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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Dme-032107
UUCD1 version UUC-DrM-00033
Ensembl Protein ID FBpp0307415
UniProt Accession Q9VGE5; Q9VGE5_DROME
Genbank Protein ID AAF54737.1; AAK93374.1; AGB95876.1
Protein Name KLHL18, isoform A; KLHL18, isoform C; LD42169p
Genbank Nucleotide ID AE014297; AY051950; AE014297
Gene Name KLHL18; CG3571; Dmel_CG3571
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0037978 FBtr0335434 FBpp0307415
FBgn0037978 FBtr0082557 FBpp0082030
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IIDiRefIndexPINA
Protein Expression/Proteomics
Status Reviewed
Details
Family Domain References (PMIDs)
E3 adaptor/Cullin RING/BCR/BTB_3-box BTB_3-box 19624754; 23213400
Classification
Family E-value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB 9.80e-20 70.7 39 106
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box 4.90e-13 48.0 140 170
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB
   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd..vqpevfrallkFlYtgklde 67
           +Dv+l+v+++ f+ah++vLaa  ++Fya+f++++ es+  +++++k+  ++p++++ l++++Y+g++++
   Q: 39   CDVTLKVEDQTFSAHRVVLAATIPYFYAMFTNNMAESR-IKEITMKEsaIEPSALESLINYVYSGQVRI 106
           9*************************************.*******779*****************986 PP
   

   E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box
   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++N+lgi++fAd + c++L daa+++i ++F
   Q: 140  PHNVLGIRTFADSMICRQLIDAADKYIDQNF 170
           79****************************9 PP
   
Organism Drosophila melanogaster
Protein Sequence
(Fasta)
MDLSDNSQVE DQYFVYKHDK LFGESFPLFK EIRRMGKLCD VTLKVEDQTF SAHRVVLAAT 60
IPYFYAMFTN NMAESRIKEI TMKESAIEPS ALESLINYVY SGQVRIDNQN VQNLMVGASF 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dme-032107|E3,BTB_3-box|Drosophila melanogaster
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTGCAGTACA AGCAACATTT GGCATCTCTA CTGTTTATCA TTTTCTTGAT CCGTTAAAGT 60
GATGGATTTG AGTGATAATA GCCAAGTGGA GGATCAATAC TTTGTTTACA AGCATGATAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dme-032107|E3,BTB_3-box|Drosophila melanogaster
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat
Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ
PROSITE

PS50097--BTB
Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1
SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch
Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0003779--F:actin binding
GO:0042803--F:protein homodimerization activity
GO:0046529--P:imaginal disc fusion, thorax closure
GO:0016567--P:protein ubiquitination
KEGG dme:Dmel_CG3571
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000220 Aegilops tauschii 35.27 4.00e-37 149.00
IUUC-Aml-001536 Ailuropoda melanoleuca 55.32 0.00e+00 660.00
IUUC-Apl-003270 Anas platyrhynchos 53.58 7.00e-172 596.00
IUUC-Aca-005395 Anolis carolinensis 56.14 0.00e+00 665.00
IUUC-Acl-008230 Aspergillus clavatus 24.49 4.00e-06 44.30
IUUC-Bta-013481 Bos taurus 54.64 0.00e+00 650.00
IUUC-Bol-015530 Brassica oleracea 25.00 3.00e-15 75.90
IUUC-Bra-017337 Brassica rapa 25.52 1.00e-15 77.40
IUUC-Cel-018622 Caenorhabditis elegans 44.42 4.00e-144 504.00
IUUC-Cja-019847 Callithrix jacchus 54.77 0.00e+00 654.00
IUUC-Cfa-020341 Canis familiaris 55.32 0.00e+00 660.00
IUUC-Cpo-021613 Cavia porcellus 54.36 0.00e+00 630.00
IUUC-Cre-022734 Chlamydomonas reinhardtii 41.86 3.00e-05 43.50
IUUC-Csa-023611 Chlorocebus sabaeus 54.77 0.00e+00 654.00
IUUC-Cin-025289 Ciona intestinalis 49.64 4.00e-161 560.00
IUUC-Dre-028248 Danio rerio 54.05 0.00e+00 649.00
IUUC-Dno-029609 Dasypus novemcinctus 54.77 0.00e+00 661.00
IUUC-Eca-033507 Equus caballus 54.80 0.00e+00 633.00
IUUC-Eeu-034750 Erinaceus europaeus 51.51 3.00e-164 570.00
IUUC-Fca-035731 Felis catus 55.14 0.00e+00 663.00
IUUC-Fal-036959 Ficedula albicollis 55.90 0.00e+00 648.00
IUUC-Gga-040166 Gallus gallus 55.64 0.00e+00 662.00
IUUC-Ggo-044853 Gorilla gorilla 54.77 0.00e+00 656.00
IUUC-Hsa-046437 Homo sapiens 54.77 0.00e+00 652.00
IUUC-Hvu-047224 Hordeum vulgare 36.28 7.00e-40 158.00
IUUC-Itr-048529 Ictidomys tridecemlineatus 54.29 2.00e-175 607.00
IUUC-Lch-050195 Latimeria chalumnae 49.02 2.00e-160 558.00
IUUC-Lpe-051276 Leersia perrieri 36.82 2.00e-39 156.00
IUUC-Loc-051787 Lepisosteus oculatus 55.09 7.00e-179 619.00
IUUC-Laf-053489 Loxodonta africana 54.95 0.00e+00 658.00
IUUC-Mcc-055250 Macaca mulatta 54.29 0.00e+00 648.00
IUUC-Meu-056871 Macropus eugenii 51.35 2.00e-175 608.00
IUUC-Mor-057055 Magnaporthe oryzae 31.19 1.00e-08 52.80
IUUC-Mga-059425 Meleagris gallopavo 55.78 0.00e+00 656.00
IUUC-Mvi-060512 Microbotryum violaceum 24.59 2.00e-06 47.40
IUUC-Mmr-061394 Microcebus murinus 54.46 0.00e+00 654.00
IUUC-Mdo-062285 Monodelphis domestica 54.95 0.00e+00 661.00
IUUC-Mmu-063975 Mus musculus 54.46 0.00e+00 652.00
IUUC-Mac-064682 Musa acuminata 34.65 3.00e-40 159.00
IUUC-Mpu-066369 Mustela putorius furo 55.32 0.00e+00 661.00
IUUC-Mlu-067832 Myotis lucifugus 54.48 0.00e+00 627.00
IUUC-Nle-069338 Nomascus leucogenys 50.45 4.00e-168 583.00
IUUC-Opr-071035 Ochotona princeps 53.64 8.00e-125 439.00
IUUC-Ont-071440 Oreochromis niloticus 53.70 0.00e+00 632.00
IUUC-Opu-083716 Oryza punctata 34.45 1.00e-32 134.00
IUUC-Ola-087275 Oryzias latipes 54.58 0.00e+00 634.00
IUUC-Oga-087921 Otolemur garnettii 54.95 0.00e+00 659.00
IUUC-Oar-089968 Ovis aries 51.42 9.00e-167 579.00
IUUC-Ptr-091272 Pan troglodytes 54.77 0.00e+00 656.00
IUUC-Pan-092629 Papio anubis 54.77 0.00e+00 652.00
IUUC-Psi-093456 Pelodiscus sinensis 54.10 2.00e-171 594.00
IUUC-Pma-094509 Petromyzon marinus 54.17 5.00e-168 583.00
IUUC-Pfo-096450 Poecilia formosa 53.51 0.00e+00 632.00
IUUC-Pab-097917 Pongo abelii 53.15 0.00e+00 654.00
IUUC-Pop-099153 Populus trichocarpa 33.46 1.00e-35 143.00
IUUC-Pva-103189 Pteropus vampyrus 54.95 0.00e+00 659.00
IUUC-Sha-107283 Sarcophilus harrisii 55.08 0.00e+00 647.00
IUUC-Smo-109336 Selaginella moellendorffii 21.57 4.00e-09 55.50
IUUC-Stu-112032 Solanum tuberosum 35.66 2.00e-40 159.00
IUUC-Sar-112989 Sorex araneus 56.23 0.00e+00 638.00
IUUC-Sre-115118 Sporisorium reilianum 21.43 7.00e-04 39.70
IUUC-Tgu-117146 Taeniopygia guttata 50.37 3.00e-159 554.00
IUUC-Tru-118132 Takifugu rubripes 53.16 6.00e-176 609.00
IUUC-Tni-120892 Tetraodon nigroviridis 52.20 9.00e-175 605.00
IUUC-Tae-124761 Triticum aestivum 37.33 6.00e-40 158.00
IUUC-Tur-126089 Triticum urartu 36.24 6.00e-39 155.00
IUUC-Tbe-127347 Tupaia belangeri 54.60 0.00e+00 636.00
IUUC-Vpa-130796 Vicugna pacos 47.57 2.00e-151 528.00
IUUC-Xtr-132077 Xenopus tropicalis 51.17 1.00e-164 572.00
Created Date 25-Jun-2017

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