iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tni-120833

Ensembl Protein ID

ENSTNIP00000004641.1

UniProt Accession

H3C8R9; H3C8R9_TETNG

Protein Name

Phosphoinositide phospholipase C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000006235.1	ENSTNIT00000009158.1	ENSTNIP00000008987.1
ENSTNIG00000006235.1	ENSTNIT00000009159.1	ENSTNIP00000008988.1
ENSTNIG00000006235.1	ENSTNIT00000004784.1	ENSTNIP00000004641.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.50e-10	40.4	758	812

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGl.fPenFvekl 62
           +v++lydy aq +deL + k   +l +  ++q++gW++g  +  gk+ l fP+n+ve+l
   Q: 758  TVKALYDYRAQREDELCFSKQALILNV--DKQEGGWWRG--DYGGKKQLwFPANYVEEL 812
           79******************9988888..9*********..676666655*******98 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

SLETGTVMTL FYQKKSQRPE RRTFQVRPDM RLLVWSRNPD KPEGELDIQD IRELRLGKGS 60
RDFERYPEEA RKLDAAHCFI VLYGQEFRLR TLSLAAFSEE EVNMWMTGLT WLMTDTQRAP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCCACT CCTACGTCAC CTCCTTCACC TCCCTGGAGG AGGTGTGGCC ACAGGTGTGT 60
GTAGCTCTTC CTCCTGGGTT CTGACGACCT CGGCGAGCGT CTGGATTCTC TGCTCCGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0442--Lipid degradation
KW-0443--Lipid metabolism
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0807--Transducer

Interpro

IPR000008--C2_dom
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001192--PI-PLC_fam
IPR016279--PLC-gamma
IPR017946--PLC-like_Pdiesterase_TIM-brl
IPR000909--PLipase_C_PInositol-sp_X_dom
IPR001711--PLipase_C_Pinositol-sp_Y
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50003--PH_DOMAIN
PS50007--PIPLC_X_DOMAIN
PS50008--PIPLC_Y_DOMAIN
PS50001--SH2
PS50002--SH3

Pfam

PF00168--C2
PF00388--PI-PLC-X
PF00387--PI-PLC-Y
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00390--PHPHLIPASEC
PR00401--SH2DOMAIN

SMART

SM00239--C2
SM00233--PH
SM00148--PLCXc
SM00149--PLCYc
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005509--F:calcium ion binding
GO:0004435--F:phosphatidylinositol phospholipase C activity
GO:0004871--F:signal transducer activity
GO:0035556--P:intracellular signal transduction
GO:0009395--P:phospholipid catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001452	Ailuropoda melanoleuca	67.22	0.00e+00	1706.00
IUUC-Apl-003541	Anas platyrhynchos	77.35	0.00e+00	1999.00
IUUC-Aca-005291	Anolis carolinensis	66.61	0.00e+00	1691.00
IUUC-Ame-011004	Astyanax mexicanus	59.58	0.00e+00	1491.00
IUUC-Bta-012660	Bos taurus	67.80	0.00e+00	1641.00
IUUC-Cja-019206	Callithrix jacchus	66.96	0.00e+00	1688.00
IUUC-Cfa-020257	Canis familiaris	67.52	0.00e+00	1648.00
IUUC-Cpo-022391	Cavia porcellus	64.46	0.00e+00	1583.00
IUUC-Cin-025520	Ciona intestinalis	48.19	0.00e+00	1101.00
IUUC-Dre-027944	Danio rerio	63.26	0.00e+00	1578.00
IUUC-Dno-029440	Dasypus novemcinctus	67.99	0.00e+00	1597.00
IUUC-Dor-031001	Dipodomys ordii	66.80	0.00e+00	1695.00
IUUC-Eca-033809	Equus caballus	67.52	0.00e+00	1650.00
IUUC-Eeu-035329	Erinaceus europaeus	51.33	0.00e+00	1164.00
IUUC-Fca-036510	Felis catus	67.36	0.00e+00	1650.00
IUUC-Fal-037454	Ficedula albicollis	77.78	0.00e+00	2042.00
IUUC-Gmo-038630	Gadus morhua	59.55	0.00e+00	1245.00
IUUC-Gga-040211	Gallus gallus	78.12	0.00e+00	2022.00
IUUC-Ggo-045063	Gorilla gorilla	67.41	0.00e+00	1708.00
IUUC-Hsa-046428	Homo sapiens	67.41	0.00e+00	1707.00
IUUC-Itr-048245	Ictidomys tridecemlineatus	67.23	0.00e+00	1696.00
IUUC-Lch-049812	Latimeria chalumnae	74.74	0.00e+00	1741.00
IUUC-Loc-052285	Lepisosteus oculatus	65.74	0.00e+00	1664.00
IUUC-Laf-053365	Loxodonta africana	67.41	0.00e+00	1646.00
IUUC-Mcc-054871	Macaca mulatta	67.33	0.00e+00	1700.00
IUUC-Meu-056724	Macropus eugenii	62.67	0.00e+00	1498.00
IUUC-Mga-059588	Meleagris gallopavo	78.35	0.00e+00	2030.00
IUUC-Mmr-061110	Microcebus murinus	67.17	0.00e+00	1699.00
IUUC-Mdo-062448	Monodelphis domestica	67.41	0.00e+00	1703.00
IUUC-Mmu-063565	Mus musculus	67.65	0.00e+00	1714.00
IUUC-Mpu-066683	Mustela putorius furo	67.49	0.00e+00	1708.00
IUUC-Mlu-067779	Myotis lucifugus	67.52	0.00e+00	1643.00
IUUC-Nle-069219	Nomascus leucogenys	69.22	0.00e+00	1490.00
IUUC-Opr-070766	Ochotona princeps	66.21	0.00e+00	1017.00
IUUC-Ocu-074361	Oryctolagus cuniculus	66.64	0.00e+00	1674.00
IUUC-Oga-088172	Otolemur garnettii	67.57	0.00e+00	1711.00
IUUC-Oar-090306	Ovis aries	65.56	0.00e+00	1587.00
IUUC-Ptr-090682	Pan troglodytes	67.33	0.00e+00	1707.00
IUUC-Pan-092835	Papio anubis	69.16	0.00e+00	1271.00
IUUC-Psi-093344	Pelodiscus sinensis	66.69	0.00e+00	1674.00
IUUC-Pfo-096984	Poecilia formosa	66.86	0.00e+00	1613.00
IUUC-Pab-097871	Pongo abelii	67.31	0.00e+00	1694.00
IUUC-Pca-100772	Procavia capensis	61.99	0.00e+00	1524.00
IUUC-Pva-102790	Pteropus vampyrus	68.69	0.00e+00	1696.00
IUUC-Rno-105974	Rattus norvegicus	67.49	0.00e+00	1714.00
IUUC-Sar-112995	Sorex araneus	66.64	0.00e+00	1670.00
IUUC-Ssc-115360	Sus scrofa	67.41	0.00e+00	1702.00
IUUC-Tgu-116585	Taeniopygia guttata	65.60	0.00e+00	1603.00
IUUC-Tsy-119259	Tarsius syrichta	70.52	1.00e-179	624.00
IUUC-Tbe-127504	Tupaia belangeri	59.84	0.00e+00	952.00
IUUC-Ttr-128392	Tursiops truncatus	49.30	0.00e+00	1146.00
IUUC-Xtr-132708	Xenopus tropicalis	76.84	0.00e+00	1908.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence