iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052038

Ensembl Protein ID

ENSLOCP00000011043.1

UniProt Accession

W5MRN4; W5MRN4_LEPOC

Genbank Protein ID

ENSLOCP00000011043

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AHAT01003442

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000009063.1	ENSLOCT00000011059.1	ENSLOCP00000011043.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	4.70e-09	36.5	206	253

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 206  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 253
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

IHVANYVEEY LDLVESLPFD LQRNVSLMRE IDAKYQGVSE ILKELDEIYE KHKKEGDPVQ 60
KKRLLHCIQR ALIRSQELGD EKIQIVSQMV ELVENRSRQV EGHVEFLEAS QEPSESLVVP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCCACGTTG CTAACTATGT GGAGGAGTAT TTAGACTTGG TCGAATCGTT GCCTTTCGAC 60
TTGCAGCGAA ATGTGTCGCT GATGAGGGAA ATCGACGCTA AATACCAAGG TAAGCTTCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0010941--P:regulation of cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	82.17	1.00e-96	345.00
IUUC-Apl-003910	Anas platyrhynchos	79.46	2.00e-94	338.00
IUUC-Aca-004874	Anolis carolinensis	79.46	2.00e-93	335.00
IUUC-Ame-011262	Astyanax mexicanus	73.13	4.00e-94	337.00
IUUC-Bta-013507	Bos taurus	79.00	1.00e-69	255.00
IUUC-Cja-018925	Callithrix jacchus	77.13	7.00e-91	326.00
IUUC-Cfa-020947	Canis familiaris	82.56	6.00e-96	343.00
IUUC-Cpo-022286	Cavia porcellus	81.00	3.00e-76	278.00
IUUC-Csa-023825	Chlorocebus sabaeus	77.52	1.00e-90	325.00
IUUC-Cho-024577	Choloepus hoffmanni	81.65	3.00e-77	280.00
IUUC-Cne-027005	Cryptococcus neoformans	53.57	2.00e-15	76.60
IUUC-Dre-028562	Danio rerio	63.08	8.00e-70	256.00
IUUC-Dno-029834	Dasypus novemcinctus	82.17	1.00e-96	345.00
IUUC-Dor-030315	Dipodomys ordii	80.91	3.00e-86	311.00
IUUC-Ete-032408	Echinops telfairi	77.23	1.00e-70	259.00
IUUC-Eca-034244	Equus caballus	80.82	4.00e-76	277.00
IUUC-Eeu-035285	Erinaceus europaeus	59.30	1.00e-48	185.00
IUUC-Fca-035391	Felis catus	79.23	4.00e-93	333.00
IUUC-Fal-036838	Ficedula albicollis	79.07	7.00e-94	336.00
IUUC-Fox-037925	Fusarium oxysporum	69.57	1.00e-19	90.90
IUUC-Gmo-038748	Gadus morhua	54.65	3.00e-68	251.00
IUUC-Gga-040619	Gallus gallus	80.23	3.00e-95	340.00
IUUC-Gac-041996	Gasterosteus aculeatus	64.34	3.00e-85	308.00
IUUC-Ggo-045481	Gorilla gorilla	76.26	9.00e-72	263.00
IUUC-Hsa-046170	Homo sapiens	72.22	5.00e-72	265.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	81.28	2.00e-76	278.00
IUUC-Lch-050397	Latimeria chalumnae	82.56	2.00e-98	351.00
IUUC-Laf-054126	Loxodonta africana	81.01	2.00e-95	342.00
IUUC-Mcc-055031	Macaca mulatta	77.17	7.00e-72	264.00
IUUC-Meu-056248	Macropus eugenii	78.95	8.00e-77	280.00
IUUC-Mga-059217	Meleagris gallopavo	79.02	2.00e-76	278.00
IUUC-Mmr-061581	Microcebus murinus	80.52	3.00e-80	291.00
IUUC-Mdo-062452	Monodelphis domestica	81.40	5.00e-96	343.00
IUUC-Mmu-063412	Mus musculus	80.62	4.00e-94	337.00
IUUC-Mpu-066479	Mustela putorius furo	82.27	1.00e-78	286.00
IUUC-Mlu-067586	Myotis lucifugus	69.77	2.00e-91	328.00
IUUC-Nle-069122	Nomascus leucogenys	77.13	6.00e-91	327.00
IUUC-Opr-070835	Ochotona princeps	76.15	5.00e-68	250.00
IUUC-Ont-071606	Oreochromis niloticus	63.48	5.00e-80	290.00
IUUC-Oan-073023	Ornithorhynchus anatinus	79.46	2.00e-92	332.00
IUUC-Ocu-073779	Oryctolagus cuniculus	81.82	1.00e-76	278.00
IUUC-Ola-086891	Oryzias latipes	66.41	4.00e-85	307.00
IUUC-Olu-087851	Ostreococcus lucimarinus	69.23	1.00e-19	89.40
IUUC-Oga-087954	Otolemur garnettii	80.62	8.00e-95	339.00
IUUC-Oar-090006	Ovis aries	79.07	3.00e-92	330.00
IUUC-Ptr-090589	Pan troglodytes	76.74	1.00e-90	325.00
IUUC-Pan-091896	Papio anubis	73.08	4.00e-72	265.00
IUUC-Psi-093266	Pelodiscus sinensis	81.78	2.00e-96	345.00
IUUC-Pma-094265	Petromyzon marinus	79.66	1.00e-29	122.00
IUUC-Pfo-097531	Poecilia formosa	63.48	3.00e-85	308.00
IUUC-Pab-098253	Pongo abelii	76.74	3.00e-90	324.00
IUUC-Pop-099415	Populus trichocarpa	76.36	1.00e-25	109.00
IUUC-Pca-100278	Procavia capensis	58.50	3.00e-66	244.00
IUUC-Pva-102753	Pteropus vampyrus	72.36	2.00e-66	246.00
IUUC-Rno-105964	Rattus norvegicus	80.82	5.00e-71	260.00
IUUC-Sha-107270	Sarcophilus harrisii	81.78	7.00e-97	346.00
IUUC-Sar-113630	Sorex araneus	59.30	2.00e-48	185.00
IUUC-Ssc-115734	Sus scrofa	59.68	1.00e-59	223.00
IUUC-Tgu-116822	Taeniopygia guttata	79.07	6.00e-94	337.00
IUUC-Tru-118262	Takifugu rubripes	55.56	1.00e-69	256.00
IUUC-Tsy-119494	Tarsius syrichta	58.60	4.00e-44	170.00
IUUC-Tni-119980	Tetraodon nigroviridis	59.93	1.00e-73	269.00
IUUC-Tvi-122341	Trichoderma virens	62.50	3.00e-16	77.80
IUUC-Ttr-128672	Tursiops truncatus	80.82	2.00e-75	275.00
IUUC-Vpa-130063	Vicugna pacos	60.08	1.00e-60	226.00
IUUC-Xtr-132200	Xenopus tropicalis	77.91	4.00e-89	320.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence