC-Mcc-055787	Macaca mulatta	41.69	4.00e-70	256.00
IUUC-Meu-056109	Macropus eugenii	42.33	5.00e-68	249.00
IUUC-Mor-057188	Magnaporthe oryzae	44.52	2.00e-72	263.00
IUUC-Mpo-057544	Magnaporthe poae	44.52	3.00e-72	263.00
IUUC-Mtr-058752	Medicago truncatula	39.37	4.00e-61	226.00
IUUC-Mla-059086	Melampsora laricipopulina	41.00	6.00e-68	248.00
IUUC-Mga-059516	Meleagris gallopavo	42.67	4.00e-70	256.00
IUUC-Mvi-060482	Microbotryum violaceum	41.00	5.00e-68	249.00
IUUC-Mmr-060931	Microcebus murinus	41.69	4.00e-70	256.00
IUUC-Mdo-061879	Monodelphis domestica	42.67	1.00e-69	254.00
IUUC-Mmu-063132	Mus musculus	43.33	2.00e-69	254.00
IUUC-Mac-064871	Musa acuminata	37.84	9.00e-57	211.00
IUUC-Mpu-066358	Mustela putorius furo	41.69	4.00e-70	256.00
IUUC-Mlu-067628	Myotis lucifugus	44.00	3.00e-70	256.00
IUUC-Nfi-068332	Neosartorya fischeri	44.26	2.00e-71	260.00
IUUC-Ncr-068650	Neurospora crassa	45.49	1.00e-70	258.00
IUUC-Nle-069612	Nomascus leucogenys	41.69	4.00e-70	256.00
IUUC-Opr-070261	Ochotona princeps	43.33	4.00e-69	252.00
IUUC-Ont-071280	Oreochromis niloticus	42.33	4.00e-71	259.00
IUUC-Oan-072780	Ornithorhynchus anatinus	42.00	4.00e-68	249.00
IUUC-Ocu-073769	Oryctolagus cuniculus	42.33	2.00e-68	250.00
IUUC-Oba-075818	Oryza barthii	39.14	7.00e-57	212.00
IUUC-Obr-076229	Oryza brachyantha	38.92	5.00e-55	206.00
IUUC-Ogl-077730	Oryza glaberrima	38.92	3.00e-59	220.00
IUUC-Ogu-078583	Oryza glumaepatula	40.91	8.00e-51	191.00
IUUC-Oin-079661	Oryza indica	38.61	5.00e-56	209.00
IUUC-Olo-080225	Oryza longistaminata	40.91	8.00e-51	191.00
IUUC-Oni-082161	Oryza nivara	38.61	6.00e-59	219.00
IUUC-Opu-084072	Oryza punctata	38.92	4.00e-59	219.00
IUUC-Oru-084316	Oryza rufipogon	38.92	5.00e-56	209.00
IUUC-Osa-085380	Oryza sativa	38.92	5.00e-56	209.00
IUUC-Ola-087490	Oryzias latipes	41.67	2.00e-70	257.00
IUUC-Oga-087961	Otolemur garnettii	42.33	2.00e-68	250.00
IUUC-Oar-089360	Ovis aries	41.69	6.00e-70	255.00
IUUC-Ptr-091437	Pan troglodytes	41.69	4.00e-70	256.00
IUUC-Pan-092195	Papio anubis	41.69	7.00e-70	255.00
IUUC-Psi-092965	Pelodiscus sinensis	42.33	9.00e-70	254.00
IUUC-Pma-094748	Petromyzon marinus	43.27	1.00e-58	217.00
IUUC-Pno-095135	Phaeosphaeria nodorum	43.00	5.00e-71	259.00
IUUC-Ppa-095726	Physcomitrella patens	37.35	4.00e-50	189.00
IUUC-Pfo-097028	Poecilia formosa	42.33	5.00e-71	259.00
IUUC-Pab-098335	Pongo abelii	43.67	5.00e-70	255.00
IUUC-Pop-099370	Populus trichocarpa	38.85	3.00e-60	223.00
IUUC-Pca-100940	Procavia capensis	40.67	6.00e-68	248.00
IUUC-Ppe-102016	Prunus persica	39.81	1.00e-61	228.00
IUUC-Pva-102636	Pteropus vampyrus	42.33	2.00e-68	250.00
IUUC-Pgr-103321	Puccinia graminis	41.33	4.00e-68	249.00
IUUC-Ptt-103728	Puccinia triticina	41.33	4.00e-68	249.00
IUUC-Pte-104053	Pyrenophora teres	43.00	6.00e-71	258.00
IUUC-Pyt-104426	Pyrenophora triticirepentis	40.20	4.00e-63	233.00
IUUC-Rno-105834	Rattus norvegicus	43.33	4.00e-69	252.00
IUUC-Sce-106298	Saccharomyces cerevisiae	30.14	2.00e-42	164.00
IUUC-Sha-107128	Sarcophilus harrisii	42.67	1.00e-69	254.00
IUUC-Sja-107891	Schizosaccharomyces japonicus	40.79	1.00e-72	264.00
IUUC-Ssl-108539	Sclerotinia sclerotiorum	43.52	2.00e-72	264.00
IUUC-Smo-108835	Selaginella moellendorffii	36.08	1.00e-54	204.00
IUUC-Sit-110441	Setaria italica	37.66	7.00e-58	215.00
IUUC-Sly-111784	Solanum lycopersicum	40.45	1.00e-62	231.00
IUUC-Stu-112400	Solanum tuberosum	40.45	1.00e-62	231.00
IUUC-Sar-113642	Sorex araneus	43.38	1.00e-65	241.00
IUUC-Sbi-114038	Sorghum bicolor	37.66	2.00e-57	214.00
IUUC-Sre-115035	Sporisorium reilianum	41.95	4.00e-69	252.00
IUUC-Ssc-115886	Sus scrofa	43.33	2.00e-69	254.00
IUUC-Tgu-116461	Taeniopygia guttata	42.00	3.00e-70	256.00
IUUC-Tru-117793	Takifugu rubripes	42.00	4.00e-71	259.00
IUUC-Tsy-119354	Tarsius syrichta	41.00	1.00e-68	251.00
IUUC-Tni-120495	Tetraodon nigroviridis	41.33	1.00e-68	251.00
IUUC-Tca-121224	Theobroma cacao	39.17	2.00e-61	227.00
IUUC-Tre-122156	Trichoderma reesei	44.52	2.00e-73	266.00
IUUC-Tvi-122640	Trichoderma virens	44.52	2.00e-73	266.00
IUUC-Tae-124407	Triticum aestivum	38.92	1.00e-59	221.00
IUUC-Tur-126755	Triticum urartu	38.78	1.00e-57	216.00
IUUC-Tme-126886	Tuber melanosporum	44.37	7.00e-73	265.00
IUUC-Tbe-128132	Tupaia belangeri	42.02	2.00e-57	213.00
IUUC-Ttr-129243	Tursiops truncatus	41.69	4.00e-70	256.00
IUUC-Uma-129589	Ustilago maydis	41.95	4.00e-69	252.00
IUUC-Vda-129855	Verticillium dahliae	44.63	4.00e-73	266.00
IUUC-Vpa-130173	Vicugna pacos	34.22	7.00e-38	149.00
IUUC-Vvi-131162	Vitis vinifera	39.49	5.00e-61	226.00
IUUC-Xtr-132928	Xenopus tropicalis	44.00	2.00e-71	260.00
IUUC-Xma-133743	Xiphophorus maculatus	42.33	5.00e-71	259.00
IUUC-Yli-134396	Yarrowia lipolytica	32.37	3.00e-44	170.00
IUUC-Zma-135893	Zea mays	37.66	4.00e-57	213.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence