iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004821

UUCD1 version

UUC-AnC-00539

Ensembl Protein ID

ENSACAP00000004676.1

UniProt Accession

G1KD61; G1KD61_ANOCA

Protein Name

Uncharacterized protein

Gene Name

KLHL24

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000004768.1	ENSACAT00000004783.1	ENSACAP00000004676.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.10e-21	76.9	66	131
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.40e-08	32.1	167	196

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dvi++v+g+ef++h++vL+a+Ss+F+a+f ++ +es+ +  vei+++ +e++  +l+++Ytgk+++
   Q: 66   TDVIICVEGREFPCHRAVLSACSSYFRAMFCNDHRESR-EMLVEINGIFAEAMDCFLQYVYTGKVKI 131
           7************************************9.999**********************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 3    NclgilrfAdlydcpdLkdaaldfilkhFk 32
           Nclgi rfAd++++  L  ++++f+l++F+
   Q: 167  NCLGIQRFADTHSLKTLFTKCRNFALQNFE 196
           *****************************5 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MVLILGRRLN RGDSRAQESP VTKRKVFEMD PKSLSGHEFF DFSSGSSHAE SILQIFNEFR 60
DSRLFTDVII CVEGREFPCH RAVLSACSSY FRAMFCNDHR ESREMLVEIN GIFAEAMDCF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTACTAA TATTGGGTCG CAGATTGAAC AGAGGGGACA GCCGGGCCCA GGAATCCCCA 60
GTGACAAAAC GTAAAGTTTT TGAAATGGAC CCAAAATCCT TATCGGGTCA TGAGTTCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030596--KLHL24
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination
GO:2000312--P:regulation of kainate selective glutamate receptor activity

KEGG

acs:100552977

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001447	Ailuropoda melanoleuca	94.52	0.00e+00	1159.00
IUUC-Ame-010778	Astyanax mexicanus	84.97	0.00e+00	1090.00
IUUC-Bta-012622	Bos taurus	94.35	0.00e+00	1155.00
IUUC-Bdi-014963	Brachypodium distachyon	28.24	1.00e-15	78.60
IUUC-Cja-018938	Callithrix jacchus	94.83	0.00e+00	1163.00
IUUC-Cfa-020831	Canis familiaris	94.83	0.00e+00	1164.00
IUUC-Cpo-021569	Cavia porcellus	94.00	0.00e+00	1152.00
IUUC-Csa-024070	Chlorocebus sabaeus	95.00	0.00e+00	1165.00
IUUC-Cin-025465	Ciona intestinalis	52.64	0.00e+00	645.00
IUUC-Csv-025878	Ciona savignyi	53.25	0.00e+00	634.00
IUUC-Dre-028103	Danio rerio	85.28	0.00e+00	1084.00
IUUC-Dno-029374	Dasypus novemcinctus	93.85	0.00e+00	1149.00
IUUC-Dor-030922	Dipodomys ordii	83.62	1.00e-139	489.00
IUUC-Ete-032909	Echinops telfairi	93.50	0.00e+00	1140.00
IUUC-Eca-034390	Equus caballus	94.50	0.00e+00	1159.00
IUUC-Fca-036449	Felis catus	94.67	0.00e+00	1160.00
IUUC-Fal-036612	Ficedula albicollis	95.67	0.00e+00	1171.00
IUUC-Gmo-038760	Gadus morhua	81.14	0.00e+00	1034.00
IUUC-Gga-040779	Gallus gallus	94.85	0.00e+00	730.00
IUUC-Gac-042145	Gasterosteus aculeatus	81.30	0.00e+00	1045.00
IUUC-Ggo-045506	Gorilla gorilla	94.52	0.00e+00	1158.00
IUUC-Hsa-046510	Homo sapiens	95.00	0.00e+00	1165.00
IUUC-Itr-048255	Ictidomys tridecemlineatus	94.35	0.00e+00	1157.00
IUUC-Lch-049594	Latimeria chalumnae	86.58	0.00e+00	1086.00
IUUC-Loc-052147	Lepisosteus oculatus	85.79	0.00e+00	1075.00
IUUC-Laf-054224	Loxodonta africana	94.35	0.00e+00	1156.00
IUUC-Meu-056366	Macropus eugenii	93.12	2.00e-152	532.00
IUUC-Mga-059535	Meleagris gallopavo	95.00	0.00e+00	1150.00
IUUC-Mdo-063082	Monodelphis domestica	94.00	0.00e+00	1152.00
IUUC-Mmu-063152	Mus musculus	94.33	0.00e+00	1160.00
IUUC-Mpu-065928	Mustela putorius furo	94.83	0.00e+00	1164.00
IUUC-Mlu-068041	Myotis lucifugus	94.02	0.00e+00	1154.00
IUUC-Nle-069293	Nomascus leucogenys	95.00	0.00e+00	1165.00
IUUC-Opr-070368	Ochotona princeps	95.00	0.00e+00	1164.00
IUUC-Ont-071571	Oreochromis niloticus	80.80	0.00e+00	1014.00
IUUC-Oan-072849	Ornithorhynchus anatinus	94.67	0.00e+00	1165.00
IUUC-Ocu-073987	Oryctolagus cuniculus	94.35	0.00e+00	1157.00
IUUC-Ola-087513	Oryzias latipes	80.80	0.00e+00	1045.00
IUUC-Oga-088595	Otolemur garnettii	94.52	0.00e+00	1158.00
IUUC-Oar-089935	Ovis aries	94.35	0.00e+00	1155.00
IUUC-Ptr-091664	Pan troglodytes	94.67	0.00e+00	1155.00
IUUC-Pan-091881	Papio anubis	94.68	0.00e+00	1160.00
IUUC-Psi-092983	Pelodiscus sinensis	95.67	0.00e+00	1174.00
IUUC-Pfo-096218	Poecilia formosa	77.22	0.00e+00	987.00
IUUC-Pab-098487	Pongo abelii	95.00	0.00e+00	1165.00
IUUC-Pca-100916	Procavia capensis	94.17	0.00e+00	1157.00
IUUC-Pva-103010	Pteropus vampyrus	94.50	0.00e+00	1158.00
IUUC-Rno-105025	Rattus norvegicus	94.00	0.00e+00	1150.00
IUUC-Sha-106793	Sarcophilus harrisii	94.83	0.00e+00	1161.00
IUUC-Sar-113290	Sorex araneus	84.00	0.00e+00	1030.00
IUUC-Ssc-115631	Sus scrofa	94.35	0.00e+00	1155.00
IUUC-Tgu-116856	Taeniopygia guttata	95.83	0.00e+00	1173.00
IUUC-Tru-118210	Takifugu rubripes	81.50	0.00e+00	1017.00
IUUC-Tsy-118964	Tarsius syrichta	92.16	4.00e-170	591.00
IUUC-Tni-120462	Tetraodon nigroviridis	81.21	0.00e+00	1013.00
IUUC-Tbe-128114	Tupaia belangeri	92.16	1.00e-166	579.00
IUUC-Ttr-128565	Tursiops truncatus	94.33	0.00e+00	1157.00
IUUC-Vpa-130093	Vicugna pacos	84.67	0.00e+00	1016.00
IUUC-Xtr-132233	Xenopus tropicalis	89.67	0.00e+00	1116.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence