iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098718

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01078747

Gene Name

RNF125

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000009093.2	ENSPPYT00000010613.2	ENSPPYP00000010209.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.00e-09	37.4	37	76
E3 activity/RING/U-box	5.50e-11	42.5	33	98

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           Ca+Cle + + p+ ++CgHvf+++C+   +      ++++++CP+Cr
   Q: 37   CAVCLEVLHQ-PVRTRCGHVFCRSCIaTSL------KNNKWTCPYCR 76
           ********99.777***********95555......**********8 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawc 69
             f C++ le+ ++Pv + +G+++ rs+I+  l++++ tcP +r+ l +e +    + +r+ +++ 
   Q: 33   TSFDCAVCLEVLHQPVRTRCGHVFCRSCIATSLKNNKWTCPYCRAYLPSEGVPATDVAKRMKSEYK 98
           579******************************99999**********999999999999999986 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MGSVLSSDSG KSAPASATPR ALERRGDPEL PVTSFDCAVC LEVLHQPVRT RCGHVFCRSC 60
IATSLKNNKW TCPYCRAYLP SEGVPATDVA KRMKSEYKNC AECDTLVCLS EMRAHIRTCQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAAGCAGCT GTGTGTGATA GCTTGGAAGG TTTACTGCTG CAAGTCCTCT TCTCTGCAGT 60
TGAGGTTTCA GGTTTCAATC CTCCCAATAC CACAAGACAG AGCACCGGGC GGCTGCCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR034734--ZF_C2HC_RNF
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51803--ZF_C2HC_RNF
PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0000139--C:Golgi membrane
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0039536--P:negative regulation of RIG-I signaling pathway
GO:0032480--P:negative regulation of type I interferon production
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

pon:100460705

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001992	Ailuropoda melanoleuca	79.31	3.00e-103	367.00
IUUC-Aca-004839	Anolis carolinensis	52.25	2.00e-48	184.00
IUUC-Bta-012827	Bos taurus	77.92	3.00e-101	360.00
IUUC-Cja-018794	Callithrix jacchus	79.74	7.00e-103	366.00
IUUC-Cfa-021234	Canis familiaris	78.45	4.00e-93	333.00
IUUC-Cpo-022412	Cavia porcellus	69.40	4.00e-84	303.00
IUUC-Csa-023406	Chlorocebus sabaeus	82.76	2.00e-106	377.00
IUUC-Cho-024427	Choloepus hoffmanni	58.19	3.00e-49	187.00
IUUC-Dno-030085	Dasypus novemcinctus	78.88	4.00e-102	363.00
IUUC-Dor-030911	Dipodomys ordii	56.71	3.00e-58	218.00
IUUC-Ete-032469	Echinops telfairi	72.84	3.00e-94	337.00
IUUC-Eca-034352	Equus caballus	80.60	2.00e-103	367.00
IUUC-Eeu-034889	Erinaceus europaeus	78.88	3.00e-103	367.00
IUUC-Fca-036116	Felis catus	79.74	4.00e-96	343.00
IUUC-Hsa-046518	Homo sapiens	82.33	3.00e-105	374.00
IUUC-Itr-048344	Ictidomys tridecemlineatus	76.84	4.00e-73	266.00
IUUC-Laf-053363	Loxodonta africana	78.63	7.00e-102	362.00
IUUC-Meu-056101	Macropus eugenii	66.82	5.00e-77	280.00
IUUC-Mdo-062046	Monodelphis domestica	65.67	1.00e-80	292.00
IUUC-Mmu-063184	Mus musculus	60.71	1.00e-38	151.00
IUUC-Mpu-065708	Mustela putorius furo	77.59	3.00e-100	357.00
IUUC-Mlu-067561	Myotis lucifugus	72.88	1.00e-69	255.00
IUUC-Nle-069665	Nomascus leucogenys	79.91	6.00e-94	336.00
IUUC-Opr-070301	Ochotona princeps	66.38	1.00e-81	295.00
IUUC-Ocu-074562	Oryctolagus cuniculus	68.25	2.00e-41	160.00
IUUC-Oga-088958	Otolemur garnettii	81.03	7.00e-105	372.00
IUUC-Oar-089541	Ovis aries	74.43	4.00e-71	259.00
IUUC-Ptr-090989	Pan troglodytes	82.76	3.00e-106	377.00
IUUC-Pan-092372	Papio anubis	81.90	1.00e-105	375.00
IUUC-Pca-100453	Procavia capensis	76.72	8.00e-99	352.00
IUUC-Pva-102931	Pteropus vampyrus	79.31	4.00e-94	337.00
IUUC-Rno-105771	Rattus norvegicus	70.75	3.00e-80	291.00
IUUC-Sha-107557	Sarcophilus harrisii	65.67	3.00e-86	310.00
IUUC-Sar-113435	Sorex araneus	66.67	1.00e-40	157.00
IUUC-Ssc-116388	Sus scrofa	79.31	2.00e-103	367.00
IUUC-Tsy-119439	Tarsius syrichta	74.01	6.00e-71	259.00
IUUC-Tbe-127417	Tupaia belangeri	78.10	7.00e-55	206.00
IUUC-Ttr-129212	Tursiops truncatus	79.31	3.00e-103	367.00
IUUC-Vpa-130153	Vicugna pacos	76.72	2.00e-99	355.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence