iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033679

Ensembl Protein ID

ENSECAP00000011179.1

UniProt Accession

F7BCY9; F7BCY9_HORSE

Protein Name

Uncharacterized protein

Gene Name

PACSIN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000013077.1	ENSECAT00000014028.1	ENSECAP00000011179.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.50e-15	55.9	391	446

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +v++lydy++q++deL++k+Gd ++ +  ee ++gW++g + ++g+ Gl P+n+ve +
   Q: 391  RVRALYDYDGQEQDELSFKAGDELTKL-GEEDEQGWCRG-RLDSGQLGLYPANYVEAI 446
           699************************.***********.59*************975 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MSGSYDEASL APEETTDSFW EEIMWGNYKR TVKRIDDGHR LCDLMNCKSP QNYVPLTQIH 60
QLTFYHVGWE QMTVECPQYG SLERAWGAIM TEADKVSELH QEVKNSLLNE DLEKVKNWQK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCGGCT CCTACGATGA GGCCTCGCTA GCTCCGGAGG AGACCACTGA CAGCTTCTGG 60
GAGGTGAGGC TTCAATGTTC CCCATGTCCT GGGGATCACA CAGCCTGGCC ATGTGGAGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR028518--PACSIN1
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0030137--C:COPI-coated vesicle
GO:0005768--C:endosome
GO:0043209--C:myelin sheath
GO:0032587--C:ruffle membrane
GO:0045202--C:synapse
GO:0005543--F:phospholipid binding
GO:0007015--P:actin filament organization
GO:0045806--P:negative regulation of endocytosis
GO:0048812--P:neuron projection morphogenesis
GO:0097320--P:plasma membrane tubulation
GO:0072657--P:protein localization to membrane
GO:0030100--P:regulation of endocytosis
GO:0048488--P:synaptic vesicle endocytosis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001861	Ailuropoda melanoleuca	83.10	0.00e+00	710.00
IUUC-Apl-003667	Anas platyrhynchos	80.19	0.00e+00	637.00
IUUC-Aca-005229	Anolis carolinensis	75.50	0.00e+00	651.00
IUUC-Bta-013509	Bos taurus	90.38	0.00e+00	697.00
IUUC-Cja-019659	Callithrix jacchus	90.16	0.00e+00	753.00
IUUC-Cfa-020396	Canis familiaris	91.95	0.00e+00	736.00
IUUC-Cpo-022376	Cavia porcellus	89.93	0.00e+00	721.00
IUUC-Csa-023701	Chlorocebus sabaeus	90.60	0.00e+00	724.00
IUUC-Dre-027456	Danio rerio	69.78	2.00e-175	608.00
IUUC-Fca-036314	Felis catus	91.72	0.00e+00	735.00
IUUC-Fal-037300	Ficedula albicollis	79.29	0.00e+00	674.00
IUUC-Gmo-038571	Gadus morhua	63.30	2.00e-144	505.00
IUUC-Gga-040626	Gallus gallus	80.62	0.00e+00	633.00
IUUC-Ggo-045557	Gorilla gorilla	90.38	0.00e+00	723.00
IUUC-Hsa-045778	Homo sapiens	90.38	0.00e+00	723.00
IUUC-Itr-048856	Ictidomys tridecemlineatus	89.93	0.00e+00	723.00
IUUC-Loc-051764	Lepisosteus oculatus	74.00	0.00e+00	630.00
IUUC-Laf-054465	Loxodonta africana	89.06	0.00e+00	734.00
IUUC-Mcc-055324	Macaca mulatta	90.38	0.00e+00	725.00
IUUC-Meu-056348	Macropus eugenii	85.01	0.00e+00	677.00
IUUC-Mga-059285	Meleagris gallopavo	81.37	1.00e-180	625.00
IUUC-Mmr-061367	Microcebus murinus	90.60	0.00e+00	684.00
IUUC-Mdo-062432	Monodelphis domestica	52.86	7.00e-119	420.00
IUUC-Mmu-064347	Mus musculus	89.04	0.00e+00	755.00
IUUC-Mpu-066864	Mustela putorius furo	91.95	0.00e+00	735.00
IUUC-Nle-070027	Nomascus leucogenys	91.00	0.00e+00	685.00
IUUC-Ocu-074297	Oryctolagus cuniculus	89.93	0.00e+00	696.00
IUUC-Ola-087188	Oryzias latipes	68.22	2.00e-143	502.00
IUUC-Oga-088856	Otolemur garnettii	91.05	0.00e+00	705.00
IUUC-Oar-090278	Ovis aries	84.70	2.00e-180	625.00
IUUC-Pan-092056	Papio anubis	90.60	0.00e+00	724.00
IUUC-Pab-098202	Pongo abelii	90.38	0.00e+00	724.00
IUUC-Pca-100881	Procavia capensis	89.71	0.00e+00	717.00
IUUC-Pva-102181	Pteropus vampyrus	91.05	0.00e+00	730.00
IUUC-Rno-105295	Rattus norvegicus	85.68	0.00e+00	700.00
IUUC-Sha-107163	Sarcophilus harrisii	71.17	3.00e-170	591.00
IUUC-Ssc-115685	Sus scrofa	90.38	0.00e+00	724.00
IUUC-Tgu-116524	Taeniopygia guttata	72.61	7.00e-169	586.00
IUUC-Ttr-129069	Tursiops truncatus	91.47	0.00e+00	693.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence