iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088937

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03121160

Gene Name

TRIM25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000003870.2	ENSOGAT00000003873.2	ENSOGAP00000003441.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.40e-08	34.4	13	54

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCle+fk+ p+++pCgH f+ +Cl + w        +  +CP Cr
   Q: 13   CSICLEPFKE-PVTTPCGHNFCGSCLnETW----AGPGGPYLCPHCR 54
           ********99.***************99**....7778999*****8 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MAELYPLADE LSCSICLEPF KEPVTTPCGH NFCGSCLNET WAGPGGPYLC PHCRAVYHSR 60
PQLRKNTVLC AVVEQFLQAE LAREAPADEW TPPARAAAPT SGVWVACDHC LKEAAVKTCL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAGC TGTACCCCCT GGCCGACGAG CTGTCATGCT CCATCTGTCT GGAGCCCTTC 60
AAGGAGCCGG TCACCACCCC GTGCGGCCAC AACTTCTGCG GGTCGTGCCT GAACGAGACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0003723--F:RNA binding
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0006513--P:protein monoubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002424	Ailuropoda melanoleuca	69.91	0.00e+00	863.00
IUUC-Apl-004101	Anas platyrhynchos	46.03	6.00e-151	527.00
IUUC-Aca-005025	Anolis carolinensis	45.12	2.00e-157	549.00
IUUC-Bta-012735	Bos taurus	69.91	0.00e+00	850.00
IUUC-Cja-019996	Callithrix jacchus	66.45	1.00e-158	552.00
IUUC-Cfa-020466	Canis familiaris	66.82	0.00e+00	837.00
IUUC-Cpo-021737	Cavia porcellus	63.27	0.00e+00	793.00
IUUC-Csa-023217	Chlorocebus sabaeus	74.17	0.00e+00	922.00
IUUC-Cho-024346	Choloepus hoffmanni	48.68	1.00e-68	253.00
IUUC-Dno-030082	Dasypus novemcinctus	67.72	0.00e+00	845.00
IUUC-Dor-030335	Dipodomys ordii	45.63	3.00e-97	348.00
IUUC-Ete-032923	Echinops telfairi	62.31	0.00e+00	700.00
IUUC-Eca-033411	Equus caballus	69.75	0.00e+00	866.00
IUUC-Eeu-034656	Erinaceus europaeus	75.16	2.00e-140	493.00
IUUC-Fca-035371	Felis catus	68.60	0.00e+00	857.00
IUUC-Fal-037008	Ficedula albicollis	45.70	4.00e-152	531.00
IUUC-Gmo-038668	Gadus morhua	35.57	9.00e-106	377.00
IUUC-Gga-040608	Gallus gallus	46.74	6.00e-150	524.00
IUUC-Gac-041409	Gasterosteus aculeatus	37.62	2.00e-56	213.00
IUUC-Ggo-044518	Gorilla gorilla	74.45	0.00e+00	894.00
IUUC-Hsa-045828	Homo sapiens	75.08	0.00e+00	920.00
IUUC-Itr-049070	Ictidomys tridecemlineatus	63.54	0.00e+00	775.00
IUUC-Lch-050478	Latimeria chalumnae	42.95	2.00e-68	253.00
IUUC-Loc-052864	Lepisosteus oculatus	36.60	5.00e-112	398.00
IUUC-Laf-054325	Loxodonta africana	76.05	3.00e-142	498.00
IUUC-Mcc-054920	Macaca mulatta	74.17	0.00e+00	922.00
IUUC-Meu-056367	Macropus eugenii	71.18	6.00e-74	271.00
IUUC-Mga-059975	Meleagris gallopavo	46.10	2.00e-148	519.00
IUUC-Mmr-060748	Microcebus murinus	80.53	0.00e+00	967.00
IUUC-Mdo-062904	Monodelphis domestica	54.43	0.00e+00	639.00
IUUC-Mmu-063891	Mus musculus	66.72	0.00e+00	848.00
IUUC-Mpu-066473	Mustela putorius furo	69.15	0.00e+00	875.00
IUUC-Mlu-068185	Myotis lucifugus	70.35	0.00e+00	847.00
IUUC-Nle-070177	Nomascus leucogenys	73.82	0.00e+00	909.00
IUUC-Opr-070558	Ochotona princeps	54.10	1.00e-124	439.00
IUUC-Ocu-074461	Oryctolagus cuniculus	51.31	3.00e-162	565.00
IUUC-Ola-087180	Oryzias latipes	29.37	4.00e-61	229.00
IUUC-Oar-089781	Ovis aries	65.92	2.00e-157	548.00
IUUC-Ptr-090771	Pan troglodytes	75.12	0.00e+00	909.00
IUUC-Pan-092830	Papio anubis	74.49	0.00e+00	925.00
IUUC-Psi-093664	Pelodiscus sinensis	49.20	2.00e-163	568.00
IUUC-Pma-094147	Petromyzon marinus	27.37	5.00e-63	235.00
IUUC-Pfo-096528	Poecilia formosa	34.81	5.00e-111	394.00
IUUC-Pab-097588	Pongo abelii	73.47	0.00e+00	899.00
IUUC-Pca-100890	Procavia capensis	73.79	7.00e-133	467.00
IUUC-Pva-102314	Pteropus vampyrus	73.06	0.00e+00	866.00
IUUC-Pgr-103377	Puccinia graminis	35.71	2.00e-05	44.30
IUUC-Ptt-103758	Puccinia triticina	37.50	1.00e-05	43.50
IUUC-Rno-105234	Rattus norvegicus	73.46	6.00e-138	484.00
IUUC-Sce-106362	Saccharomyces cerevisiae	43.48	8.00e-09	54.70
IUUC-Sha-106807	Sarcophilus harrisii	50.30	8.00e-176	610.00
IUUC-Sar-113283	Sorex araneus	67.11	2.00e-111	395.00
IUUC-Ssc-115878	Sus scrofa	80.00	2.00e-105	374.00
IUUC-Tgu-117026	Taeniopygia guttata	44.27	4.00e-119	421.00
IUUC-Tbe-127580	Tupaia belangeri	72.49	2.00e-125	441.00
IUUC-Ttr-128648	Tursiops truncatus	79.82	4.00e-113	401.00
IUUC-Vpa-130254	Vicugna pacos	84.97	1.00e-92	333.00
IUUC-Xtr-132892	Xenopus tropicalis	43.32	4.00e-66	244.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence