iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062432

Ensembl Protein ID

ENSMODP00000017409.2

UniProt Accession

F6SV82; F6SV82_MONDO

Protein Name

Uncharacterized protein

Gene Name

PACSIN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000013925.2	ENSMODT00000017734.2	ENSMODP00000017409.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.20e-15	56.0	377	432

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +v++lydy++q++deL++k+Gd ++ +  ee ++gW++g + ++g+ Gl P+n+ve +
   Q: 377  RVRALYDYDGQEQDELSFKAGDELTKL-GEEDEQGWCRG-RLDSGQLGLYPANYVESI 432
           699************************.***********.59*************975 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MSGSYDEATP SMEEITDSFW EVGNYKRTVK RIDDGHRLCN DLMSCLERAK IEKAYAQQLT 60
DWAKRWRQLL EKGQLEDCGP SSYRKLLPEE ERGNSRKEST PRDLLSTFHS DFRYILVFQS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTGGCT CCTATGATGA AGCTACACCT TCGATGGAGG AGATCACCGA CAGCTTCTGG 60
GAGGTGAGAT TCCCCTCTCG CCTTTCTTCT CACTTACCCC TCCCTCCCAA ATTCTAGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR001060--FCH_dom
IPR028518--PACSIN1
IPR001452--SH3_domain

PROSITE

PS50002--SH3

Pfam

PF00611--FCH
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0030137--C:COPI-coated vesicle
GO:0005768--C:endosome
GO:0043209--C:myelin sheath
GO:0032587--C:ruffle membrane
GO:0045202--C:synapse
GO:0005543--F:phospholipid binding
GO:0007015--P:actin filament organization
GO:0045806--P:negative regulation of endocytosis
GO:0048812--P:neuron projection morphogenesis
GO:0097320--P:plasma membrane tubulation
GO:0072657--P:protein localization to membrane
GO:0030100--P:regulation of endocytosis
GO:0048488--P:synaptic vesicle endocytosis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001861	Ailuropoda melanoleuca	52.45	4.00e-126	444.00
IUUC-Bta-013509	Bos taurus	57.85	3.00e-125	441.00
IUUC-Cja-019659	Callithrix jacchus	58.07	6.00e-135	473.00
IUUC-Cfa-020396	Canis familiaris	58.07	1.00e-133	469.00
IUUC-Cpo-022376	Cavia porcellus	57.62	1.00e-131	463.00
IUUC-Csa-023701	Chlorocebus sabaeus	57.85	2.00e-132	466.00
IUUC-Eca-033679	Equus caballus	52.76	9.00e-113	400.00
IUUC-Fca-036314	Felis catus	58.30	2.00e-134	472.00
IUUC-Fal-037300	Ficedula albicollis	54.85	3.00e-125	441.00
IUUC-Ggo-045557	Gorilla gorilla	57.62	5.00e-132	464.00
IUUC-Hsa-045778	Homo sapiens	57.62	5.00e-132	464.00
IUUC-Itr-048856	Ictidomys tridecemlineatus	57.40	1.00e-131	462.00
IUUC-Laf-054465	Loxodonta africana	57.27	8.00e-131	460.00
IUUC-Mcc-055324	Macaca mulatta	57.85	2.00e-132	465.00
IUUC-Meu-056348	Macropus eugenii	62.33	6.00e-143	500.00
IUUC-Mmr-061367	Microcebus murinus	58.97	1.00e-122	433.00
IUUC-Mmu-064347	Mus musculus	58.39	5.00e-135	474.00
IUUC-Mpu-066864	Mustela putorius furo	58.07	5.00e-134	470.00
IUUC-Nle-070027	Nomascus leucogenys	57.04	8.00e-124	436.00
IUUC-Opr-070521	Ochotona princeps	86.74	2.00e-91	329.00
IUUC-Ocu-074297	Oryctolagus cuniculus	58.52	7.00e-126	443.00
IUUC-Oga-088856	Otolemur garnettii	58.52	2.00e-127	448.00
IUUC-Oar-090278	Ovis aries	50.45	2.00e-94	339.00
IUUC-Ptr-091130	Pan troglodytes	87.03	7.00e-94	337.00
IUUC-Pan-092056	Papio anubis	57.85	2.00e-132	466.00
IUUC-Pab-098202	Pongo abelii	57.85	1.00e-132	466.00
IUUC-Pca-100881	Procavia capensis	56.95	3.00e-129	455.00
IUUC-Pva-102181	Pteropus vampyrus	57.85	7.00e-132	463.00
IUUC-Rno-105295	Rattus norvegicus	57.87	3.00e-125	441.00
IUUC-Sha-107163	Sarcophilus harrisii	60.18	3.00e-134	471.00
IUUC-Ssc-115685	Sus scrofa	57.62	1.00e-131	463.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence