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Tag Content
UUCD2 ID IUUC-Sha-107489
UUCD1 version UUC-SaH-01067
Ensembl Protein ID ENSSHAP00000014815.1
UniProt Accession G3WHB0; G3WHB0_SARHA
Genbank Protein ID ENSSHAP00000014815
Protein Name Uncharacterized protein
Genbank Nucleotide ID AEFK01114675
Gene Name USP28
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSHAG00000012648.1 ENSSHAT00000014940.1 ENSSHAP00000014815.1
ENSSHAG00000012648.1 ENSSHAT00000014941.1 ENSSHAP00000014816.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 5.90e-58 196.8 143 628
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeef 84
           +GlkN+gNtC++ +v+Q+L++++e+r+l+l      +  e+++    ++++  ++++lq lf+ ++ s++k v+p++ l+ lk + ++ 
   Q: 143  VGLKNVGNTCWFSAVIQSLFQLSEFRRLVLGyslpqNILENCRSH-TEKRNIVFMQELQYLFALMMGSNRKFVDPSAALDLLKGAFRS- 229
           6******************************96665455555443.478888*******************************99998. PP
   S: 85   sgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
              +qqD++Ef++ lld le+++                 +l  + ++++ +k+++++++lF g++ ++ + +  +++   +e+f +++
   Q: 230  ADEQQQDVSEFTHKLLDWLEDAF-----------------QLAVNVNSSPRNKSENPMVQLFYGTFLTEGVHE--GKTFCNNETFGQYP 299
           789********************.................566677899******************999985..45556699****** PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls 262
           l+v+g +     +l++cLe  + e e+e    +  +   ++++  ++ +++klP+vL+++L+Rf+f+++ +++eki++k+efp+ + ++
   Q: 300  LQVNGYR-----NLDECLEGAMVEGEIE----MLPPD--HSVKYGQERWFTKLPPVLTFELSRFEFNQSLGQPEKIHNKLEFPQIIYMD 377
           *******.....9*****9998888888....44444..3455678889**************************************** PP
   S: 263  pfcts.................................................................................... 267
           +++ s                                                                                    
   Q: 378  RYMYSskelirtkrehirklkeevkvlqqkleryvkygsgparfplpdmlqyvlefastkpaeevppsghasslhcpisdltakksira 466
           *9999777777777777777777777777777777777776666666666666666666666666666666666666655555555555 PP
   S: 268  .peekqke................................................................................. 274
            +                                                                                       
   Q: 467  eE-----Ysgkvevslsslekenllqsdlinkpftssrpsvkmpehpaprtiteeemnfvktclqrwrseieqdiqdlknciatttqti 550
           50.....0555555555555555666666666666666666677777777777777777788888888888888888888899999999 PP
   S: 275  ..........kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                     ++ Y+L+av+vH+G+++ GHY+ay++n+ ++ Wl+++D +Vte+++ee ++++       +aY+l+Y 
   Q: 551  eqmysdpllhQVPYRLHAVLVHEGQANAGHYWAYIYNRPRNiWLKYNDISVTESSWEELERDSYgglrnVSAYCLMYI 628
           9999999999***************************88888*******************8879************6 PP
   
Organism Sarcophilus harrisii
Protein Sequence
(Fasta)
SCQMLLNQLR EITGIQDPSF LHEALKASNG DITQAVSLLT DERVKEPSQD TIAAEPSEGE 60
GSAANKVVPT KVIDPTHDNK DDLQAAIALS LLESPKIQAD GRDHNRTHEA ATVENKRSKR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sha-107489|DUB,USP|Sarcophilus harrisii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGCTGCCAAA TGCTATTAAA TCAACTGAGA GAAATCACTG GAATTCAGGA TCCATCTTTT 60
CTTCATGAAG CTTTGAAGGT TAGTTTAAAG AGTCTTTTAA GCAATTACAT TTAGAGAAGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sha-107489|DUB,USP|Sarcophilus harrisii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
Gene Ontology

GO:0016604--C:nuclear body
GO:0043234--C:protein complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008283--P:cell proliferation
GO:0034644--P:cellular response to UV
GO:0000077--P:DNA damage checkpoint
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0016579--P:protein deubiquitination
GO:0007265--P:Ras protein signal transduction
GO:0031647--P:regulation of protein stability
GO:0010212--P:response to ionizing radiation
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001836 Ailuropoda melanoleuca 87.43 0.00e+00 1883.00
IUUC-Apl-004010 Anas platyrhynchos 70.00 0.00e+00 1495.00
IUUC-Aca-004741 Anolis carolinensis 59.95 0.00e+00 847.00
IUUC-Acl-008164 Aspergillus clavatus 24.82 3.00e-16 80.90
IUUC-Afl-008717 Aspergillus flavus 43.06 1.00e-09 59.30
IUUC-Ani-009503 Aspergillus nidulans 38.68 2.00e-12 67.80
IUUC-Ang-009577 Aspergillus niger 37.37 4.00e-12 67.40
IUUC-Ate-010275 Aspergillus terreus 33.33 5.00e-11 63.50
IUUC-Bgr-011993 Blumeria graminis 41.89 7.00e-13 70.10
IUUC-Bta-013377 Bos taurus 85.08 0.00e+00 1785.00
IUUC-Cja-019977 Callithrix jacchus 87.71 0.00e+00 1861.00
IUUC-Cfa-020378 Canis familiaris 85.26 0.00e+00 1279.00
IUUC-Cpo-021817 Cavia porcellus 84.90 0.00e+00 1809.00
IUUC-Csa-023446 Chlorocebus sabaeus 85.22 0.00e+00 1259.00
IUUC-Cho-024717 Choloepus hoffmanni 75.72 0.00e+00 1133.00
IUUC-Csv-025911 Ciona savignyi 33.76 2.00e-143 502.00
IUUC-Dre-028105 Danio rerio 57.72 0.00e+00 720.00
IUUC-Dno-029559 Dasypus novemcinctus 82.32 0.00e+00 1394.00
IUUC-Dor-030955 Dipodomys ordii 84.33 0.00e+00 1788.00
IUUC-Ete-032828 Echinops telfairi 75.93 0.00e+00 1085.00
IUUC-Eca-034300 Equus caballus 87.04 0.00e+00 1817.00
IUUC-Eeu-034458 Erinaceus europaeus 82.97 0.00e+00 1599.00
IUUC-Fca-035753 Felis catus 87.51 0.00e+00 1878.00
IUUC-Fal-037062 Ficedula albicollis 64.13 0.00e+00 894.00
IUUC-Gmo-039593 Gadus morhua 52.39 0.00e+00 1034.00
IUUC-Gga-040878 Gallus gallus 65.86 0.00e+00 1345.00
IUUC-Gac-041867 Gasterosteus aculeatus 55.57 0.00e+00 1130.00
IUUC-Ggo-045384 Gorilla gorilla 87.52 0.00e+00 1853.00
IUUC-Hsa-046277 Homo sapiens 87.52 0.00e+00 1848.00
IUUC-Itr-048276 Ictidomys tridecemlineatus 79.33 0.00e+00 1056.00
IUUC-Lch-049692 Latimeria chalumnae 67.89 0.00e+00 1420.00
IUUC-Laf-053808 Loxodonta africana 80.49 0.00e+00 1700.00
IUUC-Mcc-055473 Macaca mulatta 85.22 0.00e+00 1259.00
IUUC-Meu-056416 Macropus eugenii 84.34 0.00e+00 1728.00
IUUC-Mga-060011 Meleagris gallopavo 68.19 0.00e+00 1423.00
IUUC-Mmr-060720 Microcebus murinus 85.15 0.00e+00 1769.00
IUUC-Mdo-061955 Monodelphis domestica 96.80 0.00e+00 1472.00
IUUC-Mmu-063870 Mus musculus 81.43 0.00e+00 1732.00
IUUC-Mpu-066454 Mustela putorius furo 83.93 0.00e+00 1229.00
IUUC-Mlu-067487 Myotis lucifugus 82.01 0.00e+00 1739.00
IUUC-Nle-070044 Nomascus leucogenys 87.34 0.00e+00 1845.00
IUUC-Opr-070888 Ochotona princeps 91.34 3.00e-149 522.00
IUUC-Ont-072386 Oreochromis niloticus 56.05 0.00e+00 746.00
IUUC-Ocu-074523 Oryctolagus cuniculus 84.90 0.00e+00 1800.00
IUUC-Ola-086393 Oryzias latipes 55.42 0.00e+00 1128.00
IUUC-Oga-088618 Otolemur garnettii 85.37 0.00e+00 1807.00
IUUC-Oar-089848 Ovis aries 81.70 0.00e+00 1204.00
IUUC-Ptr-091630 Pan troglodytes 85.49 0.00e+00 1395.00
IUUC-Psi-093422 Pelodiscus sinensis 65.78 0.00e+00 1413.00
IUUC-Pma-094250 Petromyzon marinus 50.38 4.00e-70 257.00
IUUC-Pno-095093 Phaeosphaeria nodorum 31.86 7.00e-13 69.70
IUUC-Pfo-096466 Poecilia formosa 56.55 0.00e+00 765.00
IUUC-Pab-098337 Pongo abelii 87.34 0.00e+00 1842.00
IUUC-Pca-100901 Procavia capensis 88.01 0.00e+00 979.00
IUUC-Pva-102226 Pteropus vampyrus 81.41 0.00e+00 1599.00
IUUC-Rno-105735 Rattus norvegicus 78.44 0.00e+00 1736.00
IUUC-Ssl-108532 Sclerotinia sclerotiorum 34.57 6.00e-10 60.10
IUUC-Tgu-116609 Taeniopygia guttata 69.01 0.00e+00 1417.00
IUUC-Tru-117807 Takifugu rubripes 54.93 0.00e+00 1091.00
IUUC-Tsy-118971 Tarsius syrichta 81.26 0.00e+00 1152.00
IUUC-Tni-119983 Tetraodon nigroviridis 55.26 0.00e+00 1109.00
IUUC-Ttr-128887 Tursiops truncatus 81.52 0.00e+00 1682.00
IUUC-Uma-129338 Ustilago maydis 24.00 2.00e-11 65.50
IUUC-Vpa-130614 Vicugna pacos 85.73 0.00e+00 1386.00
Created Date 25-Jun-2017

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