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Tag Content
iUUCD ID IUUC-Ont-072044
Ensembl Protein ID ENSONIP00000009702.1
UniProt Accession I3JLF8; I3JLF8_ORENI
Genbank Protein ID ENSONIP00000009702
Protein Name Uncharacterized protein
Genbank Nucleotide ID AERX01026657
Gene Name nedd4l
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSONIG00000007697.1 ENSONIT00000009708.1 ENSONIP00000009702.1
ENSONIG00000007697.1 ENSONIT00000009709.1 ENSONIP00000009703.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 1.20e-135 452.7 684 1015
Active Site
Position(s) Description Evidence
985 Glycyl thioester intermediate {ECO:0000256|PIRSR:PIRSR001569-1,
ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrll 88
           ++ lk+rl++ef+ E+gld+gGv+re+++llske++np++glf+ys++d++tlq+np+sgl+n++hl++F+f+Gr+ g+a+++g+ll
   Q: 684  PDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVFHGKLL 770
           57899********************************************************************************** PP
   S: 89   dlplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvk 175
           d ++ ++fyk++lgk++sl+d+e+vd+e+y+slk+i+en   d +e  ldl+f+++e+++g+t++++Lkp+G+++ Vtn+Nk+eY++
   Q: 771  DGFFIRPFYKMMLGKQISLKDMESVDSEYYNSLKWILEN---DPTE--LDLRFCIDEDNFGQTYQVDLKPSGSDMVVTNDNKKEYID 852
           *************************************99...6666..7************************************** PP
   S: 176  lvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerk 262
           lv+++r+ +++++q++af eGf+e+i+++l+++F+e+elell+cG  ++dv+d++++t yk+gy +++p+iqwFw+v+  +++e+r 
   Q: 853  LVIQWRFVNRVQKQMNAFLEGFTELIQIDLIKIFDENELELLMCGLGDVDVNDWRQHTVYKNGYCPNHPVIQWFWKVVLLMDAEKRI 939
           *************************************************************************************** PP
   S: 263  afLqFvTgssrlPlgGfaelk....prlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
           ++LqFvTg+sr+P++Gfael     p+lf+i++++++d+lP+++TCfn+L+LP+Y+s e l+ekLl+A+e+++gFe
   Q: 940  RLLQFVTGTSRVPMNGFAELYgsngPQLFTIEQWGTPDKLPRAHTCFNRLDLPTYESFEDLREKLLMAVENAQGFE 1015
           ***************************************************************************8 PP
   
Organism Oreochromis niloticus
Protein Sequence
(Fasta)
MAANYEPIYG LSEDEHETRV LRVKVIAGID LAKKDILGAS DPYVKLSLYV ADETRELALV 60
QTKTIKKTLN PKWNEEFYFR VCPQNHRLLF EVFDENRLAT SKNGLFHLGQ TRDDFLGQVD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ont-072044|E3,HECT|Oreochromis niloticus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CAACAGTGAG ACATGGTTAT ACATAACATA AAAAGAGCGA GAAAAATATA AACGACCCAC 60
TTAATTTACA CGTCCTCTTC TTATTTAATT GGCCAGCCAG GAGCGTTAGG GAAATTCAAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ont-072044|E3,HECT|Oreochromis niloticus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom
PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2
Pfam

PF00168--C2
PF00632--HECT
PF00397--WW
PRINTS

PR00360--C2DOMAIN
SMART

SM00239--C2
SM00119--HECTc
SM00456--WW
Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001314 Ailuropoda melanoleuca 76.49 0.00e+00 1405.00
IUUC-Apl-003893 Anas platyrhynchos 78.05 0.00e+00 1453.00
IUUC-Aca-004744 Anolis carolinensis 75.75 0.00e+00 1401.00
IUUC-Aor-010053 Aspergillus oryzae 57.38 3.00e-100 358.00
IUUC-Ame-010810 Astyanax mexicanus 89.38 0.00e+00 1080.00
IUUC-Bta-012679 Bos taurus 77.84 0.00e+00 1322.00
IUUC-Cja-018732 Callithrix jacchus 78.30 0.00e+00 1500.00
IUUC-Cfa-021226 Canis familiaris 78.05 0.00e+00 1484.00
IUUC-Cpo-021671 Cavia porcellus 76.73 0.00e+00 1453.00
IUUC-Csa-023344 Chlorocebus sabaeus 76.49 0.00e+00 1481.00
IUUC-Cho-024832 Choloepus hoffmanni 94.32 0.00e+00 714.00
IUUC-Dre-027770 Danio rerio 85.24 0.00e+00 1569.00
IUUC-Dno-029466 Dasypus novemcinctus 77.84 0.00e+00 1492.00
IUUC-Dor-030138 Dipodomys ordii 74.49 0.00e+00 1362.00
IUUC-Dme-032166 Drosophila melanogaster 68.34 0.00e+00 719.00
IUUC-Ete-033145 Echinops telfairi 72.07 0.00e+00 1058.00
IUUC-Eca-033445 Equus caballus 77.88 0.00e+00 1312.00
IUUC-Eeu-035247 Erinaceus europaeus 76.31 0.00e+00 1176.00
IUUC-Fca-035489 Felis catus 75.81 0.00e+00 1262.00
IUUC-Fal-037604 Ficedula albicollis 75.34 0.00e+00 1476.00
IUUC-Gmo-039674 Gadus morhua 83.56 0.00e+00 1567.00
IUUC-Gga-040703 Gallus gallus 78.03 0.00e+00 1507.00
IUUC-Gac-042020 Gasterosteus aculeatus 89.81 0.00e+00 1660.00
IUUC-Ggo-045332 Gorilla gorilla 76.82 0.00e+00 1420.00
IUUC-Hsa-045968 Homo sapiens 77.84 0.00e+00 1492.00
IUUC-Lch-050443 Latimeria chalumnae 79.36 0.00e+00 1339.00
IUUC-Loc-052662 Lepisosteus oculatus 82.62 0.00e+00 1532.00
IUUC-Laf-053850 Loxodonta africana 77.11 0.00e+00 1464.00
IUUC-Mcc-055821 Macaca mulatta 77.90 0.00e+00 1474.00
IUUC-Meu-056712 Macropus eugenii 59.77 8.00e-166 578.00
IUUC-Mga-059264 Meleagris gallopavo 62.07 0.00e+00 895.00
IUUC-Mvi-060395 Microbotryum violaceum 54.94 7.00e-153 534.00
IUUC-Mmr-060798 Microcebus murinus 73.81 0.00e+00 1361.00
IUUC-Mdo-062173 Monodelphis domestica 76.80 0.00e+00 1501.00
IUUC-Mmu-064136 Mus musculus 77.06 0.00e+00 1471.00
IUUC-Mpu-066765 Mustela putorius furo 78.32 0.00e+00 1466.00
IUUC-Mlu-067565 Myotis lucifugus 77.52 0.00e+00 1317.00
IUUC-Nle-069070 Nomascus leucogenys 75.29 0.00e+00 1421.00
IUUC-Opr-071044 Ochotona princeps 82.05 0.00e+00 1077.00
IUUC-Oan-073032 Ornithorhynchus anatinus 74.12 0.00e+00 1186.00
IUUC-Ocu-074160 Oryctolagus cuniculus 76.58 0.00e+00 1447.00
IUUC-Ola-087467 Oryzias latipes 89.76 0.00e+00 1701.00
IUUC-Oga-088460 Otolemur garnettii 76.23 0.00e+00 1303.00
IUUC-Oar-090198 Ovis aries 77.82 0.00e+00 1462.00
IUUC-Ptr-090939 Pan troglodytes 77.84 0.00e+00 1492.00
IUUC-Pan-092284 Papio anubis 77.94 0.00e+00 1491.00
IUUC-Psi-093645 Pelodiscus sinensis 77.75 0.00e+00 1484.00
IUUC-Pma-094364 Petromyzon marinus 82.74 0.00e+00 838.00
IUUC-Pfo-096768 Poecilia formosa 98.71 0.00e+00 1020.00
IUUC-Pab-098088 Pongo abelii 77.64 0.00e+00 1479.00
IUUC-Pca-100714 Procavia capensis 63.20 0.00e+00 1088.00
IUUC-Pva-102354 Pteropus vampyrus 76.24 0.00e+00 1396.00
IUUC-Pgr-103620 Puccinia graminis 53.53 4.00e-148 518.00
IUUC-Ptt-103806 Puccinia triticina 53.86 2.00e-124 440.00
IUUC-Rno-105318 Rattus norvegicus 76.41 0.00e+00 1437.00
IUUC-Sha-107482 Sarcophilus harrisii 78.18 0.00e+00 1360.00
IUUC-Ssc-115950 Sus scrofa 62.75 0.00e+00 1052.00
IUUC-Tgu-117130 Taeniopygia guttata 77.80 0.00e+00 1492.00
IUUC-Tru-118610 Takifugu rubripes 90.52 0.00e+00 1749.00
IUUC-Tsy-119492 Tarsius syrichta 73.56 0.00e+00 1327.00
IUUC-Tni-120113 Tetraodon nigroviridis 83.85 0.00e+00 1578.00
IUUC-Ttr-128235 Tursiops truncatus 90.76 0.00e+00 994.00
IUUC-Xtr-132859 Xenopus tropicalis 77.04 0.00e+00 1457.00
IUUC-Xma-133797 Xiphophorus maculatus 89.95 0.00e+00 1699.00
Created Date 25-Jun-2017

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