iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033422

UUCD1 version

UUC-EqC-00472

Ensembl Protein ID

ENSECAP00000014426.1

UniProt Accession

F6XMN0; F6XMN0_HORSE

Protein Name

Uncharacterized protein

Gene Name

CISH

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000016867.1	ENSECAT00000017743.1	ENSECAP00000014426.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	4.50e-15	55.4	209	256

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 1    lsklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           l++++++rs+ rSLqhLCRl+I+r++ +     +d+LPLP+++ dYL+++++q
   Q: 209  LVQPFVRRSSARSLQHLCRLVINRLVAD-----VDCLPLPRRMADYLRQYPFQ 256
           57999***********************.....8****************986 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MVLCVQGPCP LLAVEQIGQR PLWAQSLELP EPAMQPLPAG TFLEEVVEET PAQPESEPKV 60
LDPEEDLLCI AKTFSYLRES GWYWGSITAS EARQHLQKMP EGTFLVRDST HPSYLFTLSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTCCCTGCC CGCCGCCTGT GCGCCCCGGG AGCCTGCCCT ACGAGTGCGA TCCGCGCCCG 60
CTGGCTCCCT CCAGCCGCCG CCGTCCGGCC GAGCCCCAGC TCCGGAGCTG CCGCTGCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028425--CIS
IPR000980--SH2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005886--C:plasma membrane
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity
GO:0007205--P:protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0016567--P:protein ubiquitination

KEGG

ecb:100061510

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001189	Ailuropoda melanoleuca	95.24	1.00e-127	448.00
IUUC-Apl-003484	Anas platyrhynchos	44.38	2.00e-38	150.00
IUUC-Aca-004372	Anolis carolinensis	62.69	9.00e-86	309.00
IUUC-Ame-010787	Astyanax mexicanus	46.12	6.00e-52	196.00
IUUC-Bta-012826	Bos taurus	92.22	2.00e-131	461.00
IUUC-Cja-020004	Callithrix jacchus	90.84	1.00e-113	402.00
IUUC-Cfa-020150	Canis familiaris	93.20	7.00e-117	412.00
IUUC-Cpo-022414	Cavia porcellus	45.51	8.00e-40	156.00
IUUC-Csa-023173	Chlorocebus sabaeus	90.44	7.00e-114	402.00
IUUC-Cho-024471	Choloepus hoffmanni	41.53	1.00e-33	135.00
IUUC-Dre-028606	Danio rerio	44.63	5.00e-34	137.00
IUUC-Dno-028956	Dasypus novemcinctus	90.23	2.00e-127	447.00
IUUC-Dor-030148	Dipodomys ordii	75.10	4.00e-101	360.00
IUUC-Ete-032313	Echinops telfairi	85.16	1.00e-105	375.00
IUUC-Eeu-034806	Erinaceus europaeus	94.00	4.00e-115	407.00
IUUC-Fca-036374	Felis catus	96.89	3.00e-130	457.00
IUUC-Fal-036801	Ficedula albicollis	65.77	3.00e-88	317.00
IUUC-Gmo-038483	Gadus morhua	38.37	6.00e-36	144.00
IUUC-Gga-040891	Gallus gallus	66.02	2.00e-83	301.00
IUUC-Gac-042147	Gasterosteus aculeatus	39.85	2.00e-36	145.00
IUUC-Ggo-045511	Gorilla gorilla	90.44	5.00e-115	406.00
IUUC-Hsa-046678	Homo sapiens	90.31	1.00e-118	418.00
IUUC-Itr-048397	Ictidomys tridecemlineatus	94.94	4.00e-137	480.00
IUUC-Lch-050555	Latimeria chalumnae	55.94	3.00e-71	261.00
IUUC-Loc-051825	Lepisosteus oculatus	42.11	1.00e-40	159.00
IUUC-Laf-054141	Loxodonta africana	90.70	6.00e-129	452.00
IUUC-Mcc-055401	Macaca mulatta	89.64	5.00e-112	396.00
IUUC-Meu-056592	Macropus eugenii	69.32	2.00e-89	321.00
IUUC-Mga-059515	Meleagris gallopavo	64.98	5.00e-79	286.00
IUUC-Mmr-060848	Microcebus murinus	96.00	9.00e-123	432.00
IUUC-Mdo-062720	Monodelphis domestica	68.09	2.00e-90	324.00
IUUC-Mmu-063348	Mus musculus	91.83	2.00e-131	461.00
IUUC-Mpu-065834	Mustela putorius furo	94.55	4.00e-129	453.00
IUUC-Mlu-067687	Myotis lucifugus	89.49	6.00e-108	382.00
IUUC-Nle-069277	Nomascus leucogenys	90.31	2.00e-116	411.00
IUUC-Opr-071087	Ochotona princeps	41.43	5.00e-39	153.00
IUUC-Ont-071890	Oreochromis niloticus	46.60	9.00e-37	146.00
IUUC-Oan-073672	Ornithorhynchus anatinus	65.25	9.00e-87	312.00
IUUC-Ocu-073875	Oryctolagus cuniculus	93.20	5.00e-128	449.00
IUUC-Ola-087140	Oryzias latipes	45.10	6.00e-25	106.00
IUUC-Oga-087943	Otolemur garnettii	92.61	8.00e-128	449.00
IUUC-Oar-090194	Ovis aries	91.67	7.00e-128	449.00
IUUC-Ptr-090934	Pan troglodytes	89.64	9.00e-113	399.00
IUUC-Pan-092121	Papio anubis	89.92	9.00e-117	412.00
IUUC-Psi-093733	Pelodiscus sinensis	61.90	6.00e-83	300.00
IUUC-Pma-094671	Petromyzon marinus	35.38	3.00e-32	131.00
IUUC-Pfo-096313	Poecilia formosa	44.95	1.00e-43	168.00
IUUC-Pab-098439	Pongo abelii	90.31	5.00e-118	416.00
IUUC-Pca-101010	Procavia capensis	91.09	5.00e-129	453.00
IUUC-Pva-103112	Pteropus vampyrus	93.39	4.00e-124	436.00
IUUC-Rno-105917	Rattus norvegicus	92.22	3.00e-124	437.00
IUUC-Sha-106954	Sarcophilus harrisii	66.92	4.00e-91	327.00
IUUC-Smo-109292	Selaginella moellendorffii	31.15	1.70e-01	30.80
IUUC-Sar-113001	Sorex araneus	94.40	3.00e-125	440.00
IUUC-Ssc-115922	Sus scrofa	94.33	3.00e-68	249.00
IUUC-Tgu-117338	Taeniopygia guttata	65.22	3.00e-84	304.00
IUUC-Tru-118511	Takifugu rubripes	44.51	9.00e-34	136.00
IUUC-Tsy-119434	Tarsius syrichta	92.80	4.00e-119	420.00
IUUC-Tni-119837	Tetraodon nigroviridis	43.37	1.00e-29	122.00
IUUC-Tbe-127915	Tupaia belangeri	43.58	2.00e-38	152.00
IUUC-Ttr-128340	Tursiops truncatus	80.54	6.00e-86	309.00
IUUC-Vpa-130443	Vicugna pacos	93.77	5.00e-133	466.00
IUUC-Xtr-131784	Xenopus tropicalis	50.72	3.00e-68	251.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence